References
- MATTHEWS REF: Classification and nomenclature of viruses. 4th Report of the International Committee on Taxonomy of Viruses. InWrvirol. (1982) 17: 52–54.
- The biology of baculoviruses. Volume 1. Biological prop-erties and molecular biology (1986). GRANADOS RR, FED-ERICI BA (Eds.), CRC Press, Inc Boca Raton, Florida.
- BLISSARD GW, ROHRMANN GF: Baculovirus diversityand molecular biology. Ann. Rev. Entomol. (1990) 35: 127–155.
- VOLKMAN LE, GOLDSMITH PA, HESS RT, FAULKNER P: Neutralisation of budded Autograpba californica NPV by a monoclonal antibody: identification of the target antigen. Vim!. (1984) 133: 354–362,
- VOLKMAN LE: The 64k envelope protein of budded Autograpba californica NPV. Curr. Top. Microb. Immu-nol. (1986) 131: 103–118.
- HARRAP KA: The structure of nuclear polyhedrosis viruses. I The inclusion body. Virol. (1972) 50: 114–123.
- KEDDIE BA, VOLKMAN LE: Infectivity difference be-tween the two phenotypes of Autograpba californica nuclear polyhedrosis virus: importance of the 64K envelope glycoprotein. j Gee. Virol. (1985) 66: 1195–2000.
- VOLKMAN LE, GOLDSMITH PE: Mechanism of neutrali-sation of budded Autograpbica californica nuclear polyhedrosis virus by a monoclonal antibody: inhibi-tion of entry by adsorptive endocytosis. Virol. (1985) 143: 185–195.
- BLISSARD GW, WENZ JR: Baculovirus gp64 envelope glycoprotein is sufficient to mediate pH dependent membrane fusion.1 Virol. (1992) 66: 6829–6835.
- KEDDIE BA, APOINTE GW, VOLKMAN LE: The pathway of infection ofAutograpba californica nuclear polyhe-drosis virus in an insect host Science (1989) 242: 1728–1730.
- KUZIO J, JAQUES R, FAULKNER P: Identification of p74,a gene essential for virulence of baculovirus occlusion bodies. Ora (1989) 242: 759–763.
- FAULKNER P, anuums GV, KUZIO J: A viral structural gene affecting the virulence of baculovirus occlusion bodies. In: Proceedings of the baculovirus and recombinant protein production workshop. Interlaken, Switzerland (1992). Viak JM, Schlaeger E-J, Bernard AR (Eds.) Editions Roches, Basel, Switzerland.
- VOLKMAN LE, KEDDIE BA: Nuclear polyhedrosis virus pathogenesis. Seminars in Vim!. (1990) 1: 249–256.
- KELLY DC, LESCOTT T: Baculovirus replication: protein synthesis inSpodoptera frugiperda cells infected with Trtcboplusia nf nuclear polyhedrosis virus. Microbiol. (1981) 4: 350–357.
- LLTBBERT H, DOERFLER W: Transcription of overlapping sets of RNAs from the genome of Asdograpba califor-nica nuclear polyhedrosis virus: a novel method for mapping RNAs.J, Virol. (1984) 52: 255–265.
- FRIESEN PD, MILLER LK: Temporal regulation of baculovirus RNA: overlapping early and late transcripts. J. Virol. (1985) 54: 392–400.
- FRIESEN PD, MJII.FR LK: The regulation of baculovirus gene expression. Curr. Top. Microbiol. Immunol. (1986) 131: 31–49.
- MAINPRIZE TH, LEE K, MILLER LK: Variation in the tem-poral expression of overlapping baculovirus tran-scripts. Virus Res. (1986/87) 6: 85–99.
- FRIESEN PD, MIILER LK: Divergent transcription of early 35- and 94-kilodalton genes encoded by the HindM K genome fragment of the baculovirus Autograpba cali-fornica nuclear polyhedrosis virus. J. Virol. (1987) 61: 2264–2272.
- GUARINO LA, SUMMERS MD: Functional mapping of a trans -activating gene required for expression of a bacu-lovirus delayed-early gene. J. Virol. (1986) 57: 563–571.
- CARSON DD, GUARINO LA, SUMMERS MD: Functional mapping of an AcNPV Immediate early gene which augments expression of the TE-1 trans-activated 39K gene. Virol. (1988) 162: 444–451.
- CHISHOLM GE, HENNER DJ: Multiple early transcripts and splicing of the Autograpba californica nuclear polyhedrosis virus 1E-1 gene. J. Vim!. (1988) 62: 3198–3200.
- First report of splicing of baculovirus transcripts.
- ICRAPPA R, KNEBEL-MORSDORF D: Identification of the very early transcribed baculovirus gene PE-38. J. Vim!. (1991) 65: 805–812.
- KNEBEL-MORSDORF D, KREMER A, JAHNEL F: Baculovirus gene ME53, which contains a putative zinc finger motif, Is one of the major early-transcribed genes. J. Vim!. (1993) 67: 753–758.
- GUARINO LA, SUMMERS MD: Nucleotide sequence and temporal expression of a baculovirus regulatory gene. J. Vim!. (1987) 61: 2091–2099.
- CARSON DD, SUMMERS MD, GUARINO LA: Transient expression of theAutograpba californica nudear poly-hedrosis virus immediate-early gene, 1E-N, is regulated lby three viral elements. J. Virol. (1991) 65: 945–951.
