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Review

Inhibitors of sodium-dependent phosphate transport

Pages 81-84 | Published online: 02 Mar 2005

Bibliography

  • EDWARDS RM: Disorders of phosphate metabolism in chronic renal disease. Curc Opin. Phannoc. (2002) 2:171–176.
  • •A detailed review of the pathological consequences of hyperphosphatemia, the mechanism of phosphate handling by epithelial sodium-dependent phosphate transporters, and current and potential therapeutic approaches to limiting serum phosphate levels.
  • HUTCHISON A, WEBSTER I, GILL M et al.: Safety, tolerability and efficacy of lanthanum carbonate in haemodialysis patients: a 12-month study. The ERA-EDTA World Congress of Nephrology Berlin, Germany (2003).
  • GENZYME CORP.: Renagel tablets. In: Physicians Desk Reference, 57th Edition. Thomson PDR (Ed.), Montvale, NJ, USA (2003):1419–1421.
  • FIELD JA, ZHANG L, BRUN KA et al.: Cloning and functional characterization of a sodium-dependent phosphate transporter expressed in human lung and small intestine. Biochem. Biophys. Res. Commun. (1999) 258:578–582.
  • FRANZ RG, GAITANOPOULOS D, GIRARD GR et al.: Inhibitors of phosphate transport. 225th ACS Meeting. New Orleans, USA (2003). MEDI 298.
  • •This poster gives detailed inhibition data for several series of potent sodium-dependent phosphate transporters.

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