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Review

New directions in the treatment of anxiety disorders

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Pages 389-402 | Published online: 25 Feb 2005

Bibliography

  • KESSLER RC, MCGONAGLE KA, ZHAO S et al.: Lifetime and, 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch. Gen. Psychiatry (1994) 51:8–19.
  • •Epidemiological study considered the best estimation of the prevalence of anxiety disorders in the general population.
  • MARKOWITZ JS, WEISSMAN MM, OUELLETTE R, LISH JD, KLERMAN GL: Quality of life in panic disorder. Arch. Gen. Psychiatry (1989) 46:984–992.
  • WEISSMAN MM: Panic disorder: impact on quality of life. J. Clin. Psychiatry (1991) 52 (Supp1.9):6–8.
  • CANDILIS PJ, MCLEAN RY, OTTO MW et al.: Quality of life in patients with panic disorder. J. Nerv. Ment. Dis. (1999) 187:429–434.
  • TARLOV AR, WARE JE, JR., GREENFIELD S, NELSON EC, PERRIN E, ZUBKOFF M: The Medical Outcomes Study. An application of methods for monitoring the results of medical care. JAMA (1989) 262:925–930.
  • CANDILIS PJ, POLLACK MH: The hidden costs of untreated anxiety disorders. Han'. Rev. Psychiatry (1997) 5:40–42.
  • WOODS JH, KATZ JL, WINGER G: Benzodiazepines: use,abuse and consequences. Pharmacol. Rev. (1992) 44:151–347.
  • KENT JM, COPLAN JD, GORMAN JM: Clinical utility of the selective serotonin reuptake inhibitors in the spectrum of anxiety. Biol. Psychiatry (1998) 44:812–824.
  • Diagnostic and Statistical Manual of Mental Disorders. 4th ed. American Psychiatric Association, Washington, USA (1994).
  • Practice guideline for the treatment of patients with panic disorder. Work Group on Panic Disorder. American Psychiatric Association. Am. J. Psychiatry (1998) 155 (Suppl. 5):1–34.
  • WITTCHEN HU, ZHAO S, KESSLER RC, EATON WW: DSM-III-R generalized anxiety disorder in the National Comorbidity Survey. Arch. Gen. Psychiatry (1994) 51:355–364.
  • DAVIDSON JR, DUPONT RL, HEDGES D, HASKINS JT: Efficacy, safety and tolerability of venlafaxine extended release and buspirone in outpatients with generalized anxiety disorder. J. Clin. Psychiatry (1999) 60:528–535.
  • BRESLAU N, DAVIS GC, ANDRESKI P, PETERSON E: Traumatic events and posttraumatic stress disorder in an urban population of young adults. Arch. Gen. Psychiatry (1991) 48:216–222.
  • RESNICK HS, KILPATRICK DG, DANSKY BS, SAUNDERS BE, BEST CL: Prevalence of civilian trauma and posttraumatic stress disorder in a representative national sample of women. J Consult. Clin. Psycho]. (1993) 61:984–991.
  • DAVIDSON JRT, MARCH JS: Traumatic stress disorders. In: Psychiatry 1st ed Tasman A, Kay J, Lieberman JA (Eds.), W.B. Saunders Company, Philadelphia, USA (1997):1085–1099.
  • SOLOMON SD, DAVIDSON JR: Trauma: prevalence, impairment, service use and cost. J. Clin. Psychiatry (1997) 58 (Supp1.9):5–11.
  • FRIEDMAN MJ: Current and future drug treatment for posttraumatic stress disorder patients. Psychiatric Ann. (1998) 28:461–468.
  • DAVIDSON JR, MALIK ML, SUTHERLAND SN: Response characteristics, to antidepressants and placebo in post-traumatic stress disorder. Int. Clin. Psychopharmacol. (1997) 12:291–296.
  • HERTZBERG MA, FELDMAN ME, BECKHAM JC, DAVIDSON JR: Trial of trazodone for posttraumatic stress disorder using a multiple baseline group design. J. Clin. Psychopharmacol. (1996) 16:294–298.