- KOVACS GR, GUARINO LA, SUMMERS MD: Novel regula-tory properties of the 1E1 and EEO transactivators en-coded by the baculovirus Autograpba californica muhicapsid nuclear polyhedrosis virus. J. Vim!. (1991) 65: 5281–5288.
- FUCHS LY, WOODS MS, WEAVER FR: Viral transcriptionduring Autograpba californica nuclear polyhedrosis virus infection: a novel RNA polymerase induced in infectedSpodopterafrugiperda cells. J. Vim!. (1983) 48: 641–646.
- HUH NE, WEAVER RE: Identifying the RNA polymerasesthat synthesize specific transcripts of the Autograpba californica nuclear polyhedrosis virus. J. Gen. Viro/. (1990) 71: 195–201.
- YANG CL, STETLER DA, WEAVER RE: Structural compari-son of the Autograpba californica nuclear polyhe-drosis virus-induced RNA polymerase and the three nuclear polymerases from the host, Spodoptera frugiperda. Virus Res. (1991) 20: 251–264.
- GLOCKER B, HOOPES JR. RR, ROHRMANN GF: In vitro transactivation of baculovirus early genes by nuclear extracts from Autograpba californica nuclear polyhe-drosis virus-infected Spodoptera frugiperda cells. J. Vim!. (1992) 66: 3476–3484.
- MILLER LK, JEWELL JE, BROWNED: Baculovirus induction of a DNA polymerase. J. Vim!. (1981) 40: 305–308.
- WANG X, KELLY DC: Baculovirus replication: purifica-tion and identification of the Tricboplusia xi nuclear polyhedrosis virus-induced DNA polymerase. J. Gen. Vim!. (1983) 64: 2229–2236.
- TOMALSKI MD, WU J, MILLER LK: The location, sequence, transcription and regulation in the baculovirus DNA polymerase gene. Vim!. (1988) 167: 591–600.
- LU A, CARSTENS EB: Nucleotide sequence of a gene essential for viral DNA replication in the baculovirus Autograpba californica nuclear polyhedrosis virus. Virology. (1991) 181: 336–347.
- GUARINO LA, SUMMERS MD: Functional mapping of Autograpba californica nuclear polyhedrosis virus genes required for late gene expression. J. Vim!. (1988) 62: 463–471.
- COCHRAN MA, CARSTENS EB, EATON BT, FAULKNER P:Molecular cloning and physical mapping of restriction endonuclease fragments of Autograpba californica nuclear polyhedrosis virus DNA. J. Virol. (1982) 41: 940–946.
- Baculovirus expression vectors. In: A laboratory manual. (1992). O'REILLY DR, MILLER LK, LUCKOW VA (Eds.), WH Freeman and Company, New York.
- TJIA ST, CARSTENS EB, DOERFLER W: Infection of Spo-doptera frugipercla cells withAutograpba californica nudear polyhedrosis virus. IL The viral DNA and the kinetics of its replication. Vitro!. (1979) 99: 399–409.
- GORDON JD, CARSTENS EB: Phenotypic characterisation and mapping of a temperature sensitive mutant of Autograpba callfornica nuclear polyhedrosis virus de-fective in DNA synthesis. Virol. (1984) 138: 69–81.
- MARUNIAK JE, SUMMERS MD, FALCON LA, SMITH GE:Autograpba californica nuclear polyhedrosis virus structural proteins compared from in vivo and in vitro sources. Intennrol. (1979) 11: 82–88.
- STILES B, WOOD HA: A study of the glycoproteins ofAutograpba californica nuclear polyhedrosis virus (AcNPV). Virol. (1983) 131: 230–241.
- THIEM SM, MILLER LK: Identification, sequence, and transactional mapping of the major capsid protein gene of the baculovirus Autograpba califorwica nuclear polyhedrosis virus. J. Vim!. (1989) 63: 2208–2018.
- WHITFORD M, FAULKNER P: Nucleotide sequence andtranscriptional analysis of a gene encoding gp41, a structural glycoprotein of the baculovirus Autograpba californica nuclear polyhedrosis virus. J. Vim!. (1992) 66: 4763–4768.
- BLISSARD GW, ROHRMANN GF: Location, sequence, transcriptional mapping and temporal expression of the gp64 envelope glycoprotein of the Orgyia pseudot-sugata multicapsid nuclear polyhedrosis virus. Virol. (1989) 170: 547–555.
- BLISSARD GW, ROHRMANN GF: Baculovirus gp64 geneexpression: analysis of sequences modulating early transcription and transactivation by 1E1. J. Vim!. (1991) 65: 5820–5827.
- ROHRMANN GF: Polyhedrin structure. J. Gen. Virol.(1986) 76: 1499–1530.
- QUANT-RUSSEL RL, PEARSON MN, ROHRMANN GF, BEAUDREAU GS: Characterisation of baculovirus p10 synthesis using monoclonal antibodies. Vim. (1987) 160: 9–19.
- ROHRMANN GF: Baculovirus structural proteins. J. Gen. Vim!. (1992) 73: 749–761.
- VAN DER VILIC F, VAN LENT JWNI, VLAK JM: Immunogolddetection of polyhedrin, p10 and virion antigens in Autograpba californica nudear polyhedrosis virus-in-fectedSpodoptera frugiperda cells. J. Gen. Vim!. (1987) 68: 2614–2623.
