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Cardiovascular Agents (Including Blood Products)

Patent Evaluation: Novel Tetralones as Potassium Channel Activators

Pages 1471-1472 | Published online: 02 Mar 2011

Key References

  • Kajioka, S Nakashima, M Kitamura, K Kuriyama, H Mechanisms of vasodilation induced by potassium channel activators. Clin. Sci. 1991 81 129–139.
  • Edwards, G Weston, AH Structure-activity relationships of K+ channel openers. Trends Pharmacol. Sci. 1990 11 417–422.
  • Donnelly, R Elliott, HL Meredith, PA Reid, JL Clinical studies with the potassium channel activator conahalin in normotensive and hypertensive subjects. J. Cardiovasc. Pharmacol. 1990 16 790–795.
  • Goldberg, MR Clinical pharmacology of pinacidil, a prototype for drugs affecting potassium channels. J. Cardiovasc. Pharmacol. 1988 12 Suppl 2 541–549.

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