  • WELLS GB, CHU C, JOHNSON R et al.: Buspirone in thetreatment of post-traumatic stress disorder. J. Clin. Psychiatry (1991) 55:517–522.
  • YEHUDA R, GILLER EL, SOUTHWICK SM, LOWY MT, MASON JW: Hypothalamic-pituitary-adrenal dysfunc-tion in posttraumatic stress disorder. Biol. Psychiatry (1991) 30:1031–1048.
  • POST RM, WEISS SRB, SMITH MA: Sensitization andkindling: implications for the evolving neural substrate of PTSD. In: Neurobiological and Clinical Consequences of Stress: From Normal Adaptation to PTSD. Friedman MJ, Charney DS, Deutch AY (Eds.), Lippincott-Raven Press, Philadelphia, USA (1995):203–224.
  • FRIEDMAN MJ, SOUTHWICK SM: Towards pharmaco-therapy for PTSD. In: Neurobiological and Clinical Consequences of Stress: From Normal Adaptation to PTSD. Friedman MJ, Charney DS, Deutch AY (Eds.), Lippincott-Raven Press, Philadelphia, USA (1995):465–481.
  • GOODMAN WK, PRICE LH, RASMUSSEN SA et al.: TheYale-Brown Obsessive Compulsive Scale. I. Develop-ment, use and reliability. Arch. Gen. Psychiatry (1989) 46:1006–1011.
  • KARNO M, GOLDING JM, SORENSON SB, BURNAM MA:The epidemiology of obsessive-compulsive disorder in five US communities. Arch. Gen. Psychiatry (1988) 45:1094–1099.
  • HOLLANDER E, STEIN D, BROATCH J: A pharma-coeconomic and quality of life study of OCD. Scientific Abstracts of the 34th Annual Meeting of the American College of Neuropsychopharmacology. San Juan, Puerto Rico, December 11-15 (1995):155.
  • ELLINGROD VL: Pharmacotherapy of primary obsessive-compulsive disorder: review of the litera-ture. Pharmacotherapy (1998) 18:936–960.
  • VAN AMERINGEN M, MANCINI C, STYAN G, DONISON D: Relationship of social phobia with other psychiatric illness. J. Affect. Disord. (1991) 21:93–99.
  • LADER M: The clinical relevance of treating social phobia. J. Affect. Disord. (1998) 50\(Suppl. 1):S29–34.
  • Lydiard RB: The role of drug therapy in social phobia. J. Affect. Disord. (1998) 50\(Suppl. 1):S35–39.
  • ANTONY MH, BARLOW DH: Social and specific phobias. In: Psychiatry. 1st ed Tasman A, Kay J, Lieberman JA (Eds.), W.B. Saunders Company, Philadelphia, USA (1997)1037–1059.
  • HENNINGER GR: Special challenges in the investigationof the neurobiology of mental illness. In: Neurobiology of, Mental Illness. Charney DS, Nestler EJ, Bunney BS (Eds.), Oxford University Press, New York, USA (1999):89–99.
  • GOA KL, WARD A: Buspirone. A preliminary review of its pharmacological properties and therapeutic efficacy as an amdolytic. Drugs (1986) 32:114–129.
  • TAYLOR DP, MOON SL: Buspirone and related compounds as alternative amdolytics. Neuropeptides (1991) 19(Suppl.):15–19.
  • LECRUBIER Y, PUECH AJ, AZCONA A, BAILEY PE, LATASTE X: A randomized double-blind placebo-controlled study of tropisetron in the treatment of outpatients with generalized anxiety disorder. Psycho-pharmacology (1993) 112:129–133.
  • KRAMER MS, CUTLER NR, BALLENGER JC et al.: A placebo-controlled trial of L-365,260, a CCKB antago-nist, in panic disorder. Biol. Psychiatry (1995) 37:462–466.
  • HOGG S: A review of the validity and variability of the elevated plus-maze as an animal model of anxiety. Pharmacol. Biochem. Behav. (1996) 54:21–30.
  • GRIEBEL G: 5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: more than 30 years of research. Pharmacol Ther. (1995) 65:319–395.
  • ••Exhaustive review of serotonergic agents used in animalanxiety models that also addresses difficulties in evaluating the validity of such models.
