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Miscellaneous

The use of prostaglandin D2 receptor antagonists to treat allergic rhinitis

Pages 1657-1661 | Published online: 02 Mar 2005

Bibliography

  • HOWARTH PH: Mediators of nasal blockage in allergic rhinitis. Allergy (1997) 52(40Suppl.):12–18.
  • ••Sets the biological context for thisapproach.
  • COLEMAN RA, SMITH WL, NARUMIYA S: International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Phannacol Rev. (1994) 46:205–229.
  • HIRAI H, TANAKA K, YOSHIE O et al: Prostaglandin D2 selectively induces chemotaxis in T helper Type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2. J. Exp. Med. (2001) 193(2):255–261.
  • •The identification of CRTH2 as a DP receptor subtype.
  • BOIE Y, SAWYER N, SLIPETZ DM et al.: Molecular cloning and characterization of the human prostanoid DP receptor. J. Biol. Chem. (1995) 270(32):18910–18916.
  • •Clearly defines the ligand specificity of the DP receptor.
  • JOHNSTON SL, SMITH S, HARRISON J, RITTER W, HOWARTH PH: The effect of BAY u3405, a thromboxane receptor antagonist, on prostaglandin D2-induced nasal blockage. I Allergy Chia. Immunol (1993) 91(4):903–909.
  • •Demonstrating the ineffectiveness of ramatroban at low doses.
  • MOTOBAYASHI Y, IMAGAWA W, SAIDA K: [Ramatroban (Baynas): a review of its pharmacological and clinical profile]. Nippon Yakurigaku Zasshi (2001) 118(6)397–402.
  • •Summarises the efficacy observed in studies with higher doses of ramatroban.
  • SUGIMOTO H, SHICHIJO M, IINO T et al.: An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration M vitro. Pharmacol Exp. The]: (2003) 305(1):347–352.
  • •Clear indication that ramatroban acts on CRTH2 receptors as well as on TP receptors.
  • WRIGHT DH, FORD-HUTCHINSON AW, CHADEE K, METTERS KM: The human prostanoid DP receptor stimulates mucin secretion in LS174T cells. Br. J. Pharmacol (2000) 131(8):1537–1545.
  • ARIMURA A, YASUI K, KISHINO J et al.: Prevention of allergic inflammation by a novel prostaglandin receptor antagonist, S-5751. J. Pharmacol Exp. The]: (2001) 298(2):411–419.
  • O'NEILL GP, BERTHELLETTE C, BOYD M et al.: Characterization of a novel DP receptor antagonist. Am. Respir. Crit. Care Med. (2003) 167:A105.
  • JONES TR, SAVOIE C, ROBICHAUD A et al.: Studies with a DP receptor antagonist in sheep and guinea pig models of allergic rhinitis. Am. I Respir. Crit. Care Med. (2003) 167:A105.
  • HIRATA M, KAKIZUKA A, AIZAWA M et al.: Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene. Proc. Natl. Acad. Sci. USA (1994) 91(23):11192–11196.

Websites

  • www.ono.cojp/jp/ir_info/kaihatuhin/pdf/ 1532h_kai.pdf Japanese version of the product pipeline of Ono Pharmaceuticals.

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