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Recent developments on DHEA supplementation in the substitutive therapy of primary adrenal insufficiency

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Pages 1911-1918 | Published online: 25 Feb 2005

Bibliography

  • ADDISON T: The constitutional and local effects of diseases of the suprarenal capsules. In a collection of the published writing of the late Thomas Addison, MD, physician to: Guy's Hospital. London: New Sydenham Society 1868. Reprinted in Medical Classics (1937) 2:244–293.
  • LAURETI S, VECCHI L, SANTEUSANIO F, FALORNI A: Is the prevalence of Addison's disease underestimated? j Chit. Eridocnhol Metab. (1999) 84:1762.
  • LAURETI S, ARVAT E, CANDELORO P et al: Low dose (11.4 ACTH test in the evaluation of adrenal dysfunction in pre-clinical Addison's disease. Clin. Eridocnhol (2000) 53:107–115
  • •A study demonstrating that the ACTH low dose test has a high diagnostic sensitivity and specificity for mild forms of PAT.
  • DICKSTEIN G: Hypothalamo-pituitary-adrenal axis testing: nothing is sacred and caution in interpretation is needed. CM]. Endocrine]. (2001) 54:15–16.
  • OELKERS W: Adrenal insufficiency. N Engl. J. Med. (1996) 335:1206–1212.
  • LAURETI S, AUBOURG E CALCINARO F et al.: Etiological diagnosis of primary adrenal insufficiency using an original flowchart of immune and biochemical markers. J CM]. Endocrine]. Metab. (1998) 83:3163–1368.
  • WINQVIST 0, KARLSSON FA, KAMPE 0: 21-hydroxylase, a major autoantigen in idiopathic Addison's disease. Lancet (1992) 339:1559–1562.
  • BEDNAREK J, FURMANIAK J, WEDLOK N etal.: Steroid 21-hydroxylase is a major autoantigen involved in adult onset autoimmune Addison's disease. FEBS Lett. (1992) 309:51–55.
  • FALORNI A, NIKOSHKOV A, LAURETI S et al.: High diagnostic accuracy for idiopathic Addison's disease with a sensitive radiobinding assay for autoantibodies against recombinant human 21-hydroxylase. I CM]. Endocrine]. Metab. (1995) 80:2752–2755.
  • COLLS J, BETTERLE C, VOLPATO M et al.: Immunoprecipitation assay for autoantibodies to steroid 21-hydroxylase in autoimmune adrenal diseases. CM]. Chem. (1995) 41:375–380.
  • TANAKA H, PEREZ MS, POWELL Met al.: Steroid 21-hydroxylase autoantibodies: measurements with a new immunoprecipitation assay. I CM]. Endocrine]. Metab. (1997) 82:1440–1446.
  • FALORNI A, LAURETI S, NIKOSHKOV A et al.: 21-hydroxylase autoantibodies in adult patients with endocrine autoimmune diseases are highly specific for Addison's disease. Clin. Exp. Immune] (1997) 107:341–346.
  • LAURETI S, FALORNI A, VOLPATO M et al.: Absence of circulating adrenal autoantibodies in adult-onset X-linked adrenoleukodystrophy. Herm. Metab. Res. (1996) 28:319–322.
  • LAURETI S, CASUCCI G, SANTEUSANIO F et al.: X-linked adrenoleukodystrophy is a frequent cause of 'idiopathic' Addison's disease in young-adult male patients. j Clin. Endocnno] Metab. (1996) 81:470–474.
  • ZANARIA E, MUSCATELLI F, BARDONI B et a]: An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita. Nature (1994) 372(6507):635–641.
  • CLARK AJL, MC LOUGHLIN L, GROSSMAN A: Familial glucocorticoid deficiency associated with point mutation in the adrenocorticotropin receptor. Lancet (1993) 341:461.
  • MOSER HW: Adrenoleukodystrophy: phenotype, genetics, pathogenesis and therapy. Brain (1997) 120:1485.
  • AUBOURG P. The expanding world of primary adrenal insufficiency. Eur. Endocrine]. (1997) 137:10.
  • MUSCATELLI E STROM TM, WALKER AP et al. Mutations in the DAX-1 gene rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism. Nature (1994) 372(6507):672–676.
  • WEBER A, CLARK AJL: Mutations of the ACTH receptor gene are only one cause of familial glucocorticoid deficiency. Hum. Me] Gen. (1994) 3:585.
  • TSIGOS C, ARAI K, LATRONICO AC, DIGEORGE A, RAPAPORT R, CHROUSOS GP: A novel mutation of the adrenocorticotropin receptor (ACTH-R) gene in a family with syndrome of isolated glucocorticoid deficiency, but no ACTH-R abnormalities in two families with the triple A syndrome. j Clin. Endocnno] Metab. (1995) 80:2186.
  • ALLGROVE J, CLAYDEN GS, GRANT BD, MCCAULAY JC: Familial glucocorticoid deficiency with achalasia of the cardia and deficient tear production. Lancet (1978) I:1284.
  • WEBER A, WIENKER TF, JUNG M et al.: Linkage of the gene for the triple A syndrome to chromosome 12q13 near the Type II keratin gene cluster. Hum. Me] Genet. (1996) 5:2061.
  • HANDSCHUG K, SPERLING S, KIM YOON SJ et al.: Triple A syndrome is caused by mutations in AAAS a new WD-repeat protein gene. Hum. Me] Gen. (2001) 10:283: 290.