- VLAK JM, KLINKENBURG FA, ZAAL KJM, USMANY M, KLINGE-ROODE EC, GEERVLIET JBF, ROOSIEN J, VAN LENT JWM: Function studies on the p10 gene of Autograpba californica nuclear polyhedris virus using a recombinant expressing a p10-13-galactosidase fusion gene. J Gen. Vim!. (1988) 69: 765–776.
- WILLIAMS GV, ROHEL DZ, KUZIO J, FAULKNER P: A cytopathological investigation of Autograpba califor-nica nuclear polyhedrosis virus p10 gene function using insertion/deletion mutants. J. Gen. Virol . (1989)70: 187–202.
- SMITH GE, FRASER MJ, SUMMERS MD: Molecular engi-neering of theAutographa californica nuclear polyhe-drosis virus genomc Deletion mutants within the polyhedrin gene. J. Virol. (1983) 46: 584–594.
- Determination that the polyhedrin protein is dispensable for virus replication in cell culture.
- MIT I.FR IX, LINGG AJ, BULLA JR. IA: Bacterial, viral and fungal insecticides. Science. (1983) 219: 715–721
- LUCKOW VA, SUMMERS MD: Trends in the development of baculovirus expression vectors. Bio/Technol. (1988) 6: 47–55.
- MILLER LK: Baculoviruses as gene expression vectors.Annu. Rev. Micro biol. (1988) 42: 177–199.
- MAEDA S: Expression of foreign genes in insects usingrecombinant baculovirus vectors. Ann. Rev. Entomol. (1989) 34: 351–372.
- WEBB NR, SUMMERS MD: Expression of proteins usingrecombinant baculoviruses. Technique. (1990) 2: 173–188.
- LUCKOW VA: Cloning and expression of heterologousgenes in insect cells with baculovirus vectors. In: Recom-binant DNA technology and application. (1991). PROKOP A, BAJPAI RK, HO CS (Eds.), McGraw-Hill, Inc, New York. 97–152.
- BISHOP DHL: Baculovirus expression vectors. Seminarsin Virol. (1992) 3: 253–264.
- OKER-BLOM C, PETTERSSON RF, SUMMERS MD: Bacu-lovirus polyhedrin promoter-directed expression of rubella virus envelope glycoproteins, El and E2, in Spottoptera frugiperda cells. Virol (1989) 172: 82–91.
- KURODA K, GEYER H, GEYER R, DOERFLER W, ICLENKH-D: The oligosaccharides of influenza virus hemagglu-tinin expressed in insect cells by a baculovirus vector. Virol (1990) 174: 418–429.
- HOSS A, MOAREFI I, SCHEIDTMANN K-H, CISEK LJ, COR-DEN JL, DORNREITER I, ARTHUR AK, FANNING E: Altered phosphorylation pattern of simian virus 40 T antigen expressed in insect cells by using a baculovirus vector. J. Virol (1990) 64: 4799–4807.
- MATSUURA Y, HARADA S, SUZUKI R, WATANABE Y, INQUE Y, SAITO I, MIYAMARA T: Expression of proc-essed envelope protein of hepatitis C virus in mammal-ian and insect cells. J. Virol. (1992) 66: 1425–1431.
- JOHNSON R, MEIDINGER RG, IATROU K: A cellular pro-moter-based expression cassette for generating recom-binant baculoviruses directing rapid expression of passenger genes in infected insects. Virol. (1992) 190: 815–823.
- WESTWOOD JA, JONES IM, BISHOP DHL: Analyses of alternative poly (A) signals for use in baculovirus ex-pression vectors. Virol. (1993) 195: 90–99.
- BISHOP DHL, HILL-PERKINS M, JONES IJ, KITTS PA, LOPEZ-FERBER M, CLARICE AT, POSSEE RD, PULLER J, WEYER U: In: Construction of baculovirus expression vectors. Proceed-ings of the baculovirus and recombinant protein production workshop, Interlaken, Switzerland. (1992). VLAK JM, SCHLAEGER E-J, BERNARD AR (Eds.), Editiones Roche, Basel, Switzerland.
- MANN SG, KING IA: Efficient transfection of insect cellswith baculovirus DNA using electroporation. J. Gen. Virol. (1989) 70: 3501–3505.
- PEAKMAN TC, HARRIS RA, GEWERT DR: Highly efficientgeneration of recombinant baculoviruses by enzymati-cally mediated site-specifk its vitro recombination. Nuc. Acids Res. (1992) 30 (3): 495–500.
- KITTS PA, AYRES MD, POSSEE RD: Linearization of baculovirus DNA enhances the recovery of recombinant virus expression vectors. Nuc. Acids Res. (1990) 18: 5667–5672
- Linearisation of the viral genome increases ratio of recombinant to parental virus.
- KITTS PA, POSSEE RD: A method for producing recombinant baculovirus expression vectors at high fre-quency. BioTechniques (1993) 14: 810–817
- Deletion of an essential gene ensures almost 100 % of virus yield is recombinant virus.
- GODEAU F, SAUCIER C, KOURILSKY P: Replication inhibition by nucleoside analogues of a recombinant Autograpba californica muhicapsid nuclear polyhe-drosis virus harbouring the herpes thymidine kinase gene driven by the 1E-1 (0) promoter: anew way to select recombinant baculoviruses. Nuc. Acids Res. (1992) 20: 6239–6246.
