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Cardiovascular Agents (Including Blood Products)

Patent Evaluation: Phenoxyalkanoic Acids as Cholesterol Lowering Agents

Pages 1921-1923 | Published online: 02 Mar 2011

Key References

  • Thorp, JM Waring, WS Modification of metabolism and distribution of lipids by ethyl chlorophenoxyisobutyrate. Nature 1962 194 948–949.
  • Kritchevsky, D Sallata, P Tepper, SA Influence of ethyl p-chlorophenoxyisobutyrate (CPIB) upon establishment and progression of experimental atherosclerosis in rabbits. J. Atheroscler. Res. 1968 8 755–761.
  • Hellman, L Zumoff, B Kessler, G Kara, E Rubin, IL Rosenfeld, RS Reduction of cholesterol and lipids in man by ethyl p-chlorophenoxyisobutyrate. Ann. Intern. 1963 59 477–494.
  • Oliver, MF Further observations on the effect of atromid and ethyl cholorphenoxyisobu-tyrate on serum lipid levels. J. Lipid Res. 1963 3 427–444.
  • Hinninghake, DB Tucker, DR Azarnoff, DL Long term effects of clofibrate (Atromid-5) on serum lipids in man. Circulation 1969 39 675–683.
  • Witiak, DT Newman, HAI Feller, DR Clofibrate and related analogs. A comprehensive review. Marcel Dekker New York1977.

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