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Review

Protein tyrosine kinase inhibitors as anticancer agents

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Pages 35-53 | Published online: 02 Mar 2005

Bibliography

  • SUN L, MCMAHON G: Inhibition of tumor angiogenesis by synthetic receptor tyrosine kinase inhibitors. Drug Dev. Today (2000) 5:344–353.
  • FABBRO D, PARKINSON D, MATTER A: Protein tyrosine kinase inhibitors: new treatment modalities ? Curr. Opin. Phannacoi (2002) 2:374–381.
  • ••Excellent review on the development ofimatinib.
  • LEVITZKI A: Tyrosine kinases as targets for cancer therapy. Eur. Cancer. (2002) 38 (Supp1.5):S11–S18.
  • LEE AV, SCHIFF R, CUI X et al.: New mechanisms of signal transduction inhibitor action: receptor tyrosine kinase down-regulation and blockade of signal transactivation. Clin. Cancer Res. (2003) 9:516S–523S.
  • RITTER CA, ARTEAGA CL: The epidermal growth factor receptor-tyrosine kinase: a promising therapeutic target in solid tumors. Semin. Oncol. (2003) 30\(Supp1.1):3–11.
  • •Good review on EGFR TK inhibitors.
  • CROOM KF, PERRY CM: Imatinib mesylate: in the treatment of gastrointestinal stromal tumours. Drugs (2003) 63:513–522.
  • DREVS J, MEDINGER M, SCHMIDT-GERSBACH C, WEBER R, UNGER C: Receptor tyrosine kinases: the main targets for new anticancer therapy. Curr. Drug Targets (2003) 4:113–121.
  • MANLEY PW, COWAN-JACOB SW, BUCHDUNGER E et al.: Imatinib: a selective tyrosine kinase inhibitor. Eur. Cancer (2002) 38 (Supp1.5):S19–S27.
  • HUBBARD SR: Protein tyrosine kinases: autoregulation and small-molecule inhibition. Curt: Opin. Struct. Biol. (2002) 12:735–741.
  • SATTLER M, PRIDE YB, MA P et al.:A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase. Cancer Res. (2003) 63:5462–5469.
  • GEORGE D: Targeting PDGF receptors incancer-rationales and proof of concept clinical trials. Adv. Exp. Med. Biol. (2003) 532:141–151.
  • SATTLER M, SCHEIJEN B, WEISBERG E, GRIFFIN JD: Mutated tyrosine kinases as therapeutic targets in myeloid leukemias. Adv. Exp. Med. Biol. (2003) 532:121–140.
  • DRUKER BJ, TALPAZ M, RESTA DJ et al.: Efficacy and safety of a specific inhibitor of the Bcr-Abl tyrosine kinase in chronic myeloid leukemia. N Engl. I Med. (2001) 344:1031–1037.
  • TALPAZ M, SILVER RT, DRUKER BJ et al.: Gleevec induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a Phase II study. Blood (2002) 99:1928–1937.
  • THIESING JT, OHNO-JONES S, KOLIBABA KS, DRUKER BJ: Efficacy of STI-571, an ABL tyrosine kinase inhibitor, in conjunction with other antileukemic agents against Bcr-Abl-positive cells. Blood (2000) 96:3195–3199.
  • BONOMI P: Clinical studies with non-Iressa EGFR tyrosine kinase inhibitors. Lung Cancer (2003) 41\(Supp1.1):S43–S48.
  • SCHUENEMAN AJ, HIMMELFARB E, GENG L et al.: SU-11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res. (2003) 63:4009–4016.
  • WAKELING AE: Epidermal growth factor receptor tyrosine kinase inhibitors. Curl: Opin. Pharmacol (2002) 2:382–387.
  • •Up-to-date and interesting review.
  • BONOMI P: Erlotinib: a new therapeutic approach for non-small cell lung cancer. Expert Opin. Investig. Drugs. (2003) 12:1395–1401.
  • WANG Y, METCALF CA, SHAKESPEARE WC et al.: Bone-targeted 2,6,9-trisubstituted purines: novel inhibitors of Src tyrosine kinase for the treatment of bone diseases. Bioorg. Med. Chem. Lett. (2003) 13:3067–3070.
  • RACHID Z, BRAHIMI F, KATSOULAS A, TEOH N, JEAN-CLAUDE BJ: The combi-targeting concept: chemical dissection of the dual targeting properties of a series of `combi-triazenes'. Med. Chem. (2003) 46:4313–4321.
  • CIARDIELLO F, CAPUTO R, BIANCO R et al.: Inhibition of growth factor production and angiogenesis in human cancer cells by ZD-1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor. Clin. Cancer. Res. (2001) 7: 14 5 9–1 46 5 .
  • RANSON M, HAMMOND LA, FERRY D et al.: ZD-1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: results of a Phase I trial.' Clin. Oncol (2002) 20:2240–2250.
  • DREVS J, SCHMIDT-GERSBACH C, MROSS K et al.: Surrogate markers for the assessment of biological activity of the VEGF-receptor inhibitor PTK-787/ ZK-222584 (PTK/ZK) in two clinical Phase I trials. Proc. ASCO (2002) 85a:Abstract 337.

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