Bibliography
- KINO T, HATANAKA H, HASHIMOTO M et al.: FK506, a novel immunosuppressant isolated from a Strepto-myces. I. Fermentation, isolation and physico-chemical and biological characteristics. J. AntibioL Tokyo (1987) 40:1249–1255.
- KINO T, HATANAKA H, MIYATA S et al.: FK506, a novel immunosuppressant isolated from a Streptomyces. II. Irnm un o sup p r es sive effect of FK506 in vitro. .1 Antibiot. Tokyo (1987) 40:1256–1265.
- STARZL TE, TODO S, FUNG J, DEMETRIS AJ, VENKATA-RAMMAN R, JAIN A: FK506 for liver, kidney and pancreas transplantation. Lancet (1989) 2:1000–1004.
- KARPAS A, LOWDELL M, JACOBSON SK, HILL F: Inhibi-tion of human immunodeficiency virus and growth of infected T cells by the immunosuppressive drugs cyclosporin A and FK506. Proc. Natl. Acad. ScL USA (1992) 89:8351–8355.
- LYONS WE, GEORGE EB, DAWSON TM, STEINER JP, SNYDER SH: Irnmunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia. Proc. Natl. Acad. Sci. USA (1994) 91:3191–3195.
- SNYDER SH, SABATINI DM: Immunophilins and the nervous system. Nature Med. (1995) 1:32–37.
- GOLD BG, KATOH K, STORM-DICKERSON T: The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve. J Neurosci. (1995) 15:7509–7516.
- STEINER JP, HAMILTON GS, ROSS DT et al.: Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models. Proc. Natl. Acad. Sci. USA (1997) 94:2019–2024.
- FISCHER G, WITTMANN-LIEBOLD B, LANG K, KIEFHABER T, SCHMID FX: Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins. Nature (1989) 337:476–478.
- SIEKIERKA JJ, HUNG SHY, POE M, LIN CS, SIGAL NH: A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin. Nature (1989) 341:755–757.
- HARDING MW, GALAT A, UEHLING DE, SCHREIBER SL: A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase. Nature (1989) 341:758–760.
- KOFRON JL, KUZMIC P, KISHORE V, COLON-BONILLA E,RICH DH: Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay. Biochemistry (1991) 30:6127–6134.
- SMALL SL, FUKUI MB, BRAMBLETT GT, EIDELMAN BH: Immunosuppression-induced leukoencephalopathy from tacrolimus (FK506). Ann. Neurol. (1996) 40:575–580.
- TOROCSIK HV, CURLESS RG, POST J, TZAKIS AG, PEARSE L: FK506-induced leukoencephalopathy in children with organ transplants. Neurology (1999) 52:1497–1500.
- SINGH N, BONHAM A, FUKUI M: Irnmunosuppressive-associated leukoencephalopthy in organ transplant recipients. Transplantation (2000) 69:467–472.
- LARNER AJ: Neuronal apoptosis as a therapeutic target in neurodegenerative disease. Exp. Opin. Ther. Patents (2000) 10: (In Press)
- CHEN MS, HUBER AB, VAN DEN HAAR ME et al.: Nogo-Ais a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1. Nature (2000) 403:434–439.
- GRANDPRE. T, NAKAMURA F, VARTANIAN T, STRITT-MATTER SM: Identification of the Nogo inhibitor of axon regeneration as a reticulon protein. Nature (2000) 403:439–444.
- PRINJHA R, MOORE SN, VINSON M et al.: Inhibitor ofneurite outgrowth in humans. Nature (2000) 403:383–384.
- MCKERRACHER L, DAVID S, JACKSON DL, KOTTIS V, DUNN RJ, BRAUN PE: Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth. Neuron (1994) 13:805–811.
- Rho family antagonists and their use to block inhibi-tion of neurite growth. Exp. Opin. Ther. Patents (1999) 9(10:1571–1574.