6
Views
2
CrossRef citations to date
0
Altmetric
Anticancers, Hormonals & Metabolic Disease Therapy

Overview: Inhibitors of Bone Resorption and Implications for Therapy

, , , , , , , & show all
Pages 1517-1538 | Published online: 02 Mar 2011

References to Primary Literature

  • Gotfredsen, A Nilas, L RiiS, BJ Christiansen, C Bone changes occuring spontaneously and caused by oestrogen postmenopausal women: A local or generalized phenomenon? Br. M. J. 1986 292 1098–1100.
  • Riis, BJ Christiansen, C Measurement of spinal or peripheral bone mass to estimate early postmenopausal bone loss? Am. J. M. 1988 84 646–653.
  • Christiansen, C Christiansen, MS McNair, P Hagen, C Stocklund, K-E Transbol, I Postmenopausal bone loss: Controlled 2-year study in 315 normal females. Eur. J. Clin. Invest. 1980 10 273–279.
  • Christiansen, C Christiansen, MS Transbol, I Bone mass in postmenopausal women after withdrawal of oestrogen/gestagen replacement therapy. Lancet 1981 i 459–461.
  • Hammond, CB Maxson, WS Current status of estrogen therapy. Fertil. Steril. 1982 37 5–25.
  • Maschchak, CA Lobo, RA Dozono-Takono, R Eggena, P Nakamura, RM Brenner, PF Mishell, DR Comparison of pharmacodynamic properties of various estrogen formulations. Am. J. Obstet. Gynecol. 1982 144 511–518.
  • Hammond, CB Maxson, WS Estrogen replacement therapy. Clin. Obstet. Gynecol. 1986.
  • Teitelbaum, SL Kahn, TJ Mononuclear phagocytes, osteoclasts and bone resorption. Miner. Electrolyte Metab. 1980 3 2–7.
  • Stevenson, JC Abeyasekera, G Hillyard, CJ Phang, KG MacIntyre, I Campbell, S Lane, G Townsend, PT Young, O Whitehead, MI Regulation of calcium regulating hormones by exogenous sex steroids in early post menopause. Eur. J. Clin. Invest. 1983 13 481–487.
  • Selby, PL Oestrogens and bone Osteoporosis, pathogenesis and management Francis, RM Kluwer Academic Publishers 1990 81–102.
  • Eriksen, EF Colvard, DS Berg, NJ Graham, ML Mann, KG Spelsberg, TC Riggs, BL Evidence of estrogen receptors in normal human osteoblasts-like cells. Science 1988 241 84–86.
  • Lin, HY Harris, TL Flannery, NS Aruffo, A Kajiehgorn, A Kolakowski, LF Jr Lodish, HF Goldring, SR Expression cloning of an adenylate cyclase-coupled calcitonin receptor. Science 1991 254 1022–1024.
  • Gray, TK Flyn, TC Gray, KM Nabell, LM 17β-estradiol acts directly on the clonal osteoblast line UMR 106. Proc. Natl. Acad. Sci. USA 1987 84 6267–6271.
  • Ernst, M Heath, JK Rodan, GA Estradiol effects on proliferation, messenger ribonucleic acid for collagen and insulin-like growth factor-I, and parathyroid hormone-stimulated adenylate cyclase activity in osteoblastic cells from calvariae and long bones. Endocrinology 1989 125 825–833.
  • Tabibzadeh, SS Santhanan, U May, L Sehgal, P Cytokine-induced production of IFN-β2/IL-6 by freshly explanted human endometrial stroma cells: Modulation by oestradiol-17β. J. Immunol. 1989 142 3134–3139.
  • Girasole, G Jilka, RL Passeri, G Boswell, S Boder, G Williams, DC Manolagas, SC 17β-Estradiol inhibits interleukin-6 production by bone marrow stromal derived stromal cells and osteoblasts in vitro: A potential mechanism for the antiosteoporotic effect of estrogen. J. Clin. Invest. 1992 In press.
  • Rickard, D Russell, G Gowen, M Oestradiol inhibits the release of tumor necrosis factor but not interleukin 6 from adult human osteoblasts in vitro. Osteoporosis Int. 1992 2 94–102.
  • Pacifici, R Rifas, L McCracken, R Vered, I McMurtry, C Avioli, LV Peck, WA Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin-1 release. Proc. Natl. Acad. Sci. USA 1989 86 2398–2402.
