Bibliography
- DUMONT FJ: Immunosuppressive strategies for prevention of transplant rejection. Expert. Opin. Then Patents (2001) 11:377–404.
- DUMONT FJ: Transplantation tolerance-challenges and opportunities for drug development. Carr. Opin. Investig. Drugs (2002) 3:1453–1457.
- WRIGHT GJ, JONES M, PUKLAVEC MJ, BROWN MH, BARCLAY AN: The unusual distribution of the neuronal/lymphoid cell surface CD200 (0X2) glycoprotein is conserved in humans. Immunology (2001) 102:173–179.
- BARCLAY AN, WRIGHT GJ, BROOKE G,BROWN MH: CD200 and membrane protein interactions in the control of myeloid cells. Trends Immunol (2002) 23:285–290.
- ••Review of CD200 and its receptors andtheir potential role in the regulation of myeloid cell functions.
- WRIGHT GJ, PUKLAVEC MJ, WILLIS AC et al.: Lymphoid/neuronal cell surface 0X2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function. Immunity (2000) 13:233–242.
- ••Generation and characterisation of CD200deficient mice. Shows that CD200 may play a role in dampening myeloid cell functions contributing to EAE and CIA.
- GORCZYNSKI RM, CHEN Z, FU XM, ZENG H: Increased expression of the novel molecule OX-2 is involved in prolongation of murine renal allograft survival. Transplantation (1998) 65:1106–1114.
- •First evidence that CD200 is involved in irnmunoregulation.
- HOEK RM, RUULS SR, MURPHY CA et al.: Down-regulation of the macrophage lineage through interaction with 0X2 (CD200). Science (2000) 290: 1768-1771.
- ••Isolation and characterisation of CD200R.
- GORCZYNSKI RM, CATTRAL MS, CHEN Z et al.: An immunoadhesin incorporating the molecule OX-2 is a potent immunosuppressant that prolongs allo- and xenograft survival. Immunol (1999) 163: 1554-1660.
- ••Demonstrates that the CD200:Fc exertsirmnunosuppressive effects in mice.
- GORCZYNSKI RM: Transplant tolerance modifying antibody to CD200 receptor, but not CD200, alters cytokine production profile from stimulated macrophages. Ear. Immunol (2001) 31:2331–2337.
- GORCZYNSKI RM, HU J, CHEN Z, KAI Y, LEI J: A CD200FC immunoadhesin
- •• prolongs rat islet xenograft survival in mice. Transplantation (2002) 73:1948–1953.
- ••Demonstrates that cross-linking CD200Rwith CD200:Fc or anti-CD 200R mAb prolongs xenograft survival in mice.
- GORCZYNSKI RM, CHEN Z, LEE L, YU K, HU J: Anti-CD200R ameliorates collagen-induced arthritis in mice. Clin. Inonunol. (2002) 104:256–264.
- ••Demonstrates that cross-linking CD200R withCD200:Fc or anti-CD200R mAb ameliorates CIA in mice, even after disease onset.
- DIEHL S, RINCON M: The two faces of IL-6 on Thl/Th2 differentiation. Ma Inonunol. (2002) 39:531–536.
- DUMONT FJ: Modulation of Thl and Th2 responses for immunotherapy. Expert Opin. flier. Patents (2002) 12:341–367.
- HAYDAY A, TIGELAAR R: Immunoregulation in the tissues by 78 T cells. Nat. Rev Innnunol. (2003) 3:233–242.
- RAVETCH JV, LANIER LL: Immune inhibitory receptors. Science (2000) 290:84–89.
- NATHAN C: Points of control in inflammation. Nature (2002) 420:846–852.
- MARCH ME, RAVICHANDRAN K: Regulation of the immune response by SHIP. kninunol (2002) 14:37–47.
- LANIER LL, BAKKER BH: The ITAM-bearingtransmembrane adaptor DAP12 in lymphoid and myeloid cell function. Inonunol. Today(2000) 21:611–614.
- WILSON MJ, LINDQUIST JA, TROWSDALE J: DAP12 and KAP10 (DAP10)-novel transmembrane adapter proteins of the CD4 family. kninunol Res. (2000) 22:21–42.
- GERBER JS, MOSSER DM: Stimulatory and inhibitory signals originating from the macrophage Fcy receptors. Microbes Infect. (2001) 3:131–139.
- CHUNG YH, MEANS RE, CHOI JK, LEE BS, JUNG JU: Kaposi's sarcoma-associated herpesvirus 0X2 glycoprotein activates myeloid-lineage cells to induce inflammatory cytokine production. " Vim/. (2002) 76:4688–4698.
- GORDON CJ, GRAFTON G, WOOD PM, LARCHE M, ARMITAGE RJ: Modelling the human immune response: can mice be trusted? Carr: Opin. Phannacol (2001) 1:431–435.
- LUTZ M, SCHULER G: Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Innnunol. (2002) 23(9)445–449.
- THOMPSON AG, THOMAS R: Induction of immune tolerance by dendritic cells: implications for preventative and therapeutic immunotherapy of autoimmune disease. kninunol Cell. Biol. (2002) 80:509–519.
- MARTIN E, O'SULLIVAN B, LOW P, THOMAS R: Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10. kninunio, (2003)18:155–167.
- GREENWALD RJ, LATCHMAN YE, SHARPE AH: Negative coreceptors on lymphocytes. Carr: Opin. Innnunol. (2002) 14:391–396.
- HWANG KW, SWEATT WB, BROWN IE et al.: Targeted ligation of CTLA-4 in vivo by membrane-bound anti-CTLA-4 antibody prevents rejection of allogeneic cells. .1. kninunol (2002) 169:633–637.
- OKAZAKI T, IWAI Y, HONJO T: New regulatory co-receptors: inducible costimulator and PD-1. Can: Opin. kninunol (2002) 14:779–782.
- OZKAYNAK E, WANG L, GOODEARL A et al.: Programmed death-1 targeting can promote allograft survival.' kninunol (2002) 169:6546–6553.
- NEZNANOV N, NEZNANOVA L, KONDRATOV RV et al.: Dominant negative form of signal-regulatory protein-a (SIRPa /SHPS-1) inhibits tumor necrosis factor-mediated apoptosis by activation of NF-icB. I Biol. Chem. (2003) 278:3809–3815.
- TRIDANDAPANI S, SIEFKER K, TEILLAUD JL et al.: Regulated expression and inhibitory function of FcyRIIb in human monocytic cells..! Biol. Chem. (2002) 277:5082–5089.
- CHANG CC, CIUBOTARIU R, MANAVALAN JS et al.: Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4. Nat. Innnunol. (2002) 3:237–243.
- LIANG S, BAIBAKOV B, HORUZSKO A: HLA-G inhibits the functions of murine dendritic cells via the PIR-B immune inhibitory receptor. Ear: j kninunol (2002) 32:2418–2426.
- MCQUEEN KL, PARHAM P: Variable receptors controlling activation and inhibition of NK cells. Can: Opin. Innnunol. (2002) 14:615-621. Patents