References to Primary Literature
- Hollstein, U Nonlactam antibiotics Burger's Medicinal Chemistry, 4th Edition Wolff, ME 1979 Part II 173–288.
- Fajer, J The mysteries of porphyrin chemistry. Chem. Ind. 1991 869–873.
- Monoclonal antibodies. Epenetos, AA Chapman and Hall London 1991.
- May, PM Agents acting on passive ion transport Comprehensive Medicinal Chemistry Sammes, PE, Taylor, JB 1990 2 175–192.
- Dougherty, TJ Photosensitizers: Therapy and detection of malignant tumours. Photochem. Photobiol. 1987 45 879–889.
- Bonnett, R A death ray for cancer. New Scientist 1989 55–58.
- Beierwaltes, WH Radioimmunotherapy of cancer: Historical perspectives and prospects for the future Radiolabelled Monoclonal Antibodies for Imaging and Therapy. Srivastava, SC NATO ASI Series Series A: Life Sciences 1988 152 739–768.
- Kohler, G Milstein, C Continuous culture of fused cells secreting antibody of predefined specificity. Nature 1975 256 495–497.
- Boyer, CM Lidor, Y Lottich, SC Bast, RC Jr Antigenic cell surface markers in human solid tumours. Antibody, Immunoconjugates and Radiopharmaceuticals 1988 1 105–162.
- Hinman, LM Wallace, RE Hamann, PR Durr, FE Upeslacis, J Calicheamicin Immunoconjugates: Influence of analog and linker modification on activity in vivo. Antibody, Immunoconjugates and Radiopharmaceuticals 1990 3 59.
- Buchsbaum, DJ Lawrence, TS Tumour therapy with radiolabelled monoclonal antibodies. Antibody, Immunoconjugates and Radiopharmaceuticals 1991 4 245–272.
- Humm, JL Chin, LM Review of experimental methods to determine radiation absorbed dose in radioimmunotherapy. Antibody, Immunoconjugates and Radiopharmaceuticals 1991 4 613–621.
- Davidson, BR Waddington, WA Short, MD Boulos, PB Intraoperative localisation of colorectal cancers using radiolabelled monoclonal antibodies. Br. J. Surg. 1991 78 664–670.
- Parker, D Tumour targeting. Chem. Brit. 1990 942–945.
- Troutner, DE Simon, J Ketring, AR Volkert, W Holmes, RA Complexing of 99mTc with cyclam. J. Nucl. Med. 1980 21 443–448.
- Morphy, JR Parker, D Alexander, R Bains, A Carne, AF Eaton, MAW Harrison, A Millican, A Phipps, A Rhind, SK Titmas, R Weatherby, D Antibody labelling with functionalised cyclam macrocycles. J. Chem. Soc., Chem. Comm. 1988 156–158.
- Adair, JR Baker, TS Bebbington, CR Beeley, NRA Emtage, JS King, DJ Lawson, ADG Millican, TA Mountain, A Owens, RJ Yarranton, GT Engineering monoclonal antibody B72.3 for cancer therapy. Protein Engineering of Antibody Molecules for Prophylactic and Therapeutic Applications in Man. Clark, MR 1992 In Press.
- Rhind, SK Harrison, A Walker, C Morphy, JR Millican, TA Weatherby, D Boden, J Pedley, RB Searle, FA Begent, RHJ Bagshawe, KD Eaton, MAW Parker, D In vivo stability of 99mTc macrocycle-B72.3 immunoconjugate. Antibody, Immunoconjugates and Radiopharmaceuticals 1990 3 55.
- Schwarz, A Steinstraesser, A A novel approach to 99mTc labelled monoclonal antibodies. J. Nucl. Med. 1987 28 721.
- Carrasquillo, JA Krohn, KA Beaumier, P McGuffin, RW Brown, JP Hellstrom, KE Hellstrom, I Larson, SM Diagnosis of and therapy for solid tumours with radiolabelled antibodies and immune fragments. Cancer Treat. Rep. 1984 68 317–328.