  • Ralston, SH Russell, RGG Gowen, M Oestrogen inhibits release of tumor necrosis factor from peripheral blood mononuclear cells in postmenopausal women. J. Bone Miner. Res. 1990 983–988.
  • Turner, RT Colvard, DS Spelsberg, TC Estrogen inhibition of periosteal bone formation in rat long bones: Down-regulation of gene expression for bone matrix proteins. Endocrinology 1990 127 1346–1351.
  • MacIntyre, I Stevenson, JC Whitehead, MI Wimalawansa, SJ Banks, LM Healy, MJL Calcitonin for prevention of postmenopausal bone loss. Lancet 1988 1 900–2.
  • Gruber, HE Ivey, JL Baylink, DJ Matthew, SM Nelp, WB Sosom, K Chestnut, CH Long term calcitonin therapy in postmenopausal osteoporosis. Metabolism 1988 33 295–303.
  • Zaidi, M Moonga, BS Bevis, PJR Bascal, ZA Breimer, LH Calcitonin gene peptides: Biology and clinical relevance. Critical Reviews in Clinical and Laboratory Sciences 1990 28 109–174.
  • Pecile, A Calcitonin and relief of pain. Bone Miner. 1992 16 187–189.
  • Seiber, P Brugger, M Kamber, P Riniker, B Rittel, W Menschliches calcitonin. III. Die synthese von calcitonin M. Helv. Chim. Acta 1986 51 2057–2061.
  • Maier, R Riniker, B Rittel, W Analogues of human calcitonin. I. Influence of modification in amino acid positions 29 and 31 and hypocalcaemic activity in the rat. FEBS Lett. 1974 48 68–71.
  • Epand, RM Epand, RF Orlowski, RC Seyler, JK Colescott, RL Conformational flexibility and biological activity of salmon calcitonin. Biochemistry 1986 25 1964–1968.
  • Galante, L Horton, R Joplin, GF Woodhouse, NJF MacIntyre, I Comparison of human porcine and salmon synthetic calcitonins in man and in the rat. Clin. Sci. 1971 40 9–10.
  • Epand, RM Epand, RF Orlowski, RC Lanigan, E Stahl, GL A comparison of the interaction of glucagon, human parathyroid hormone -(1–34)-peptide and calcitonin with dimyristoylphosphatidyl-glycerol and with dimyristoylphosphatidylcholine. Biophys. Chem. 1985 23 39.
  • Pless, J Bauer, W Bossert, H Zehnder, K Guttmann, ST Endocrinology Proc. Third Int. Symposium 1971 William Heinemann Medical Books London 67.
  • Tanuichi, H The impact of protein chemistry on Biomedical Sciences Schechter, AN, Dean, A, Goldberg, RF Academic Press Orlando, FL 1984 67.
  • Manning, M Przybylski, A Olma, A Klis, WA Kruszynski, M Wo, NC Pelton, GH Sawyer, WH No requirements of cyclic conformation of antagonists in binding to vasopressin receptors. Nature 1987 329 839–840.
  • Schwarrtz, KE Orlowski, RC Marcus, R des-Ser2 salmon calcitonin: A biologically potent synthetic analog. Endocrinology 1981 108 831–835.
  • Morikawa, T Muniketa, E Sakakibara, S Noda, T Otani, M Synthesis of Eel-calcitonin and [Asu1,7]-Eel-calcitonin: Contribution of the disulfide bond to the hormonal activity. Experientia 1976 32 1104–1106.
  • Zaidi, M Chambers, TJ Gaines Das, RE Morris, HR MacIntyre, I A direct effect of human calcitonin gene-related peptide on isolated osteoclasts. J. Endocrinol. 1987 115 511–518.
  • Orlowski, RC Epand, RM Stafford, AR Biologically potent analogues of salmon calcitonin which do not contain an N-terminal disulfide-bridged ring structure. Eur. J. Biochem. 1987 162 399–402.
  • Agus, ZS Wasserstein, S Goldfarb, S PTH, calcitonin cyclic nucleotides and the kidney. Annu. Rev. Physiol. 1981 43 583–595.
