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Anti-Inflammatory, Anti-Allergic, Respiratory & GI Agents

Overview: Recent Advances in Elastase Inhibitors

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Pages 573-581 | Published online: 02 Mar 2011

Reference to Primary Literature

  • Robert L, Hornebeck W Elastin and Elastases CRC-Press Boca Raton, Fla. 1989 I-II Vol. II is devoted to elastases and inhibitors.
  • Balo J, Babga I Elastase and elastase inhibitor. Nature 1949 164 491.
  • Balo J Connective tissue changes in atherosclerosis. ‘International Review of Connective Tissue Research’ Hall DA Academic Press New York 1963 I 241–306.
  • De Cremoux H, Hornebeck W, Jaurand MC, Bignon J, Robert L Partial characterization of an elastase-like enzyme secreted by human and monkey alveolar macrophages. J. Pathol. 1978 125 172–177.
  • Lafuma C, Hornebeck W Macrophage elastase. ‘Elastin and Elastases’ Robert L Hornebeck W Boca Raton, Fla 1989 II 39–48.
  • Szendroi M, Meimon G, Bakala H, Frances C, Robert L, Godeau G, Hornebeck W On the presence of a metalloprotease in human skin fibroblasts that degrades the human skin elastic fibre system. J. Invest. Dermatol. 1984 83 224–229.
  • Pelletier-Lebon P, Homsy R, Godeau G, Robert L, Hornebeck W An elastin degrading endopeptidase (EC 3.4.24) from human skin fibroblasts. Cutaneous developments, Aging and Repair Abatangelo G. Davidson JM Fidia Research Series Liviana Press, Padova 1989 18 341–345.
  • Robert B, Derouette JC, Robert L Mise en évidence d'une protéase à activité élastolytique dans les extraits d'aortes humaines et animales. C.R. Acad. Sci. (Paris) 1974, 3251–3254.
  • Hornebeck W, Robert L Aortic elastase. ‘Elastin and Elastases’ Robert L Hornebeck W Boca Raton, Fla. 1989 II 49–56.
  • Robert L, Samuel P Mechanism of elastolysis by pancreatic elastase. Experientia 1957 13 167–170.
  • Robert B, Hornebeck W, Robert L Cinétique hétérogéne de l'interaction élastine-élastase. Biochimie 1974 56 239–244.
  • Robert B, Robert L Studies on the structure of elastin and the mechanism of action of elastolytic enzymes. ‘Chemistry and Molecular Biology of the Intercellular matrix’ Balazs EA Academic Press New York 1970 1 665–670.
  • Hornebeck W, Bellon G, Brechemier D, Godeau G, Robert L Control of elastic tissue destruction by elastase inhibitors. ‘Connective Tissue Research: Chemistry, Biology and Physiology’ Deyl Adam Alan R. Liss Inc. New York 1981, 233–246.
  • Bieth J Elastases: Structure, function and pathological role. ‘Frontiers of Matrix Biology’ Robert L. S. Karger Basel 1978 6 1–82.
  • Robert L, Bellon G, Hornebeck W Characterization of different elastases. Their possible role in the genesis of emphysema. Bull. Europ. Physiopath. Resp. 1980 16 199–206.
  • Robert L, Robert AM Elastin, elastases and arteriosclerosis. ‘Frontiers of Matrix Biology: Biology and Pathology of Elastic Tissues’ Robert AM Robert L S. Karger Basel 1980 8 130–173.
  • Claire M, Jacotot B, Robert L Characterization of lipids associated with macro-molecules of the intercellular matrix of human aorta. Conn. Tis. Res. 1976 4 61–71.
  • Jacob MP, Hornebeck W, Robert L Studies on the interaction of cholesterol with soluble and insoluble elastins. Int. J. Biol. Macromol. 1983 5 275–278.
  • Robert L, Labat-Robert J, Hornebeck W Aging and atherosclerosis. ‘Atherosclerosis Reviews’ Gotto AM Paoletti R Raven Press 1986 14 143–170.