  • FILE SE: Behavioural detection of anxiolytic action. In: Experimental Approaches to Anxiety and Depression. Elliot JM, Heal DJ, Marsden CA (Eds.), J Wiley, Chichester, UK (1992):25–44.
  • RODGERS RJ, DALVI A: Anxiety, defence and the elevated plus-maze. NeuroscL Biobehav. Rev. (1997) 21:801–810.
  • GRAEFF FG: Serotonergic systems. Psychiatr. Clin. North Am. (1997) 20:723–739.
  • OLIVIER B, SOUDIJN W, VAN WIJNGAARDEN I: The 5-HT1A receptor and its ligands: structure and function. Prog. Drug Res. (1999) 52:103–165.
  • DEN BOER JA, WESTENBERG HG: Behavioral, neuroen-docrine and biochemical effects of 5- hydroxytrypto-phan administration in panic disorder. Psychiatry Res. (1990) 31:267–278.
  • CHARNEY DS, BREMNER JD: The neurobiology of anxiety disorders. In: Neurobiology of Mental Illness. Charney DS, Nestler EJ, Bunney BS (Eds.), Oxford University Press, New York, USA (1999):494–517.
  • •Recent review of neurobiological findings in anxiety disorders.
  • SOUTHWICK SM, KRYSTAL JH, BREMNER JD et al.: Noradrenergic and serotonergic function in posttrau-matic stress disorder. Arch. Gen. Psychiatry (1997) 54:749–758.
  • ARORA RC, FICHTNER CG, O'CONNOR F, CRAYTON JW:Paroxetine binding in the blood platelets of post-traumatic stress disorder patients. Life ScL (1993) 53:919–928.
  • NAYEEM N, GREEN TP, MARTIN IL, BARNARD EA: Quater-nary structure of the native GABAA receptor determined by electron microscopic image analysis. J. Neurochem. (1994) 62:815–818.
  • MEHTA AK, TICKU MK: An update on GABAA receptors. Brain Res. Rev. (1999) 29:196–217.
  • ••Recent, extensive review of the structure, function andpharmacology of GABAA receptors.
  • WHITING PJ, MCKERNAN RM, WAFFORD KA: Structureand pharmacology of vertebrate GABAA receptor subtypes. Int. Rev. Neurobiol. (1995) 38:95–138.
  • WISDEN W, LAURIE DJ, MONYER H, SEEBURG PH: Thedistribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. j Neurosci. (1992) 12:1040–1062.
  • LAURIE DJ, SEEBURG PH, WISDEN W: The distribution of13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum. J. Neurosci. (1992) 12:1063–1076.
  • WOODS SW, CHARNEY DS, SILVER JM, KRYSTAL JH, HENINGER GR: Behavioral, biochemical and cardiovas-cular responses to the benzodiazepine receptor antagonist flumazenil in panic disorder. Psychiatry Res. (1991) 36:115–127.
  • NUTT DJ, GLUE P, LAWSON C, WILSON S: Flumazenil provocation of panic attacks. Evidence for altered benzodiazepine receptor sensitivity in panic disorder. Arch. Gen. Psychiatry (1990) 47:917–925.
  • ROY-BYRNE PP, LEWIS N, VILLACRES E et al.: Preliminaryevidence of benzodiazepine subsensitivity in panic disorder. Biol. Psychiatry (1989) 26:744–748.
  • ROY-BYRNE P, WINGERSON DK, RADANT A, GREENBLATT DJ, COWLEY DS: Reduced benzodiazepine sensitivity in patients with panic disorder: comparison with patients with obsessive-compulsive disorder and normal subjects. Am. J. Psychiatry (1996) 153:1444–1449.
  • SCHLEGEL S, STEINERT H, BOCKISCH A, HAHN K, SCHLOESSER R, BENKERT 0: Decreased benzodiazepine receptor binding in panic disorder measured by IOMAZENIL-SPECT. A preliminary report. Eur. Arch. Psychiatry Clin. Neurosci. (1994) 244:49–51.