  • MacIntyre, I Parsons, JA Robinson, CJ The effect of thyrocalcitonin on blood bone calcium equilibrium in the perfused tibiae of the cat. J. Physiol. 1967 191 393–405.
  • Aliopoulious, MA Gildhaber, P Munson, PL Thyrocalcitonin inhibition of bone resorption induced by parathyroid hormone in tissue culture. Science 1965 151 330–331.
  • Freidman, J Raisz, LG Thyrocalcitonin: Inhibitor of bone resorption in tissue culture. Science 1965 150 1465–1467.
  • Milhaud, G Perault, AM Moukhtar, MS Etude du mecanisme de l'action hypocalcemiante de la thyrocalcitonine. CR Academy of Science Paris 1965 D261 813.
  • Robinson, CJ Martin, TJ Mathews, EW MacIntyre, I Mode of action of thyrocalcitonin. J. Endocrinol. 1967 39 71–79.
  • Reynolds, JJ Dingle, JT Gudmundsson, TV MacIntyre, I Bone resorption in vitro and its inhibition by calcitonin. Calcitonin, Proc. Int. Symposium on Thyrocalcitonin and C-cells 1968 Taylor, SF Heinemann London 223.
  • Holtrop, NE Raisz, LJ Simmons, HA The effects of parathyroid hormone, colchicine and calcitonin on the ultrastructure and the activity of osteoclasts in organ culture. J. Cell Biol. 1974 60 346–355.
  • Kallio, DM Garant, PR Minkin, C Ultrastructural effects of calcitonin on osteoclasts in tissue culture. J. Ultrastruct. Res. 1972 39 205–216.
  • MacIntyre, I Alevizaki, M Bevis, PJR Zaidi, M Calcitonin and peptides from the calcitonin genes. Clin. Orthop. 1987 21 45.
  • Chambers, TJ Magnus, CJ Calcitonin alters behaviour of isolated osteoclasts. J. Pathol. 1982 136 27–39.
  • Chambers, TJ McSheehy, PMJ Thomson, BM Fuller, K The effect of calcium regulating hormones and prostaglandins on bone resorption by osteoclasts disaggregated from rabbit long bones. Endocrinology 1985 116 234–239.
  • Chambers, TJ Fuller, K McSheehy, PMJ Pringle, JAS The effect of calcium regulating hormones on bone resorption by isolated osteoclastoma cells. J. Pathol. 1985 145 297–305.
  • Zaidi, M Fuller, K Bevis, PJR Gaines Das, RE Chambers, TJ MacIntyre, I Calcitonin gene-related peptide inhibits osteoclastic bone resorption: A comparative study. Calcif. Tissue Int. 1987 40 149–154.
  • Zaidi, M Breimer, LH MacIntyre, I The biology of the peptides from the calcitonin genes. Q. J. Exp. Physiol. 1987 72 371–408.
  • Zaidi, M Chambers, TJ Bevis, PJR Beacham, JL Gaines Das, RE MacIntyre, I Effects of peptides from the calcitonin genes on bone and bone cells. Q. J. Exp. Physiol. 1988 73 471–485.
  • Chambers, TJ Fuller, K Darby, JA Hormonal regulation of acid phosphatase release by osteoclasts disaggregated from neonatal rat bone. J. Cell Physiol. 1987 132 92–96.
  • Moonga, BS Moss, DW Patchell, A Zaidi, M Intracellular regulation of enzyme release from rat osteoclasts and evidence for a functional role in bone resorption. J. Physiol. 1990 429 29–45.
  • Akisaka, T Gay, CV Ultracytochemical evidence for a proton-pump adenosine triphosphatase in chick osteoclasts. Cell Tissue Res. 1986 245 507–512.
  • Anderson, RE Schraer, H Gay, CV Ultrastructural immunocytochemical localisation of carbonic anhydrase in normal and calcitonin-treated chick osteoclasts. Anat. Rec. 1982 204 9.
  • Nicholson, CG Moseley, JM Sexton, PM Mendelson, FAO Martin, TJ Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterisation. J. Clin. Invest. 1986 78 355–360.
  • Lin, HY Harris, TL Flannery, NS Aruffo, A Kajiehgorn, A Kolakowski, LF Jr Lodish, HF Goldring, SR Expression cloning of an adenylate cyclase-coupled calcitonin receptor. Science 1991 254 1022–1024.
