6
Views
1
CrossRef citations to date
0
Altmetric
Research

Patent Update Biologicals and Immunologicals: Transgenic animal models and gene therapy

, &
Pages 237-245 | Published online: 03 Mar 2008

References

  • JAENISCH R: Germ line integration and Mengii.linn Transmission of the Exogenous Moloney LeukemiaVirus. Proc. Natl. Acad. Sci. USA (1976) 73:1260–1264.
  • JAENISH R, FAN H, CROICER B: Infection of preimplanta-don mouse embryos and of newborn mice with leuke-mia virus: Tissue distribution of viral DNA and RNA and leukemogenesis in the adult animaL Proc. Natl. Acad. kJ. USA (1975) 72:4008–4012.
  • STEWART CL, STUHLMANN H, JAHNER D, JAENISCH R: Denovo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carci-noma cells. Proc. Natl. Acad. Sci. USA (1975) 72:4008–4012.
  • HODGSON CP, CHAKRABORTY AK, BOMAN BM: Retrovi-ral vectors for gene therapy and transgenics. Curr. Opin Thera. Patents (1993) 3:223–235.
  • GORDON JW, SCANGOS GA, PLOTKIN DJ, BARBOSA JA,RUDDLE FH: Genetic transformation of mouse embryos by microinjection of purified DNA. Proc. Natl. Acad. Sci. USA (1981) 78:7380–7384.
  • WAGNER EF, S1EWART TA, MINTZ B: The human13-globin gene and a functional viral thymidine kinase gene indeveloping mice. Proc. Natl. Acad. Sci. USA (1981) 78: 5016–5020.
  • WAGNER TE, HOPPE PC, JOLLICK JD, SCHOU DR HODINKA EL, GAULT JB: Microinjection of a rabbit 13-globin gene into zygotes and its subsequent expres-sion in adult mice and their offspring. Proc. Natl. Acad. Sci. USA (1981) 78:6376–6380.
  • COSTANTINI F, LACY E: Introduction of a rabbit 0-globin gene into the mouse germ line. Nature (1981) 294:92–94.
  • BRINSTER EL, CHEN HY, TRUMBAUER M, SENEAR AW, WARREN R, PALMITER RD: Somatic expression of herpes thytnidine ldnase in mice following injection of a fusion gene into eggs. Cell (1981) 27:223–231.
  • PALMITER RD, BRINSTER EL, HAMMER RE, TRAMBAUER ME, ROSENFELD MG, BRINGER NC, EVANS EM: Dramaticgrowth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature (1982) 300:611–615.
  • GOSLER A, DOETSCHMAN J, KORN R et al.: Transgenic by means of blastocyst-derived embryonic stem cell lines.Proc. Natl. Acad. Sci. USA (1986) 83:9065–9069.
  • HOGAN B, CONSTANTINI F, LACY E: Manipulating the Mouse Embryo: A Laboratory Manual. (1986) Cold Spring Harbor Laboratory, New York.
  • COLLIS P, ANTONIOU M, GROSVELD F: Definition of the Minimal Requirements within the Human Beta-Globin Gene and the Dominant Control Region for High Level Expression. EMBO J. (1990) 9:233–240.
  • STRAUSS WM, DAUSMAN J, BEARD C et al.: Germ Line Transmission of a Yeast Artificial Chromosome Span-ning the Murine alpha 1(I) collagen locus. Science (1993) 259: 1904-1907.
  • PENNISI E: A Mouse of a different YAC. Science News143:360–363.
  • CAPECCHI MR: Altering the genome by homologous recombination. Science (1989) 244:1288–1292.
  • KIM H-S, POPOVICH BW, SHEEHEE WR et al.: Problems encourtered in detecting a targeted gene by the polym-eras e chain reaction. Gene 103:227–233.
  • WOOD SA, ALLEN ND, ROSSANT J, ALTERBACK A, NAGYA: Non- injection methods for the production of embry-onic stem cell- embryo chimaeras. Nature (1993) 365:87–89.
  • HUGHES SH, GREENHOUSE JJ, PETROPOULOS CJ, SU-TRAVE P: Adaptor plasmicis the insertion of foreign DNA Into helper-independent retroviral vectors. J. Virol. (1987) 61:3004–3012.
  • S, TEMIN H: Construction of a helper cell line for avianretroculoendotheliosis virus cloning vectors. Mol. Cell Biol. (1983) 3:2241–2249.
  • SALTER DW, CRITTENDEN LB: Artificial insertion of a dominant gene for resistance to avian leukosis virus Into the germ line of the chicken. Timor. Appl. Genet. 77:457461.
  • BOSSELMAN RA, HSU R-Y, BOGGS T et al.: Germlinetransmission of exogenous genes in the chicken. Sci-ence (1989) 243:533–535.
  • COOK RE, COOK SJ, SAVON S, MCGRANE M, HARTITZ M,HANSON RW, HODGSON CP: Liver-specific expression of a phosphoenolpyruvate carboxykinase-neo gene in genetically modified chickens. Poultry Sci. (1993) 72:554–567.
  • NORTON JD, HOGAN BL: Temporal and tissue specific expression of distinct retrovirus-like (VL30) elements during mouse development. Dev. Biol. (1988) 125:226–228.
