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Current Opinion on Therapeutic Patents Volume 2, 1992 - Issue 1
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Cardiovascular Agents (Including Blood Products)

Patent Update: Bile Acid Sequestrants: Recent Patent Applications

Deirdre MB Hickey Atherosclerosis Programme, SmithKline Beecham Pharmaceuticals, The Frythe, Welwyn, Herts, AL6 9AR, UK
&
G Martin Benson Atherosclerosis Programme, SmithKline Beecham Pharmaceuticals, The Frythe, Welwyn, Herts, AL6 9AR, UK
Pages 73-81 | Published online: 02 Mar 2011

References to Primary Literature

  • Hunninghake, DB Bile-acid seqnestrant therapy. J. Drug Dev. 1990 3 Suppl 1 205–209.
  • Snyder, S Comparison of cholesterol-lowering regimens. Am. Fam. Physician 1990 42 761–768.
  • Ast, M Frishman, WH Bile acid sequestrants. J. Clin. Pharmacol 1990 30 99–106.
  • Zavoral, JH Kwiterovich, PO Marquis, NR Hutton, GD Kafonek, SD Comparative efficacy of cholestyramine tablets and powder. Arteriosclerosis 1990 10 801a.
  • Lipid Research Clinics Program The lipid research clinics coronary primary prevention trial results. I. Redaction in incidence of coronary heart disease. J. Am. Med. Assoc. 1984 251 351–364.
  • Lipid Research Clinics Program The lipid research clinics coronary primary prevention trial results. II. The relationship of redaction in incidence of coronary heart disease to cholesterol lowering. J. Am. Med. Assoc. 1984 251 365–374.
  • Chandler, CE Harwood, HJ Jr Wilkins, RW Pellarin, LD Bangerter, FW Cosgrove, PG Mikolay, L Zaccaro, L Comparison of the effects of CP-88488, cholestyramine and colestipol on cholesterol metabolism in the hamster. X International Symposium on Drugs Affecting Lipid Metabolism Houston, US 1989 A419.
  • Harwood, HJ Chandler, CE Wilkjns, RW Pellarin, ID Bangerter, FW Cosgrove, PG Mikolay, L Zaccaro, L Effects of the soluble bile acid sequestrant, CP-88488, on cholesterol metabolism in mice, rats and hamsters X International Symposium on Drugs Affecting Lipid Metabolism Houston, US 1989 A418.
  • Bangerter, FW Mikolay Chandler, CE Comparison of in vitro bile acid binding by CP-88488 and other bile acid sequestrants. X International Symposium on Drugs Affecting Lipid Metabolism Houston, US 1989 A652.
  • Benson, GM Haynesc Glen, A Blanchard, S Cresswell, S Alston, DR Hickey, DMB Suckling, KE In vitro bile acid binding properties of SK&F 97426-A and cholestyramine. 9th International Symposium on Atherosclerosis Chicago, US 1991 A86 182.
  • Benson, GM Haynes, C Gee, A Jackson, B Glen, A Roberts, M Alston, DR Hickey, DMB Bond, B Suckling, KE SK&F 97426-A a more potent bile acid sequestrant and hypocholesterolaemic agent than cholestyramine in the hamster. 9th International Symposium on Atherosclerosis Chicago, US 1991 A85 181.
  • Witztum, JL Intensive drug therapy of hypercholesterolaemia. Am. Heart J. 1987 113 603–609.
  • O'Brien, RC Simons, LA Clifton, P Cooper, ME Jennings, GL Jerums, G Nestel, PJ Sullivan, D Med. J. Aust. 1990 152 480–483.
  • Vega, GL Grundy, SM Treatment of primary moderate hypercholesterolemia with lovastatin (mevinolin) and colestipol. J. Am. Med. Assoc. 1987 257 33–38.
  • Leren, TP Hjermann, I Berg, K Leren, P Foss, OP Viksmoen, L Effects of lovastatin alone and in combination with cholestyramine on serum lipids and apolipoproteins in heterozygotes for familial hypercholesterolemia. Atherosclerosis 1988 73 135–141.
  • Erkelensdw Baggen, MGA Van Doormaal, JJ Kettner, M Koningsberger, JC Mol, MJTM Drugs 1988 36 Suppl. 3 87–92.
  • Molgaard, J von Schenck, H Olsson, AG Comparative effects of simvastatin and cholestyramine in treatment of patients with hypercholesterolaemia. Eur. J. Clin. Pharmacol. 1989 36 455–460.
  • Bristol-Myers Company EP -387885-A 16 Mar 1989.

References to Patent literature

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