  • Juppner, H Abou-Sanra, A-B Freeman, M Kong, FX Schipani, E Richards, J Kolakowski, LF Jr Hock, J Potts, JT Jr Kronenberg, HM Segre, GV A G protein linked receptor for parathyroid hormone-related peptide. Science 1991 254 1024–1026.
  • Chakarborty, M Chatterji, D Kellokumpus, SH Baron, R Cell dependent coupling of calcitonin receptor to different G proteins. Science 1991 251 1078–1081.
  • Zaidi, M Datta, HK Moonga, BS MacIntyre, I Evidence that the action of calcitonin on rat osteoclasts is mediated by two G proteins acting via separate post-receptor pathways. J. Endocrinol. 1990 126 473–481.
  • Zaidi, M Datta, HK Bevis, PJR Wimalawansa, SJ MacIntyre, I Amylin amide: A new bone-conserving peptide from the pancreas. Exp. Physiol. 1990 75 529–536.
  • Alam, ASMT Moonga, BS Bevis, PJR Huang, CLH Zaidi, M Selective antagonism of calcitonin-induced osteoclastic quiescence (Q effect) by human calcitonin gene-related peptide (Val8Phe37). Biochem. Biophys. Commun. 1991 179 134–139.
  • Fleisch, H Bisphosphonates: Pharmacology and use in the treatment of tumor-induced hypercalcaemic and metastatic bone disease. Drugs 1991 42 919–944.
  • Fleisch, H Russell, RGG Fransis, MD Diphosphonate inhibits the hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo. Science 1969 165 1262–1264.
  • Russell, RGG Bisaz, S Donath, A Fleisch, H Inorganic pyrophosphate in plasma in normal persons and in patients with hypophosatasia, osteogenesis imperfecta and other disorders of bone. J. Clin. Invest. 1971 961–969.
  • Shinoda, H Adamek, G Felix, R Fleisch, H Schenk, R Hagan, P Structure activity relationships of various bisphosphonates. Calcif. Tissue. Int. 1983 35 87–99.
  • Bijvoet, OLM Hosking, DJ Lemkes, HHPJ Reitsma, PH Frulink, WB Development in the treatment of Paget's disease Endocrinology of calcium metabolism. Copp, Excerpta Medica Amsterdam/Oxford 1978 421 48–54.
  • Reitsma, PH Bijvoet, OLM Verlinden Ooms, H Van der Wee-Pals, LJA Kinetic studies of bone and mineral metabolism during treatment with (3-amino-1-hydroxypropylidene)-1,1-bisphosphonate (APD) in rats. Calcif. Tissue Int. 1980 32 145–147.
  • Schenk, R Eggli, P Felix, R Fleisch, H Rosini, S Quantitative morphometric evaluation of the inhibitory activity of new amino-bisphosphonates on bone resorption in the rat. Calcif. Tissue Int. 1986 38 342–349.
  • Boonekamp, PM Lowik, CWGM Van der Wee-Pals, LJA Van Wijk-Van Lennep, MLL Bijvoet, OLM Enhancement of the inhibitory action of APD on the transformation of osteoclast precursors into resorbing cells after dimethylation of the amino group. Bone Miner. 1987 2 29–42.
  • Muhlbauer, RC Stutzer, A Schenk, R Janner, M Fleisch, H 1-Hydroxy-3-(methyl-pentylamino) propylidene-bisphosphonate (BM 21.0955), a potent new inhibitor of bone resorption. J. Bone Miner. Res. 1989 4 Suppl 1 S168.
  • Muhlbauer, RC Bauss, F Schenk, R Janner, M Bosies, E Strein, K Fleisch, H BM 21.0955, a potent new bisphosphonate to inhibit bone resorption. J. Bone. Miner. Res. 1991 6 1003–1011.
  • Bevan, JA Johnson, KY Slough, C Benedict, N Fleisch, H Skeletal effects of 2-(2-pyridinyl)-ethylidene-bisphosphonate in acute and subchronic rat studies. Calcif. Tissue Int. 1986 38 531.
  • Bevan, JA Franks, AF McOsker, JE Boyce, RW Buckingham, KW Bisphosphonate action in the oophorectomized rat: The effects of 2-(-pyridinyl)-1-hydroxyethlidenebis(phosphonate) on skeletal metabolism; comparison with etidronate. J. Bone Miner. Res. 1988 3 Suppl 1 S193.
