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Original Article

Patent Evaluation: Tetronic acid derivatives as PLA2 inhibitors

Pages 58-59 | Published online: 03 Mar 2008

References

  • GLASER KB, LOCK YW, CHANG JY: PAF and LTII4 biosynthesis in the human neutrophil: Effects of putative inhibitors of phospholipase A2 and specific inhibitors of 5-lipoxygenase. Agents and Actions (1991) 34:89.
  • GARST ME: Phospholipase A2 Inhibitors. Curr. Opin. Thera. Patents (1992) 2:400.
  • DEVRTES OW, LEE G, AMDAHL L, WENZEL M, HARCOURT D, HOLMES J, SYAGE E, GARST M, WHEELER L: Manoalide. Drugs of the Future (1990) 15:460.
  • KREFT A, NELSON J, MUSSER .1 et al.: Structure-activity relationships leading to WAY-121,520, a tris-aryl indomethacin-based PLA2 inhibitor. 203rd ACS Meeting Abstract (1992) Medchm 144.

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