- SMITH GE, SUMMERS MD, FRASER MJ: Production of human 13 interferon in insect cells infected with a baculovirus expression vector. Mol. Cell Biol. (1983) 3: 2156–2165.
- First description of baculoviruses as expression vectors.
- MIYAMOTO C, SMITH GE, FARREL-TOWT, CHIZZONITE R, SUMMERS MD, JU G: Production of human c-myc protein in insect cells infected with a baculovirus expression vector. Mol. Cell Biol. (1985) 5: 2860–2865.
- PENNOCK GD, SHOEMAKER C, MILLER IX: Strong and regulated expression of Escbericbia colt fl-galactosi-dase in insect cells with a baculovirus vector. Mol. Cell. Biol. (1984) 4: 399–406.
- LUCKOW VA, SUMMERS MD: Signals important for highlevel expression of foreign genes I Autograpba call-fornica nuclear polyhedrosis virus expression vectors. Virol. (1988) 167: 56–71.
- REIS U, BLUM B, VON SPECHT B-U, DOMDEY H, COLLINSJ: Antibody production in silkworm cells and silkworm larvae infected with a dual recombinant Bombyx mori nuclear polyhedrosis virus. Bio/Technol. (1992) 10: 910–912.
- CARBONELL L, HODGE MR, TOMALSKI MD, MILLER IX:Synthesis of a gene coding for an insect specific scor-pion toxin and attempts to express it using baculovirus vectors. Gene (1988) 73: 409418.
- MATSUURA Y, POSSEE RD, OVERTON HA, BISHOP DHL: Baculovirus expression vectors: the requirements for high level expression of proteins, including glycopro-teins. J. Gen. Virol. (1987) 68: 1233–1250.
- Regions upstream of the polyhedrin initiation codon are essential for optimum activity of the promoter.
- POSSEE RD, HOWARD SC: Analysis of the polyhedrin gene promoter of the Autograpba californica nuclear polyhedrosis virus. Nucl. Acids Res. (1987) 24: 10233–10248.
- RANICIN C, 001 BG, MILLER IX: Eight base-pairs encompassing the transcriptional start point are the major determinant for baculovirus polyhedrin gene expres-sion. Gene (1988) 70: 39–49.
- Determination of the consensus late phase transcriptional start site TAAGTATr.
- 001 BG, RANKIN C, MILLER LK: Downstream sequencesaugment transcription from the essential initiation site of a baculovirus polyhedrin gene. J. Mol. Biol. (1989) 210: 721–736.
- MIN M-K, BISHOP DHL: Transcriptional analyses ofbaculovirus polyhedrin and foreign gene expression relative to baculovirus p10 mRNA levels. J. Gen. Virol. (1991) 72: 2551–2556.
- SMITH GE, JU G, ERICSON BL, MOSCHERA J, LAHM H-W,CHIZZONITE R, SUMMERS MD: Modification and secre-tion of human interleukin 2 produced in insect cells by a baculovirus expression vector. Proc. Natl. Acad. Sci. USA (1985) 82: 8404–8408.
- LUCKOW VA, SUMMERS MD: High level expression ofnonfused foreign genes with Atograpba californica nuclear polyhedrosis virus expression vector. Virol. 170: 31–39.
- PAGE MJ: p36C: an improved baculovirus expressionvector for producing high levels of mature recombinant proteins. Nuc. Acids Res. (1989) 17: 454.
- TESSIER DC, THOMAS DY, KHOURI HE, LALIBERTE F, VERNET T: Enhanced secretion from insect cells of a foreign protein fused to the honeybee melittin signal peptide. Gene (1991) 98: 177–183.
- HASNAIN SE, NAKHAI B: Expression of the gene encod-ing firefly luciferase in insect cells using a baculovirus vector. Gene. (1990) 91: 135–138.
- ICARP M, AICERMAN K, LINDQVIST C, KUUSISTO A, SAVI-RANTA P, OKER-BLOM C: A sensitive model system for in vivo monitoring of baculovirus gene expression in single infected insect cells. Bio/Technol. (1992) 6: 379–386.
- KOPYLOVA-SVRIRIDOVA TN, KRAUZOVA VI, TIMIRYA-SOVA im, CORELOVA TV, SHUPPE NG, FODOR I: Tran-sient expression assay in a baculovirus system using firefly luciferase gene as a reporter. Virus Genes (1992) 6: 379–386.
- DAVIS TR, TROTTER KM, GRANADOS RR, WOOD HA: Baculovirus expression of alkaline phosphatase as a reporter gene for evaluation of production, p,lycosyla-lion and secretion. Bio/Technol. (1992) 10: 1148–1150.
- VLAK JM, SCHOUTEN A, USMANY M, BELSHAM GJ, KLINGE-ROODE EC, MAULE AJ, VAN LENT JWM, ZUIDEMAD: Expression of cauliflower mosaic virus gene 1 using a baculovirus vector based upon the p10 gene and a novel selection method. Virol. (1990) 179: 312–320.
- WEYER U, KNIGHT S, POSSEE RD: Analysis of very late gene expression by Autograpba californica nuclear polyhedrosis virus and the further development of multiple expression vectors. J. Gen. Viral. (1990) 71: 1525–1534.
- Development of dual vectors utilising the two very late hyperactive p10 and polyhedrin promoters.