  • Sietsema, WK Ebetino, FH Salvagno, AM Bevan, JA Antiresorptive dose-response relationship across three generations of bis-phosphonates. Drugs Exp. Clin. Res. 1989 15 389–396.
  • Fleisch, H Bisphosphonates: Mechanisms of action and clinical application Bone and mineral research. Annual 1 Peck, WA Amsterdam Oxford-Princeton, Excerpta Medica 1983 319–357.
  • Monkkonen, JA One year follow up study of the distribution of 14C-clodronate in mice and rats. Pharmacol. Toxicol. 1988 62 5153.
  • Powell, JH De Mark, BP Clinical pharmacokinetics of diphosphonates Bone resorption metastasis, and diphosphonates Garrafini, S Raven Press New York 1985 41–49.
  • Muhlbauer, RC Fleisch, H A method for continual monitoring of bone resorption in rats: Evidence for a diurnal rhythm. Am. J. Physiol. 1990 259 R679–R689.
  • Stutzer, A Fleisch, H Trechsel, U Shortand long-term effects of a single dose of bisphosphonates on retinoid-induced bone resorption in thyroparathyroidectomised rats. Calcif. Tissue Int. 1988 43 294–299.
  • Thiebaud, D Jeager, P Burcckhardt, P A single-day treatment of tumor-induced hypercalcaemia by intravenous amino hydroxypropylidene bisphosphonate. J. Bone Miner. Res. 1986 1 555–562.
  • Fast, DK Felix, R Dowse, C Neuman, WF Fleisch, H The effects of bisphosphonates on the growth and glycolysis of connective-tissue cells in culture. Biochem. J. 1978 172 97–107.
  • Felix, R Guenther, HL Fleisch, H The subcellular distribution of 14C dichloromethylene-bisphosphonate and 14C 1-hydroxy-eth-1,1-bisphosphonate in cultured calvaria cells. Calcif. Tissue Int. 1984 36 108–13.
  • Flanagan, AM Chambers, TJ Dichloromethylenebisphosphonate (Cl2MBP) inhibits bone resorption through injury to osteoclasts that resorb Cl2MBP-coated bone. Bone Miner. 1989 6 33–43.
  • Felix, R Russell, RGG Fleisch, H The effect of several bisphosphonates on acid phosphohydrolases and other lysosomal enzymes. Biochimica et Biophysica Acta 1976 429 429–438.
  • Smirnova, IN Kudryavtseva, NA Komissarenko, SV Tarusova, NB Baykov, AA Bisphosphonates are potent inhibitors of mammalian inorganic pyrophosphatase. Arch. Biochem. Biophys. 1988 267 280–84.
  • Felix, R Bettex, JD Fleisch, H Effect of bisphosphonates on the synthesis of prostaglandins in cultured calvaria cells. Calcif. Tissue Int. 1981 33 549–552.
  • Carano, A Teitelbaum, SL Konsek, JD Schlesinger, PH Blair, HC Bisphosphonates directly inhibit the bone resorption activity of isolated avian osteoclasts in vitro. J. Clin. Invest. 1990 85 456–461.
  • Valkema, R Visman, SF-JFE Papapoulos, SE Effects of long term low dose bisphosphonate (APD) on calcium balance and bone mineral content in patients with osteoporosis. Bone Min. 1989 5 183–192.
  • Reitsma, PH Bijvoet, OL Potokar, M van der Wee-Pals, LJ van Wijk-van Lennep, MM Apposition and resorption of bone during oral treatment with (3-amino-1-hydroxypropylidene)-1,1-bisphosphonate (APD). Calcif. Tissue Int. 1983 35 357–361.
  • Cecchini, MG Felix, R Fleisch, H Cooper, PH Effects of bisphosphonates on proliferation and viability of mouse bone marrow derived macrophages. J. Bone Miner. Res. 1987 2 135–142.
  • Cecchini, MG Fleisch, H Bisphosphonates in vitro specifically inhibit, among the hemopoietic series, the development of the mouse mononuclear phagocyte linege. J. Bone Miner. Res. 1990 5 1019–1027.
  • Martin, TJ Actions of calcitonin and mithramycin. Arthritis and Rheum. 1980 23 1131–1138.