- Kasina, S Rao, TN Srinivasan, A Sanderson, JA Fitzner, JN Reno, JM Beaumier, PL Fritzberg, AR Development and biologic evaluation of a kit for preformed chelate 99mTc radiolabelling of an antibody Fab fragment using a diamide dimercaptide chelating agent. J. Nucl. Med. 1991 32 1445–1451.
- Hnatowich, D Layne, WW Childs, RL Lanteigne, D Davis, MA Griffin, TW Doherty, PW Radiolabelling of antibody: A simple and efficient method. Science 1983 220 613–615.
- Hnatowich, DF Griffin, TW Kosciuczyk, C Rusckowski, M Childs, RL Mattis, JA Shealy, D Doherty, PW Pharmacokinetics of an 111In labelled monoclonal antibody in cancer patients. J. Nucl. Med. 1985 26 849–858.
- Broan, CJ Cox, JPL Craig, AS Kataky, R Parker, D Harrison, A Taylor, M Ferguson, G Structure and solution stability of indium and gallium complexes of NOTA and yttrium complexes of DOTA and related ligands: Kinetically stable complexes for use in imaging and radioimmunotherapy. J. Chem. Soc. Perkin II 1991 87–89.
- Craig, AS Parker, D Adams, H Bailey, NA Stability, 71Ga NMR and crystal structure of a neutral gallium(III) complex of 1,4,7-triazacyclononanetriacetate: A potential radiopharmaceutical? J. Chem. Soc. Chem. Comm. 1989 1793–1794.
- Craig, AS Helps, IM Jankowski, KJ Parker, D Beeley, NRA Boyce, BA Eaton, MAW Millican, AT Millar, K Phipps, A Rhind, SK Harrison, A Walker, C Towards tumour imaging with indium-111 labelled macrocycle-antibody conjugates. J. Chem. Soc. Chem. Comm. 1989 794–796.
- Rhind, SK Phipps, A Pedley, RB Boden, J Green, AJ King, DJ Millican, AT Millar, K Boyce, BA Beeley, NRA Eaton, MAW Begent, RHJ Bagshawe, KD Secher, DS Parker, D Tumour imaging with indium-111 macrocycle chimeric B72.3(γ4) antibody conjugates. 5th International Conference on Monoclonal Antibody Immunoconjugates for Cancer San Diego, USA March 15–17 1990.
- Celltech Ltd Unpublished observations.
- Granowska, M Mather, SJ Britton, KE Diagnostic evaluation of 111In and 99mTc radiolabelled monoclonal antibodies in ovarian and colorectal cancer: Correlations with surgery. Nucl. Med. Biol. 1991 18 413–424.
- Broan, CJ Jankowski, KJ Kataky, R Parker, D Synthesis and complex stability of parent and C-functionalised derivatives of 1,4,7-triazacyclononane-1,4,7-tris[methylene(methylphosphinic acid)]: An effective new complexing agent. J. Chem. Soc. Chem. Comm. 1990 1738–1739.
- Wessels, BW Rogus, RD Radionuclide selection and model absorbed dose calculations for radiolabelled tumour associated antibodies. Med. Phys. 1984 11 638–645.
- Adelstein, SJ Kassis, AI Criteria for the selection of radionuclides for radioimmunotherapy Radiolabelled Monoclonal Antibodies for Imaging and Therapy. Srivastava, SC NATO ASI Series Series A: Life Sciences 1988 152 165–176.
- Gansow, OA Brechbiel, MW Pippin, CG McMurry, TJ Lambrecht, R Colcher, D Schlom, J Roselli, M Strand, M Huneke, RB Ruegg, CL Lead and bismuth complexes of functionalised DTPA ligands and of the polyazacycloalkane-N-acetic acid DOTA. Utility for radioimmunoimaging and radioimmunotherapy. Antibody, Immunoconjugates and Radiopharmaceuticals 1991 4 413–425.