- HILL-PERKINS MS, POSSEE RD: A baculovirus expression vector derived from the basic protein promoter of Autograpba californica nuclear polyhedrosis virus. J. Gen. Virol. (1990) 71: 971–976.
- THIEM SM, MILLER LK: Differential gene expression mediated by late, very late and hybrid baculovirus promoters. Gene (1990) 9: 87–94.
- TOMALSKI MD, MILI.PR LK: Expression of a paralyticneurotoxin gene to improve insect baculoviruses as insecticides. Bio/TechnoL (1992) 10: 545–549.
- O'REILLY DR, MILLER LK: A baculovirus blocks insectmolting by producing ecdysteroid UDP-glucosyltrans-ferase. Science (1989) 245: 1110–1112.
- O'REILLY DR, MILLER LK: Improvement of a baculoviruspesticide by deletion of the egt gene. Bio/Technol. (1991) 9: 1086–1089.
- ZUIDEMA D, SCHOUTEN A, USMANY M, MAULE AJ, BEL-SHAM GJ, ROOSIEN J, KLINGE-ROODE EC, VAN LENT JWM: Expression of cauliflower mosaic virus gene I in insect cells using a novel polyhedrin based baculovirus ex-pression vector. J. Gen. Virol. (1990) 71: 2201–2209.
- WANG X, 001 BG, MILLER LK: Baculovirus vectors for multiple gene expression and for occluded virus pro-duction. Gene (1991) 100: 131–137.
- ST. ANGELO C, SMITH GE, SUMMERS MD, ICRUG RM: Two of the three influenza viral polymerase proteins ex-pressed using baculovirus vectors form a complex in Insect cells. J. Virol. (1987) 61: 361–365.
- DODSON MS, CRUTE JJ, BRUCKNER RC, LEHMEN lit: Over-expression and assembly of the herpes simplex virus type 1 helicase-primase in insect cells. J. Biol. Chem. (1989) 264: 20835–20838.
- BRAUTIGAM S, SNEZHKOV E, BISHOP DHL: Formation of poliovirus-like particles by recombinant bacukwiruses expressing the individual VPO, VP3 and VP1 proteins by comparison to particles derived from the expressed poliovirus polyprotein. Virol. (1993) 192: 512–524.
- EMERY VC, BISHOP DHL: The development of multiple expression vectors for the high level synthesis of et'. karyotic proteins: expression of LCMV-N and AcNPV polyhedrin protein by a recombinant baculovirus. Prot. Engin. (1987) 1: 359–366.
- TAKEHARA K, IRELAND D, BISHOP DHL: Co-expression of the hepatitis B surface and core antigens using baculovirus expression vectors. J. Gen. Virol. (1988) 69: 2763–2772.
- FRENCH TJ, ROY P: Synthesis of bluetongue virus (HIV) core-like particles expressing the two major structural core proteins of BM. J. Virol. (1990) 64: 1530–1536. Assembly of virus like structures from individual structural proteins expressed within insect cells.
- WEYER U, POSSEE RD: A baculovirus dual expression vector derived from the Autograpba californica nu-clear polyhedrosis virus polyhedrin and p10 promot-ers: co-expression of two influenza virus genes in insect cells. J. Gen. Virol. (1991)72: 2967–2974.
- BELYAEV AS, ROY P: Development of baculovirus triple and quadruple vectors: co-expression of three or fourbluetongue virus proteins and the synthesis of blueton-gm virus-like particles in insect cells. Nuc. Acids Res. (1993) 21: 1219–1223.
- Multiple vectors expressing three and four foreign proteins simulta-neously.
- PATEL G, NASMYTH K, JONES N: A new method for the Isolation of recombinant baculovirus. Nucl. Acids Res. (1992) 20: 79–104.
- LUCKOW VA, UP SC, BARRY GF, OLINS PO: Efficient generation of infectious recombinant baculoviruses by site-specific transposon-mediated insertion of foreign genes into a baculovirus expression genome propagated inEscbericbia coll. J. Virol. (1993) 67: 4566–4579. Generation of virus genome capable of replication in bacterial cells facilitates recombination and selection of viruses.
- KANG CY, BISHOP DHL, SEO J-S, MATSUURA Y, CHLOE M: Secretion of particles of hepatitis B surface antigen from insect cells using a baculovirus vector. J. Gen. Virol. (1987) 68: 2607–2613.
- URUKAWA T, FERGUSON M, MINOR PD,COOPER J, SULLI-VAN M, ALMOND JW, BISHOP DHL: Synthesis of immu-nogenic, but non-infectious poliovirus particles in Insect cells by a baculovirus expression vector. J. Gen. Virol. (1989) 70: 1453–1463.
- FRENCH TJ, MARSHALL JJA, ROY P: Assembly of double-shelled, virus-like particles of bluetongue virus by the simultaneous expression of 4 structural proteins. I Virol. (1990) 64: 1530–1536.
- LOUDON PT, HIRISAWA T, OLDFIELD S, MURPHY M, ROY P: Expression of the outer capsid protein VP5 of two bluetongue viruses, and synthesis of chimeric double-shelled virus-like particles using combinations of re-combinant baculoviruses. Virol. (1991) 182: 793–801.
- GHEYSEN D, JACOBS E, DE FORESTA F, THMIAT C, FRAN-COTTE M, 'MINES D, DE WILDE M: Assembly and release of HIV-1 precursor Pr55 gag virus-like particles from recombinant baculovirus-infected cells. Cell. (1989) 59: 103–112.