  • TULLIO-PETEL A, SALOMON R, HADJ-RABIA S et al.: Mutant WD-repeat protein in triple-A syndrome. Nat. Genet. (2000) 26:332–335.
  • ESTEBAN NV, LOUGHLIN T, YERGEY AL et al.: Daily cortisol production rate in man determined by stable isotope dilution/ mass spectrometry. I Clin. Endocrine] Metab. (1991) 72:39–45.
  • PEACEY SR, GUO CY, ROBINSON AM et al.: Glucocorticoid replacement therapy: are patients over treated and does it matter? Clin. Endocrine] (1997) 46:255–261.
  • •A study suggesting that a high proportion of patients on conventional corticosteroid replacement therapy are overtreated or on inappropriate replacement regimen.
  • BESSER JM, JEFFCOATE WJ: Adrenal disease. Br Med .j (1976) 1:448–451.
  • ZELISSEN PMJ, CROUGHS, VAN RIJK PP, RAYMAKERS JA: Effect of glucocorticoid replacement therapy on bone mineral density in patients with Addison's disease. Ann. Intern. Med. (1994) 120:207–210.
  • GROVES RV, TOMS GC, HOUGHTON BJ, MONSON JP: Corticosteroid replacement therapy: twice or thrice daily? J Royal Soc. Med. (1988) 81:514–516.
  • HOWLETT T: An assessment of optimal hydrocortisone replacement therapy. Clin. Endocnno] (1997) 46:263–268.
  • •The data obtained in this study indicate that an optimal replacement is achieved with a thrice daily hydrocortisone regimen.
  • MONSON JP: The assessment of glucocorticoid replacement therapy. Clin Endocnno] (1997) 46:269–270.
  • SCOTT RS, DONALD RA, ESPINER EA: Plasma ACTH and cortisol profiles in Addisonian patients receiving conventional substitution therapy. Clin Endocnno] (Oxf) (1978) 9:571–576.
  • TRAINER PJ: Urinary free cortisol in the assessment of hydrocortisone replacement therapy. Herm. Metab. Res. (1993) 25:117–120.
  • OELKERS W, BUCHEN S, DIEDERICH S, KRAIN J, MUHME S, SCHONESHOFER M: Impaired renal 11P-oxidation of 9a-fluocortisol, an explanation for its mineralcorticoid potency.?Clin. Endocrine] Metab. (1994) 78:928–932.
  • OELKERS W: Diagnosis and therapy surveillance in Addison's disease: rapid adrenocorticotropin (ACTH) test and measurement of plasma ACTH, renin activity and aldosterone. I Clin. Endocrine] Metab. (1992) 75:259
  • FIAD TM, CONWAY JD, CUNNINGHAM SK, MCKENNA TJ: The role of plasma renin activity in evaluating the adequacy of mineralcorticoid replacement in primary adrenal insufficiency. (1996) Clin. Endocrine] 45:529–534.
  • OELKERS W: Dehydroepiandrosterone for adrenal insufficiency. N Eng] j Med. (1999) 341:1073–1074.
  • ACHERMANN JC, SILVERMAN BL: Dehydroepiandrosterone replacement for patients with adrenal insufficiency. Lancet (2001) 357:1381–1382.
  • KROBOTH PD, SALEK FS, PITTENGER AL, FABIAN TJ, FRYE RE: DHEA and DHEA-S: a review Pharmacy] (1999) 39:327–348.
  • ARLT W, CALLIES F, VAN VIJMEN JC et al.: Dehydroepiandrosterone replacement in women with adrenal insufficiency. N Eng]?Med. (1999) 241:1013–1020.
  • ••The first study showing a beneficial effectof DHEA replacement therapy in women with adrenal insufficiency.
  • ARLT W, CALLIES F, VAN VLUMEN JC etal.: Oral dehydroepiandrosterone for adrenal androgen replacement: pharmacokinetics and peripheral conversion to androgens and estrogens in young healthy females after dexamethasone suppression. j Cliii. Endocnno] Metab. (1998) 83:1928–1934.
  • GEBRE-MEDHIN G, HUSEBYE ES, MALLMIN H et a]: Oral dehydroepiandrosterone (DHEA) replacement therapy in women with Addison's disease. (2000) Clin. Endocrine]. 52: 775–780.
  • •A study indicating that the daily replacement dose of 50 mg of DHEA results in near physiological levels of DHEA and other adrenal androgens in women with Addison's disease, without severe side effects.
  • HUNT PJ, GURNELL EM, HUPPERT FA et al: Improvement in mood and fatigue after dehydroepiandrosterone replacement in Addison's disease in a randomized, double blind trial. ..J. Clin. Endocrine]. Metab. (2000) 85 :4650–4656.
  • ••A study indicating that DHEA replacement corrects the androgen steroid defect in males with PAT.
  • CALLIES F, FASSNACHT M, VAN VLIJMEN JC et al.: Dehydroepiandrosterone replacement in women with adrenal insufficiency: effects on body composition, serum leptin, bone turnover, and exercise capacity. j art. Endocnitol. Metab. (2001) 86:1968–1972.
  • •A study showing that DHEA replacement does not have a significant effect on carbohydrate metabolism, body composition, or exercise capacity in patients with adrenal insufficiency.

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