  • CHA1CRABORTY AK, ZINK MA, CHUN MA, HODGSON CP: Synthetic retrotransposon VL30 vectors for gene ther-apy, transgenics, and research. In: Miami Short Reports (1994). Vol 4 (in press).
  • COSGROVE DE, CHAKRABORTY AK, GRUNKEMEYER JA, HODGSON CP: VL30 vectoring systems: some surprises in their regulation in embryonic stem cells. J. Cell. Biochem. (1993) Suppl 17E:235.
  • CHAICRABORTY AK, ZINK MA, BOMAN BM, HODGSON CP: Synthetic retrotransposon vectors for gene therapy. FASEB J. (1993) 7:971–977.
  • COSGROVE D, GRAY D, DIERICH A et al.: Mice lacking MHC class ll molecules. Cell (1991) 66:1051–1066.
  • CHAN SH, COSGROVE D, WALTZINGER C et al.: Another view of the selective model of thymocyte selectin. Cell (1993) 73:225–236.
  • SHINKAI Y, RATHBLTN G, LAM K-P et al.: RAG-2-deficient mice lack mature lymphocytes owing to inability to Initiate V(D)J rearrangement. Cell (1992) 68:855–867.
  • WEISSENBACH J, GYAPAY G, DIB C et al.: A second generation linkage map of the human genome. Nature (1993) 359:1083–1088.
  • SNOUWAERT J et al.: An animal model for cystic fibrosis made by gene targeting. Science (1992) 247:1083–1088.
  • GABRIEL SE, CLARK RE, BOUCHER RC et al.: CFTR and outward rectifying chloride channels are distinct pro-teins with a regulatory relationship. Nature (1993) 363:263–268.
  • DAVIGNON J, GREGG RE, SING CF: Apolipoprotein E polymorphism and atherosclerosis. Atherosclerosis (1988) 8:1–21.
  • PLUMP AS, SMITH JD, HAYEK T et al.: Sever hyper-cholesterolernia and and atherosclerosis in apolipo-protein E-deficient mice created by homologous recombination in ES cells. Cell (1992) 71:343–353.
  • CARDIFF RD, LEDER A, KUO A et al.: Multiple tumour types appear in a transgenic mouse with the ras onco-gene. Am.J. Patbol. (1993) 142:1199–1207.
  • MURAKAMI H, SANDERSON ND, NAGY P et al.: Transgenic mouse model for the synergistic effects of nuclear oncogenes and growth factors in tumourigenesis: in-teraction of c-myc and transgorming growth factor alpha in hepatic oncogenesis. CancerRes. (1993) 53:1719–1723.
  • HAMMER RE, PURSEL VG, REXROAD CE, WALL RJ, BOLT DJ, EBERT KM, RALMITER RD, BRINSTER RE: Production of transgenic rabbits, sheep and pigs by microinjection. Nature (1985) 315:680–683.
  • PURSEL VG, HAMMER RE, BOLT DJ, PALMITER RD, MUN-STER RL: Integration, expression and germ-line trans-mission of growth-related genes in pigs. J. Reprod. Fert. (1990) Suppl. 41:119–124.
  • WIEGHART M, HOOVER JL, MCGRANE MM, HANSON RW, ROTTMAN FM, HOLZMAN SH, WAGNER YE, PINICERT CA: Production of transgenic pigs harbouring a rat phos-phoenolpyruvate carboxykinase-bovine growth hor-mone fusion gene. J. Rep rod. Fert. (1990) 41:89–96.
  • REXROAD CE, HAMMER RE, BEHRINGER RR, PALMITER RD, BRINSTER EL: Insertion, expression and physiology of growth- regulating genes in ruminants. J. 1?eprod. Fert. (1990) Suppl. 41:119–124.
  • JANNE J, HYTTINEN J-M, PEURA R, TOLVANEN M, AL-HONEN L, HALMEKYTO M: Transgenic animals as bin-producers of therapeutic proteins. Ann. Med. (1992) 24:273–280.
  • BRINSTER EL, ALLEN JM, BEHRINGER RR, GELINAS RE, PALMITER RD: Introns increase transcriptional effi-ciency in transgenic mice. Proc . Natl. Acad. Sci. USA (1988) 85:836–840.
  • WRIGHT G, CARVER A, COTTOM D, REEVES D, SCOTT A,SIMONS P, WILMUT I, GARNER I, COLMAN A: High level of expression of active human alpha-l-antitrypsin in the milk of transgenic sheep. Bio/Tecbnology (1991) 9:830–834.
  • SHARMA A, MARTIN MJ, O'ABE JF, TRUGLIO RA, DHANJALNK, LOGAN JS, KUMAN R: An isologous procine pro-moter permits high level expression of human hemo-globin in transgenic swine. Bio/Technology (1994) 12:55–59.
  • TOWELL J: Transgenic animal experiments. Bio/Technol-ogy (1993) 11:966.
  • MULLER M, BRENIG B, WINNACICER E-L, BREM G: Trans-genic pigs carrying cDNA copies encoding the murine Mx1 protein which confers resistance to influenza virus Infection. Gene (1992) 121:263–270.
  • SALTER DW, CRITTENDEN LB: Artificial insertion of adominant gene for resistance to avian leukosis virus into the germ line of the chicken. Timor. AppL Genet. (1989) 77:457461.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.