- ROYER M, HONG S-S, GAY B, CERUTTI M, BOULANGER P: Expression and extrarelinlar release of human immu-nodeficiency virus type 1 gag precursors by recombi-nant baculovirus-infected cells. J. Virol. (1992) 66: 3230–3235.
- LUO L, LI Y, TUNG CY: Expression of gag precursor protein and secretion of virus-like gag particles of HIV-2 from recombinant baculovirus-infected cells. Virol. (1990) 179: 874–880.
- RASMUSSEN L, BATTLES JK, ENNIS 'CM, NAGASHIMA K, GONDA MA: Characterisation of virus-like partides produced by a recombinant baculovirus containing the gag gene of the bovine immunodeficiency-like virus. Virol. (1990) 178: 435–451.
- SOMMERFELT MA, ROBERTS CR, HUNTER E: Expression of simian type D retroviral (Mason-Pfizer monkey vi-rus) capsids in insect cells using a recombinant bacu-lovirus. Virol. (1993) 192: 298–306.
- ESTES MK, CRAWFORD SE, PENDARANDA ME, PETRIE BL, BURNS JW, CHAN W-K, ERICSON B, SMITH GE, SUMMERS MD: Synthesis and brununogenicity of the rotavirus major capsid antigen using a baculovirus expression system. J. Virol. (1987) 61: 1488–1494.
- SALIKI JT, MIZAK B, FLORE HP, GETTIG RR, BURAND JP, CARMICHAEL LE, WOOD HA, PARRISH CR: Canine parovirus empty capsids produced by expression in a baculovirus vector: use in analysis of viral properties and immunization of dogs. J. Virol. (1992) 73: 369–374.
- REDMAND MJ, IJAZ MK, PARKER MD, SABARA MI, DENT D, GIBBONS E, BABIUK Nig: Assembly of recombinant rotavirus proteins into virus-like particles and assess-ment of vaccine potential. Vaccine (1993) 11: 273–281.
- REID-SANDEN FL, SUMNER JW, SMITH JS, FEKADU M, SHADDOCK JH, BELLINI WJ: Rabies diagnostic reagents prepared from a rabies N gene recombinant expressed In baculovirus. J. Clin. Microbiol. (1990) 28: 858–863.
- SCHMALJOHN CS, SUGIYAMA K, SCHMALJOHN AL, BISHOP DHL: Baculovirus expression of the small genome segment of Hantaan virus and potential use of the expressed nudeocapsid protein as a diagnostic antigen. J. Gen. Virol. (1988) 69: 777–786.
- BARBER GN, CLEGG JCS, LLOYD G: Expression of the Lassa virus nucleocapsid protein in insect cells infected with a recombinant baculovirus: application to diag-nostic assays for Lassa virus infection. J. Gen. Virol. (1990) 71: 19–28.
- SANCHEZ-MARTINEZ D, SCHMID DS, WHITTINGTON W, BROWN D, REEVES WC, CHATTERJEE S, WHITLEY RJ, PELLETT PE: Evaluation of a test based on baculovirus-expressed glycoprotein G for detection of herpes sim-plex virus-type specific antibodies. J. Infect. Dis. (1991) 164: 1196–1199.
- SANCHEZ-MARTINEZ D, PELLETT PE: Expression of HSV-1 and HSV-2 p,lycoprotein G in insect cells by using a novel baculovirus expression vector. Vim. (1991) 182: 229–238.
- BAYLIS SA, PURIFOY DJM, LITTLER E: High-level expression of the Epstein-Barr virus alkaline deoxyribonu-clease using a recombinant baculovirus: application to the diagnosis of nasopharyngeal carcinoma. Virol. (1991) 181: 390–394.
- H1LLE A, KLEIN K, BAUMLER S, GRASSER FA, MUELLER-LANTZSCH N: Expression of the Epstein-Barr virus nu-clear antigen 1,2A and 2B in the baculovirus expression system: serological evaluation of human antibodies to these proteins. J. Med. Virol. (1993)39: 233–241.
- GIUGNI TD, CHURCHILL MA, PANDE H, CAMPO K, GUHA M, ZAIA JA: Expression in insect cells and immune reactivity of a 28K tegument protein of human cy-tomegalovirus. J. Gen. Virol. (1992) 73: 2367–2374.
- HUMMEL KB, ERDMAN DD, HEATH J, BELLINI WJ: Bacu-lovirus expression of the nucleoprotein gene of mea-sles virus and utility of the recombinant protein in diagnostic enzyme immunoassays. J. Ctn. Microbiol. (1992) 30: 2874–2880.
- SALIMANS MMM, VAN BUSSEL MJAWM, BROWN CS, SPAAN WJM: Recombinant parvovirus B19 capids as a new substrate for detection of B19-specific IgG and IgM antibodies by an enzyme linked inummosorbant assay. J. Virol. Meth. (1992) 39: 247–258.
- DUARTE DOS SANTOS CN, KRIEGER MA, ALMEIDA E, LAFAILLE jj, GOLDENBERG S, GALLER R: llypanosoma crux, flagellar repetitive antigen expression by recom-binant baculovirus: towards an improved diagnostic reagent for Chagas' disease. Biorrechnol. (1992) 10: 1474–1477.
