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Review

CC-1065 and the duocarmycins: recent developments

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Pages 1853-1871 | Published online: 25 Feb 2005

Bibliography

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  • ••A very complete and extensive review on CC-1065 andduocarmycins.
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  • ••This report summarises the studies performed with the aimto demonstrate the relationship between cytotoxicity and solvolytic stability of cyclopropane ring.
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  • ••This review summarises all the synthetic approach for thesynthesis of CC-1065 and its derivatives.
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  • ••This report summarises all the studies performed in order tounderstand the mechanism of action of CC-1065, and duocarmycins and new considerations on the basis of recent experimental observations are reported.
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  • •This article reports a new approach for ADEPT using CC-1065 derivatives.
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