  • KUIKKA JT, PITKANEN A, LEPOLA U et al: Abnormalregional benzodiazepine receptor uptake in the prefrontal cortex in patients with panic disorder. Nucl. Med. Commun. (1995) 16:273–280.
  • LYDIARD RB, BALLENGER JC, RICKELS K: A double-blindevaluation of the safety and efficacy of abecarnil, alprazolam and placebo in outpatients with general-ized anxiety disorder. Abecarnil Work Group. J. Clin. Psychiatry (1997) 58 (Suppl. 11) :11–18.
  • POLLACK MH, WORTHINGTON JJ, MANFRO GG, OTTOMW, ZUCKER BG: Abecarnil for the treatment of generalized anxiety disorder: a placebo-controlled comparison of two dosage ranges of abecarnil and buspirone. j Clin. Psychiatry (1997) 58\(Suppl. 10:19–23.
  • AUFDEMBRINKE B: Abecarnil, a new beta-carboline, in the treatment of anxiety disorders. Br. J. Psychiatry Suppl. (1998) 34:55–63.
  • BETANCUR C, AZZI M, ROSTENE W: Nonpeptide antago-nists of neuropeptide receptors: tools for research and therapy. Trends Pharmacol. ScL (1997) 18:372–386.
  • •A discussion of the issues involved in creating and using non-peptide antagonists of neuropeptide receptors.
  • HOLSBOER F: The rationale for corticotropin-releasing hormone, receptor (CRH-I) antagonists to treat depression and anxiety. J. Psychiatr. Res. (1999) 33:181–214.
  • ••Extensive review of the role of CRH in psychiatric disorders.
  • ARBORELIUS L, OWENS MJ, PLOTSKY PM, NEMEROFF CB: The, role of corticotropin-releasing factor in depres-sion and anxiety disorders. J. Endocrinof (1999) 160:1–12.
  • GRIEBEL G: Is there a future for neuropeptide receptor ligands, in the treatment of anxiety disorders? Pharmacol. Ther. (1999) 82:1–61.
  • ••Exhaustive review of neuropeptides and related agentsconsidered relevant to anxiety disorders.
  • VAN BOCKSTAELE EJ, COLAGO EE, VALENTINO RJ: Corticotropin-releasing factor-containing axon terminals synapse onto catecholamine dendrites and may presynaptically modulate other afferents in the rostral pole of the nucleus locus coeruleus in the rat brain. J. Comp. Neurol. (1996) 364:523–534.
  • VALENTINO RJ, WEHBY RG: Corticotropin-releasing factor: evidence for a neurotransmitter role in the locus ceruleus during hemodynamic stress. Neuroen-docrinology (1988) 48:674–677.
  • BUTLER PD, WEISS JM, STOUT JC, NEMEROFF CB: Corticotropin-releasing factor produces fear-enhancing and behavioral activating effects following infusion into the locus coeruleus. J. Neurosci. (1990) 10:176–183.
  • PANDE AC: Lack of efficacy of a cholecystokinin-B antagonist in anxiety disorders. Biol. Psychiatry (1997) 42:11–19.
  • ADAMS JB, PYKE RE, COSTA J et al: A double-blind,placebo-controlled study of a CCKB receptor antago-nist, CI-988, in patients with generalized anxiety disorder. J. Gun. Psychopharmacol. (1995) 15:428–434.
  • DUMONT Y, FOURNIER A, ST-PIERRE S, QUIRION R: Characterization of neuropeptide Y binding sites in rat brain membrane preparations using [1251] [Leu31,Pro34]peptide YY and [1251]peptide YY3-36 as selective Y1 and Y2 radioligands. J. Pharmacol. Exp. Ther. (1995) 272:673–680.
  • BOULENGER JP, JERABEK I, JOLICOEUR FB, LAVALLEE YJ,LEDUC R, CADIEUX A: Elevated plasma levels of neuropeptide Y in patients with panic disorder. Am. J. Psychiatry (1996) 153:114–116.
  • OTSUKA M, YOSHIOKA K: Neurotransmitter functionsof mammalian tachykinins. Physiol. Rev. (1993) 73:229–308.
  • MAGGI CA: The mammalian tachykinin receptors. Gen. Pharmacol,. (1995) 26:911–944.

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