- MILLS HR, JONES IM: Expression and purification of p24, the core protein of HIV, using a baculovirus-insect cell expression system. AIDS (1990) 4: 1125–1131.
- GHIASI H, KAIWAR R, NESBURN AB, WECHSLER SL: Ex-pression of herpes simplex virus type 1 glycoprotein B In insect cells. Virus Res. (1991) 22: 25–39.
- GHIASI H, KAIWAR R, NESBURN AB, SLAN-NA S, WECH-SLER SL: Baculovirus-expressed g,lycoprotein E (gE) of herpes simplex virus type-1 (RSV-1) protects mice against lethal intraperitoneal and lethal ocular HSV-1 challenge. Vim. (1992) 188: 469–476.
- GHIASI H, KAIWAR R, NESBURN AB, WECHSLER SL: Ex-pression of herpes simplex virus type 1 glycoprotein I in baculovirus: preliminary biochemical charac-terisation and protection studies. J. Virol (1992) 66: 2505–2509.
- KRISHNA S, BLACKLAWS BA, OVERTON HA, BISHOP DHL, NASH AA: Expression of glycoprotein D of herpes simplex virus type 1 in a recombinant baculovirus: protective responses and T cell recognition of the recombinant-infected cell extracts. J Gen. Vim!. (1989) 70: 1805–1814.
- LANDOLFI V, ZARLEY CD, ABRAMOVITZ AS, FIGUEROA N, WU SL, BLASIAK M, ISHIZAKA ST, MISHKIN EM: Bacu-lovirus-expressed herpes simplex virus type 2 glyco-protein D is immunogenic and protective against lethal HSV challenge. Vaccine (1993) 11: 407–414.
- WELLS DE, VUGLER LG, BRITT WJ: Structural and immu-nological characterization of human cytomegalovirus gp55-116 (gB) expressed in insect cells. J. Gen. Vim!. (1990) 71: 873–880.
- PREHAUD C, TAKEHARA K, FLAMAND A, BISHOP DHL: Immunogenic and protective properties of rabies virus glycoprotein expressed by baculovirus vectors. Vim!. (1989) 173: 390–399.
- FANG FU Z, DIETZSCHOLD B, SCHUMACHER CL, WUNNER WH, ERTL, HCJ, KOPROWSKI H: Rabies virus nucleopro-tein expressed in and purified from insect cells is efficacious as a vaccine. Proc. Natl. Acad. Sci, USA (1991) 88: 2001–2005.
- DFSPRES P, DIETRICH J, GIRARD M, BOULOY M: Recom-binant baculoviruses expressing yellow fever virus E and NS1 proteins elicit protective immunity in mice. J. Gen. Virol. (1991) 72: 2811–2816.
- VAN WYKE COELINGH KL, MURPHY BR, COLLINS PL, LEBACQ-VERHEYDEN A-M, BATTE JF: Expression of bio-logically active and antigenically authentic parainflu-enza type 3 virus haemagglutinin-neuraminidase glycoprotein by a recombinant baculovirus. Virology (1987) 160: 465–472.
- COHEN J: News and comment: lobbying for an AIDS trial. Science (1992) 258: 536–539.
- MicroGeneSys Inc baculovirus-produced HIV gp160 is proposed for vaccine trials, but later blocked.
- HU S-L, ABRAMS K, BARBER GN, MORAN P, ZARLING JM, LANGLOIS AJ, 'CULLER L, MORTON WE, BENVENISTE RE: Protection of macaques against SW infection by subunit vaccines of SW envelope glycoprotein gp160. Science (1992) 255: 456–459.
- SUMMERS MD, ENGLER R, FALCON LA, VAIL P: Bacu-loviruses for insect pest control: safety considerations. Am. Soc. Mic., Washington DC (1975) .
- BURGES HD: In: Microbial control of pests and plant diseases (1981). Academic Press, London.
- MARTIGNONI ME: Baculoviruses: an attractive biological alternative. In: Chemical and biological control in forestry. (1983). GARNER WY, HARVEY J (Eds.), Am. Chem. Soc. Symp. 238: 55–67, American Chemical Society, Easton.
- GRANADOS RR, FEDERICI BA: In: The biology of bacu-loviruses. Volume II. Practical application for insect control (1986). CRC Press, Inc. Boca Raton, Florida.
- HADVTIN RE, KING LA, POSSEE RD: Prospects for the development of a genetically engineered baculovirus insecticide. Pestic. Sci. (1992) 34: 9–15.
- KONDO A, MAEDA S: Host range expansion by recom-bination of the baculoviruses Botnbyx mor/ nuclear polyhedrosis virus and Autograpba californica nu-clear polyhedrosis virus. J. Vim!. (1991) 65: 3625–3632.
- MORI H, NAKAZAWA H, SHIRAI N, SHIBATA N, SUMIDA M, MATSUBARA F: Foreign gene expression by a bacu-lovirus vector with an expanded host range. J. Gen. Vim!. (1992) 73: 1877–1880.
- SUBRAHMANYAM B, RAMAKRISHNAN N: Influence of a baculovirus infection on moulting and food consump-tion by Spodoptera litura. J. Invertbr. Pathol. (1981) 38: 161–168.
- MAEDA S, KAWAI T, OBINATA M, FUJIWARA H, HORIUCHIT, SAEKI Y, SATO Y, FURUSAWA M: Production of human ainterferon in silkworm using a baculovirus vector. Nature (1985) 315: 592–594.