- Kumar, K Magerstadt, M Gansow, OA Lead(II) and bismuth(III) complexes of the polyazacycloalkane-N-acetic acids NOTA, DOTA and TETA. J. Chem. Soc. Chem. Comm. 1989 145–146.
- Ruegg, CL Anderson-Berg, WT Brechbiel, MW Mirzadeh, S Gansow, OA Strand, M Improved in vivo stability and tumor targeting of bismuth-labelled antibody. Cancer Res. 1990 50 4221–4226.
- Sharkey, RM Kaltovich, FA Shih, LB Fand, I Govelitz, G Goldenberg, DM Radioimmunotherapy of human colonic cancer xenografts with 90Y labelled monoclonal antibodies to carcinoembryonic antigen. Cancer Res. 1988 48 3270–3275.
- Hnatowich, DJ Chinol, M Siebecker, DA Gionet, M Griffin, T Doherty, PW Hunter, R Kase, KR Patient biodistribution of intra-peritoneally administered 90Y labelled antibody. J. Nucl. Med. 1988 29 1428–1434.
- Cox, JPL Jankowski, KJ Kataky, R Parker, D Beeley, NRA Boyce, BA Eaton, MAW Millican, AT Millar, K Harrison, A Walker, C Synthesis of a kinetically stable yttrium-90 labelled macrocycle-antibody conjugate. J. Chem. Soc. Chem. Comm. 1989 797–798.
- Cox, JPL Craig, AS Helps, IM Jankowski, KJ Parker, D Eaton, MAW Millican, AT Millar, K Beeley, NRA Bocye, BA Synthesis of C- and N-functionalised derivatives of NOTA, DOTA and DTPA: Bifunctional complexing agents for the derivatisation of antibodies. J. Chem. Soc. Perkin. I 1990 2567–2576.
- Harrison, A Walker, CA Parker, D Jankowski, KJ Cox, JPL Craig, AS Randall, AM Sansom, JM Eaton, MAW Beeley, NRA Millican, AT Millar, K Boyce, BA Rhind, SK Turner, A Farnsworth, A The in vivo release of 90Y from cyclic and acyclic ligand-antibody conjugates. Nucl. Med. Biol. 1991 18 469–476.
- Farnsworth, A Turner, A Rhind, SK Millican, AT Millar, K Boyce, BA Beeley, NRA Boden, J Boden, R Pedley, RB Parker, D Comparative biodistributions of 90Y and 111In macrocycle chimeric B72.3 conjugates in a human colon carcinoma xenograft model. J. Nucl. Med. 1991 32 1842.
- Moi, MK Meares, CF Denardo, SJ The peptide way to macrocyclic bifunctional chelating agents: Synthesis of 2-(p-nitrobenzyl)-1,4,7,10-tetraazacyclododecane-N,N',N″,N'″-tetraacetic acid and study of its yttrium (III) complex. J. Amer. Chem. Soc. 1988 110 6266–6267.
- Snook, DE Rowlinson-Busza, G Meares, C Epenetos, AA Indium-111 and yttrium-90 labelled macrocyclic chelating agents Monoclonal antibodies. Epenetos, AA Chapman and Hall London 1991 157–166.
- Hird, V Snook, D Kosmas, C Dhokia, B Stewart, S Mason, P Lambert, J Meares, C Epenetos, AA Intra-peritoneal radioimmunotherapy with yttrium-90 labelled immunoconjugates Monoclonal antibodies. Epenetos, AA Chapman and Hall London 1991 267–271.
- Hird, V Verhoeyen, M Badley, RA Price, D Snook, D Kosmas, C Gooden, C Bamias, A Meares, C Lavender, JP Epenetos, AA Tumour localisation with a radioactively labelled reshaped human monoclonal antibody. Br. J. Cancer 1991 64 911–914.