  • Ryan, WC Schwartz, TB Perlia, CP Effects of mithramycin on Paget's disease of bone. Ann. Intern. Med. 1969 70 549–557.
  • Cortes, EP Holland, JF Moskowitz, R Depoli, E Effects of mithramycin on bone resorption in vitro. Cancer Res. 1972 32 7476.
  • Warrell, RP Murphy, WK Schulman, P O'Dwyer, PJ Heller, G A randomized double-blind study of gallium nitrate compared with etidronate for acute control of cancer related hypercalcaemia. J. Clin. Oncol. 1991 9 1467–1475.
  • Tobias, J Chambers, TJ Glucocorticoids impair bone resorptive activity and viability of osteoclasts disaggregated from neonatal rat long bones. Endocrinology 1989 125 1290–1295.
  • Chenu, C Pfeilschifter, J Mundy, GR Roodman, GD Transforming growth factor β inhibits formation of osteoclast-like cells in long-term human marrow cultures. Proc. Natl. Acad. Sci. USA 1988 85 5683–5687.
  • Bentz, H Nathan, RM Rosen, DM Armstrong, RM Thompson, AY Segarini, PR Matthews, MC Dasch, JR Piez, KA Seyedin, SM Purification and characterization of a unique osteoinductive factor from bovine bone. J. Biol. Chem. 1989 5 20805–20810.
  • Takahashi, N Mundy, GR Roodman, GD Recombinant human interferon-γ inhibits formation of human osteoclast-like cells. J. Immunol. 1986 137 3544–3549.
  • Perussia, B Dayton, ET Fanning, V Thiagarjan, P Hoxie, J Trinchieri, G Immune interferon and leucocyte conditioned medium induced normal and leukaemic myeloid cells to differentiate along the monocytic pathway. J. Exp. Med. 1983 158 2058–2080.
  • Weinberg, JB Hobbs, MM Misukonis, MA Recombinant human gamma interferon induces human monocyte polykaryon formation. Proc. Natl. Acad. Sci. USA 1984 81 4554–4557.
  • Alam, ASMT Moonga, BS Huang, CLH Zaidi, M Amylin inhibits bone resorption by a direct effect on the motility of rat osteoclasts. Exp. Physiology 1992 In press.
  • Datta, HK Zaidi, M Wimalawansa, SJ Ghatei, MA Beacham, JL Bloom, SR MacIntyre, I In vivo and in vitro effects of amylin and amylin-amide on calcium metabolism in the rat and rabbit. Biochem. Biophys. Res. Commun. 1989 162 876–881.
  • Zaidi, M Chambers, TJ Moonga, BS Oldoni, T Pasarella, E Soncini, R MacIntyre, I A new approach for calcitonin determination based on target cell responsiveness. J. Endocrinol. Invest. 1990 13 119–126.
  • Gelbey, SG Ghatei, MA Bretherton-Watt, D Zaidi, M Jones, PM Perera, T Beacham, J Girgis, S Bloom, SR Islet amyloid polypeptide (IAPP): Production by osteoblasts cell line and possible role as a paracrine regulator of osteoclast function in man. Clinical Science 1991 81 803–808.
  • Hui, SL Epstein, S Johnston, CC Jr A prospective study of bone mass in patients with Type I diabetes. J. Clin. Endocrinol. Metab. 1985 60 74–80.
  • Zaidi, M Alam, ASMT Shankar, VS Bax, BE Bax, CMR Moonga, BS Bevis, PJR Stevens, C Blake, DR Huang, CL-H Cellular biology of bone resorption. Biol. Rev. 1992 In press.
  • Garrett, IR Boyce, BF Oreffo, RO Bonewald, L Poser, J Mundy, GR Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. J. Clin. Invest. 1990 85 632–639.
  • Key, LL Jr Reis, WL Taylor, RG Hays, BD Pitzer, BR Oxygen derived free radicals in osteoclasts: The specificity and location of the nitroblue tetrazolium reaction. Bone 1990 11 115–119.
  • Oursler, MJ Collin-Osdoby, P Li, L Schmitt, E Osdoby, P Evidence for an immunological and functional relationship between superoxide dismutase and a high molecular weight osteoclast plasma membrane glycoprotein. J. Cell Biochem. 1991 46 331–344.
