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Original Article

Patent Evaluation: The use of NMDA antagonists for the treatment of alcohol withdrawal symptoms

Pages 313-314 | Published online: 03 Mar 2008

Key References

  • WONG EHF, KEA4P JA, PRIESTLEY T et al.: The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc. Natl. Acad. ScL USA (1986) 83:7104–7108.
  • ROGAWSKI MA et al.: Epilepsy (1990) 31:620.
  • DINGLEDINE R, McBAIN CJ, MCNAMARA JO: Excitatory amino acid receptors in epilepsy. TIPS (1990) 11:334–338.
  • GRANT KA, VALVERIUS P, HoDsPrni M et al.: Ethanol withdrawal seizures and the NMDA receptor complex. Eur. J. PharmacoL (1990) 176:289–296.
  • VALERROS P, CRABBE JC, HOFFMAN PL et al.: NMDA receptors in mice bred to be prone Or resistant to ethanol withdrawl seizures. Eur. J. PharmacoL (1990) 184:185–189.
  • KHANNA JM, SHAH G, WEINER J et al.: Effect of NMDA receptor antagonists on rapid toler-ance to ethanol. Eur. J. PharmacoL (1993) 230:23–31.

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