  • Boudier C, Godeau G, Hornebeck W, Robert L, Bieth JG The elastolytic activity of cathepsin G: An ex vivo study with dermal elastin. Am. J. Respir. Cell. Mol. Biol. 1991 4 497–503.
  • Robert L Mécanismes cellulaires et moléculaires du vieillissement Masson Paris 1983.
  • Crystal RG The biochemical basis of pulmonary function Marcel Dekker, Inc. 1976.
  • Tixier JM, Godeau G, Robert AM, Hornebeck W Evidence by in vivo and in vitro studies that binding of pycnogenols to elastin affects its rate of degradation by elastases. Biochem. Pharmacol. 1984 33 3933–3939.
  • Robert AM, Robert L Gefässwandabdichtung durch Makromoleküle. Klinik Journal 1984 9 32–33.
  • Barrett AJ, Salvesen G Proteinase inhibitors Elsevier Amsterdam 1986.
  • Zimmermann M, Powers JC Design and properties of synthetic elastase inhibitors. ‘Elastin and Elastases’ Robert L Hornebeck W Boca Raton, Fla. 1989 II 109–123.
  • Redini F, Tixier JM, Petitou M, Choay J, Robert L, Hornebeck W Inhibition of leucocyte elastase by heparin and its derivatives. Biochem. J. 1988 252 515–519.
  • Finch CE, Hayflick L Handbook of the Biology of Aging Van Nostrand Rein-hold Co. 1977.
  • Hornebeck W, Moczar E, Szecsi J, Robert L Fatty acid peptide derivatives as model compounds to correct elastin against degradation by elastases. Biochem. Pharmacol. 1985 34 3315–3321.
  • Godeau G, Gonnord G, Jolivet O, Schoevaert D, Pompidou A, Lagrue G, Robert AM A selective histochemical method for the quantitative estimation of elastic fibres by computerized morphometric analysis. Effect of colchicin treatment. Anal. Quant. Cytol. Histol. 1986 8 321–325.
  • Godeau G, Robert AM Use of pycnogenols in the histological staining of elastic fibres and their quantification in several tissues by automated image analysis. ‘Elastin and Elastases’ Robert L Hornebeck W CRC Press Boca Raton 1989 I 7–19.
  • Fulop T, Wei SM, Robert L, Jacob MP Determination of elastin peptides in normal and arteriosclerotic human sera by ELISA. Clin. Physiol. Biochem. 1990 8 273–282.
  • Wei SM Etudes immunologiques des peptides d'élastine et leurs applications Thése Doctorat Univ. Paris-XII 1992.
  • Harf A, Lafuma C, Kemeny A, Robert AM Effects of keracyanin on elastase induced emphysema in hamsters. Fed. Proc. 1984 43 527.
  • Robert L, Godeau G, Gavignet-Jeannin, Groult N, Six C, Robert AM Action des oligoméres procyanidoliques sur la perméabilité de la paroi vasculaire. Etude par morphologie quantitative. Path. Biol. 1990 38 608–616.
  • Robert AM, Groult N, Six C, Robert L Etude de l'action des oligomeres pro-cyanidoliques sur des cellules mésenchymateuses en culture. II. L'attachement des fibres élastiques aux cellules. Path. Biol. 1990 38 601–607.
  • Jacob MP, Fülöp T Jr, Foris G, Robert L Effect of elastin peptides on ion fluxes in mononuclear cells, fibroblasts and smooth muscle cells. Proc. Natl. Acad. Sci. 1987 84 995–999.
  • Varga Z, Jacob MP, Robert L, Fülöp T Jr Identification and signal transduction mechanism of elastin peptide receptor in human leukocytes. FEBS Letters 1989 258 5–8.
  • Robert L, Jacob MP, Fülöp T Jr, Timar J, Hornebeck W Elastonectin and the elastin receptor. Pathol. Biol. 1989 37 736–741.
  • Fülöp T, Jacob MP, Foris G, Varga Z Effects of elastin peptides on ion fluxes. ‘Cell Calcium Metabolism’ Fiskum Gary Plenum Publishing Corporation 1989, 617–622.

References to Patent Literature

Reference to Patent Literature

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