  • Zaidi, M Datta, HK Patchell, A Moonga, BS MacIntyre, I ‘Calcium-activated’ intracellular calcium elevation: A novel mechanism of osteoclast regulation. Biochem. Biophys. Res. Commun. 1989 163 1461–1465.
  • Malgaroli, A Meldolesi, J Zambonin-Zallonea Teti, A Control of cytosolic free calcium in rat and chicken osteoclasts. J. Biol. Chem. 1989 264 14342–14347.
  • Zaidi, M Calcium ‘receptors’ on eukaryotic cells with special reference to the osteoclast Biosci. Rep. 1990 10 493–507.
  • Datta, HK MacIntyre, I Zaidi, M The effect of ionised calcium on the morphology and function of isolated rat osteoclasts. Biosci. Rep. 1989 9 247–251.
  • Miyauchi, A Hruska, KA Greenfield, EM Duncan, R Alvarez, J Barattolo, R Colucci, S Zambonin-Zallone, A Teitelbaum, SL Teti, A Osteoclast cytosolic calcium, regulated by voltage-gated calcium channels extracellular calcium, controls podosome assembly and bone resorption. J. Cell Biol. 1990 111 2543–2552.
  • Zaidi, M Kerby, J Huang, CL-H Alam, ASMT Rathod, H Chambers, TJ Moonga, BS Divalent cations mimic the inhibitory effect of extracellular ionised calcium on bone resorption by isolated rat osteoclasts: Further evidence for a ‘calcium receptor’. J. Cell Physiol. 1991 149 422–427.
  • Zaidi, M Shankar, VS Bax, CMR Bax, BE Alam, ASMT Banerji, B Bevis, PJR Gill, JS Moonga, BS Huang, CL-H Characterisation of the osteoclast calcium receptor Calcium regulation and bone metabolism. Cohn, DV, Tashjian, AR Jr Elsevier Amsterdam 1992 In press.
  • Shankar, VS Bax, CMR Alam, ASMT Bax, BE Huang, CL-H Zaidi, M The osteoclast Ca2+ receptor is highly sensitive to activation by transition metal cations. Biochem. Biophys. Res. Commun. 1992 In press.
  • Shankar, VS Alam, ASMT Bax, CMR Bax, BE Pazianas, M Huang, CL-H Zaidi, M Activation and inactivation of the osteoclast Ca2+ receptor by the trivalent cation, La3+. Biochem. Biophys. Res. Commun. 1992 In press.
  • Bax, BE Alam, ASMT Banerji, B Bax, CMR Bevis, PJR Stevens, CR Moonga, BS Blake, DR Zaidi, M Stimulation of osteoclastic bone resorption by hydrogen peroxide (H2O2). Biochem. Biophys. Res. Commun. 1992 183 1153–1158.
  • MacIntyre, I Zaidi, M Alam, ASMT Datta, HK Moonga, BS Lidbury, PS Hecker, M Vane Jr Osteoclastic inhibition: An action of nitric oxide not mediated by cyclic GMP. Proc. Natl. Acad. Sci. USA 1991 88 2936–2940.
  • Alam, ASMT Gallagher, A Shankar, VS Ghatei, MA Datta, HK Huang, CLH Moonga, BS Chambers, TJ Bloom, SR Zaidi, M Endothelin inhibits osteoclastic bone resorption by a direct effect on cell motility implications for the vascular control of bone resorption. Endocrinology 1992 130 3617–3624.
  • Roodman, GD Osteoclast differentiation. Crit. Rev. Oral Biol. Med. 1991 2 389–409.
  • McSheehy, PMJ Chambers, TJ Osteoblastlike cells in the presence of parathyroid hormone release soluble factor that stimulates osteoclastic bone resorption. Endocrinology 1986 119 1654–1659.
  • McSheehy, PMJ Chambers, TJ 1, 25-dihydroxyvitamin D3 stimulates rat osteoblastic bone resorption. J. Clin. Invest. 1987 80 425–429.
  • Davies, J Warwick, J Tutty, N Phillip, R Helfrich, M Horton, M The osteoclast functional antigen, implicated in the regulation of bone resorption, is biochemically related to the vitronectin receptor. J. Cell Biol. 1989 109 1817–1826.
