Advanced search
Publication Cover
Expert Opinion on Therapeutic Patents Volume 17, 2007 - Issue 8
Submit an article Journal homepage
55
Views
10
CrossRef citations to date
0
Altmetric
Editorial

Efflux pump inhibitors in bacteria

Sandrine Alibert Université de la Méditerranée, Facultés de Médecine et de Pharmacie, UMR-MD1: Enveloppe Bactérienne, Perméabilité & Antibiotiques, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France +33 4 91 83 55 38; +33 4 91 32 46 06; [email protected]
&
Jean-Marie Pagès Université de la Méditerranée, Facultés de Médecine et de Pharmacie, UMR-MD1: Enveloppe Bactérienne, Perméabilité & Antibiotiques, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France +33 4 91 83 55 38; +33 4 91 32 46 06; [email protected]
Pages 883-888 | Published online: 16 Aug 2007

Bibliography

  • PIDDOCK LJV: Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria. Clin. Microbiol. Rev. (2006) 19(2):382-402.
  • LOMOVSKAYA O, BOSTIAN K: Practical applications and feasibility of efflux pump inhibitors in the clinic – a vision for applied use. Biochem. Pharm. (2006) 71(7):910-918.
  • MAHAMOUD A, CHEVALIER J, ALIBERT-FRANCO S, KERN WV, PAGèS JM: Antibiotic efflux pumps in Gram-negative bacteria: the inhibitor response strategy. J. Antimicrob. Chemother. (2007) 59(6):1223-1229.
  • CHANG AB, LIN R, KEITH SW et al.: Phylogeny as a guide to structure and function of membrane transport proteins. Mol. Membr. Biol. (2004) 21(3):171-181.
  • MARKHAM PN, WESTHAUS E, KLYACHKO K, JOHNSON ME, NEYFAKH AA: Multiple novel inhibitors of the NorA multidrug transporter of Staphylococcus aureus. Antimicrob. Agents Chemother. (1999) 43(10):2404-2408.
  • MALLÉA M, MAHAMOUD A, CHEVALIER et al.: Alkylaminoquinolines inhibit bacterial antibiotic efflux pump in multidrug-resistant clinical isolates. Biochem. J. (2003) 376(3):1-5.
  • MULLIN S, MANI N, GROSSMAN TH: Inhibition of antibiotic efflux in bacteria by the novel multidrug resistance inhibitors Biricodar (VX-710) and Timcodar (VX-853). Antimicrob. Agents Chemother. (2004) 48(11):4171-4176.
  • WATKINS W, LANDAVERRY Y, LÉGER R et al.: The relationship between physicochemical properties, in vitro activity and pharmacokinetic profiles of analogues of diamine-containing efflux pump inhibitors. Bioorg. Med. Chem. Lett. (2003) 13(23):4241-4244.
  • VAN BAMBEKE F, PAGÈS J-M, LEE VJ: Inhibitors of bacterial efflux as adjuvants in antibiotic treatments and diagnostic tools for detection of resistance by efflux. Recent Patents on Anti-Infective Drug Discovery (2006) 1:157-175.

Patents

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.