- Kosmas, C Snook, D Gooden, CS Courtenay-Luck, NS McCall, MJ Meares, CF Epenetos, AA Development of humoral immune responses against a macrocyclic chelating agent (DOTA) in cancer patients receiving radioimmunoconjugate for imaging and therapy. Cancer Res. 1992 52 904–911.
- Kabachnik, IM Medved', TY Bel'skii, FI Pisareva, SA Synthesis, acid-base and complex forming properties of 1,4,7,10-tetrakis (dihydroxyphosphorylmethyl)-1,4,7,10-tetraazacyclododecane. Izv. Akad. Nauk. SSSR Ser. Khim. 1984 844–849.
- Broan, CJ Cole, E Jankowski, KJ Parker, D Pulukoddy, K Boyce, BA Beeley, NRA Millar, K Millican, AT Synthesis of new macrocyclic amino-phosphinic acid complexing agents and their C- and P-functionalised derivatives for protein linkage. Synthesis 1992 63–68.
- Beeley, NRA Boyce, BA Eaton, MAW Farnsworth, A Howat, D Millar, K Millican, AT Rhind, SK Secher, D Turner, A Harrison, A Randall, A Walker, C Begent, RHJ Boden, J Boden, R Pedley, RB Broan, C Jankowski, K Kataky, R Parker, D Novel phosphinate macrocycles: Bone localisation of 90Y-12N4P4-cB72.3 conjugates 6th International Conference on Monoclonal Antibody Immunoconjugates for Cancer San Diego, USA 1991 28 February-2 March.
- Meares, CF Diril, H Kukis, D McCall, M Rana, T Wellman, A DeNardo, SJ DeNardo, GL Radiochemistry of antibodies: Some recent advances. Antibody, Immunoconjugates and Radiopharmaceuticals 1991 4 389–398.
- Morphy, JR Parker, D Kataky, R Harrison, A Eaton, MAW Millican, A Phipps, A Walker, C Towards tumour targeting with copper radiolabelled macrocycle-antibody conjugates. J. Chem. Soc. Chem. Comm. 1989 792–794.
- Meares, CF Studer, M Diril, H Kukis, DL Preparation and characterisation of new bifunctional chelating agents for copper-67. J. Nucl. Med. 1992 33 942.
- Kukis, DL DeNardo, SJ DeNardo, GL Diril, H McCall, MJ Meares, CF Radiolabelling of antibody-macrocycle chelate conjugates. J. Nucl. Med. 1992 33 1031.
- King, DJ Mountain, A Adair, JR Owens, RJ Harvey, A Weir, N Proudfoot, KA Phipps, A Lawson, A Rhind, SK Pedley, B Boden, J Boden, R Begent, RHJ Yarranton, GT Tumour localisation of engineered antibody fragments. Antibody, Immunoconjugates and Radiopharmaceuticals 1992 5 159–170.
- Meredith, RF Khazaeli, MB Plott, WE Brezovich, IA Russell, CD Wheeler, RH Spencer, SA LoBuglio, AF Comparison of two mouse/human chimeric antibodies in patients with metastatic colon cancer. Antibody, Immunoconjugates and Radiopharmaceuticals 1992 5 75–80.
References to Patent Literature
- The Wistar Institute US4172124.
- Goldenberg DM EP-35265-A.
- Hybritech Inc UK2109407.
- Gansow, OA, Strand, M UK2122641.
- Celltech Ltd WO8705030.
- The University of California US4678667.
- Celltech Ltd WO8901475.
- Celltech Ltd WO9009379.
- Celltech Ltd EP-404605-A.
- US Department of Commerce WO8911475.
- US Department of Commerce WO9114458.
- Schering AG EP-255471-A.
- Guerbet SA EP-365412-A.
- Bracco Ind Chim SpA WO8905802.
- ER Squibb & Sons Inc EP-232751-A.
- Nycomed AS WO8900557.
- Celltech Ltd WO8901476.
- Celltech Ltd EP-382582-A.
- Celltech Ltd EP-457438-A.
- The Dow Chemical Company US4882142.
- Celltech Ltd EP-455380-A.