  • Horton, MA Davies, J Perspectives: Adhesion receptors in bone. J. Bone Miner. Res. 1989 4 803–808.
  • Simpson, A Horton, MA Expression of the vitronectin receptor during embryonic development: An immunohistological study of the ontogeny of the osteoclast in the rabbit. Br. J. Exp. Pathol. 1989 70 257–265.
  • Webber, D Osdoby, P Hauchka, P Krukowski Correlation of an osteoclast antigen and ruled border on giant cells formed in response to resorbable substrates. J. Bone Miner. Res. 1990 5 401–410.
  • Baron, R Molecular mechanisms of bone resorption by the osteoclast. Anat. Rec. 1989 224 317–324.
  • Parvinen, EK Slot, JW Vaarianen, HK Osteoclast acidifying enzymes, carbonic anhydrase II and H+-K+-ATPase immunogold localisation on ultracryosections. Calcif. Tissue Int. 1987 41 Suppl 2 20.
  • Tuukkanen, J Vaananen, HK Omeprazole, a specific inhibitor of H+-K+-ATPase inhibits bone resorption in vitro. Calcif. Tissue Intern. 1986 38 123–125.
  • Zaidi, M Modularity of osteoclast behaviour and mode-specific inhibition of osteoclast function. Biosci. Rep. 1990 10 547–556.
  • Silver, IA Murrills, RJ Etherington, DJ Microelectrode studies on acid microenvironment beneath adherent macrophages and osteoclasts. Exp. Cell Res. 1988 175 266–276.
  • Donahue, HJ Ijima, K Goligorsky, MS Rubin, CT Rifkin, BR Regulation of cytoplasmic calcium concentration in tetracycline treated osteoclast. J. Bone Min. Res. in press.
  • Juhlin, CR Lundgren, S Johansson, H Lorentzen, Z Rask, L Larsson, E Rastad, J Akerstrom, G Klareskog, L 500-kilodalton calcium sensor regulating cytoplasmic Ca2+ in cytotrophoblast cells of human placenta. J. Biol. Chem. 1990 265 8275–8279.
  • Moonga, BS Datta, HK Bevis, PJR Huang, CL-H MacIntyre, I Zaidi, M Correlates of osteoclast function in the presence of perchlorate ions in the rat. Exp. Physiol. 1991 76 923–933.
  • Zaidi, M MacIntyre, I Datta, HK Intracellular calcium in the control of osteoclast function. II. Paradoxical elevation of cytosolic free calcium by verapamil. Biochem. Biophys. Res. Commun. 1990 167 807–812.
  • Bax, CMR Shankar, VS Huang, CL-H Zaidi, M Is the osteoclast calcium ‘receptor’ a receptor-operated calcium channel. Biochem. Biophys. Res. Commun. 1992 183 619–625.
  • Yang, G Condy, TE Boaro, M Wilkaen, HE Jones, P Nazhat, NB Saadalla-Nazhat, RA Blake, DR Free radical yield from the homolysis of peroxynitrous acid. Free Rad. Biol. Med. 1992 12 327–330.
  • Collin-Osdoby, P Oursler, MJ Webber, D Osdoby, P Osteoclast-specific monoclonal antibodies coupled to magnetic beads provide a rapid and efficient method of purifying avian osteoclasts. J. Bone Min. Res. 1991 6 11353–11365.
  • Selley, ML Bourne, DJ Bartlett, MR Tymms, KE Brook, AS Duffield, AM Ardlie, NG Occurence of (E)-4-hydroxy-2-nonenal in plasma and synovial fluid of patients with rheumatoid arthritis and osteoarthritis. Ann. Rheum. Dis. 1992 51 481–484.
  • Parthasarathy, S Steinbrecher, UP Barnett, J Witzum, JL Steinberg, D Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein. Proc. Natl. Acad. Sci. USA 1985 82 3000–3004.
  • Overgaard, K Hansen, MA Jensen, SB Christiansen, C Effect of salcalcitonin given intranasally on bone mass and fracture rates in established osteoporosis: A dose response study. Br. Med. J. 1992 305 556–561.
  • Rico, H Hernandez, ER Revilla, M Gomez-Castnesana, F Salmon calcitonin reduces vertebral fracture rate in postmenopausal crush fracture syndrome. Bone Miner. 1992 16 131–138.

References to Patent Literature

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.