- MIYAJIMA A, SCHREURS J, OTSU K, KONDO A, ARAI K, MAEDA S: Use of the silkworm, Bombyx mori, and an Insect baculovirus for high-level expression and secre-tion of biologically active mouse interleukin-3. Gene (1988) 58: 273–281.
- BISHOP DHL, ENT1WISTLE PF, CAMERON IR, ALLEN CJ, POSSEE RD: Field trials of genetically engineered bacu-lovirus insecticides. In: The release of genetically-engi-neered micro-organisms (1988). SUSSMAN M, COLLINS CH, SKINNER FA, STEWART-TULL DE (Eds.), Academic Press, New York. 143–179.
- BISHOP DHL, POSSEE RD: Planned release of an engi-neered baculovirus insecticide. In: New Directions in Biological Control: Alternatives for suppressing agricultural pests and diseases (1990). BAKER RR, DUNN PE (Eds.), New York, 609–628.
- STEWART LMD, HIRST M, LOPEZ FERBER M, MERRY-WEATHER AT, CAYLEY J, POSSEE RD: Construction of an Improved baculovirus insecticide containing an insect-specific toxin gene. Nature (1991) 352: 85–88.
- Scorpion toxin expressed by polyhedrin-positive baculovirus is efficient as an insecticide in field trials.
- MCCUrCHEN BF, CHOUDARY PV, CRENSHAW R, MAD-DOX D, KAMITA SG, PALEKAR N, VOLRATH 5, FOWLER E, HAMMOCK BD, MAEDA S: Development of a recombi-nant baculovirus expressing an insect-selective neuro-toxin: potential for pest controL Bio/Technol. (1991) 9: 848-851.
- MAEDA S, VOLRATH SL, HANZLIK TN, HARPER SA, MAJIMA K, MADDOCK DW, HAMMOCK BD, FOWLER E: Insectici-dal effects of an insect-specific neurotoxin expressed by a recombinant baculovirus. Virol. (1991)184:777–780.
- TOMALSKI MD, MILLER LK: Insect paralysis by bacu-lovirus-mediated expression of a mite neurotoxin gene. Nature (1991) 352: 82–85.
- TOMALSKI MD, MILLER LK: Expression of a paralytic neurotoxin gene to improve insect baculoviruses as biopesticides. Bio/Technol. (1992) 10: 545–549.
- HOFTE H, WHITELEY HR: Insecticidal proteins of Bacil-lus tburingiensts. Microbiol. Revs. (1989) 53: 242–255.
- LUTHY P, CORDIER JL, FISCHER HM: Bacillus tburingien-sis as a bacterial insecticide: basic consideration and applications. In: Microbial and viral pesticides (1982). KUR-STAK E (Ed.), Marcel Dekker, New York. 35–74.
- MATRENS JWM, HONEE G, ZUIDEMA D, VAN LENT jwm, VISSER B, VLAK JM: Insecticidal activity of a bacterial crystal protein expressed by a recombinant baculovirus In insect cells. Appl. Env. Microbiol. (1990) 56: 2764–2770.
- PANG Y, FRUTOS R, FEDERICI BA: Synthesis and toxicity of full-length and truncated bacterial CtylIVD mosqui-tocidal proteins expressed in lepidopteran cells using a baculovirus vector. J Gen, Virol, (1992) 73: 89–101.
- MAEDA S: Increased insecticidal effect by a recombinant baculovirus carrying a synthetic diuretic hormone gene. Biochem. Biophys. Res. Comm. (1989) 165: 1177–1183.
- HAMMOCK BD, BONNING BC, POSSEE RD, HANZLIK TN, MAEDA S: Expression and effects of the juvenile hor-mone esterase in a baculovirus vector. Nature (1990) 344: 458–461.
- AYRES MD, HOWARD SC, KUZIO J, LOPEZ-FERBER M, POSSEE RD: The complete DNA sequence ofAutograpba californica nuclear polyhedrosis virus. Virology (1994) 202: 580–605.
- Full sequence of the AcNPV genome and putative open reading frame maps
- NERMUT MV, HOCICLEY DJ, jovvErr JBM, JONES IM, GARREAU M, THOMAS D: Pullerene-like organisation of HIV gag-protein by recombinant baculovirus. Virol. (1994) 198: 288–296.
- MOSS SR, NUTTALL PA: Subcore- and core-like particles of Broadhaven virus (BRDV), a tick-borne orbivirus, synthesised from baculovirus expressed VP2 and 'VP7, the major core proteins of BRDV. Virus Res. (1994) 32: 401–407.
- TATMAN JD, PRESTON VG, NICHOLSON P, EnKyrr RM, 06RIXON FJ: Assembly of herpes simplex virus type 1capsids using a panel of recombinant baculoviruses. J Gen. Virol. (1994) 75: 1101–1113.
- The most complex biological structure self-assembled to date, requiring the expression of six separate genes and interactions between seven proteins.
- BROWN CS, WELLING-WEBSTER S, FEIJLBRIEF M, VAN LENT JWM, SPAAN WJM: Chimeric parvovirus B19 cap-sids for the presentation of foreign epitopes. Virol. (1994) 198: 477–488.
- GHIASI H, KAIWAR R, NESBURN AB, SLANINA S, WECH-SLER SL: Expression of seven herpes simplex virus type 1 giycoproteins (gB, gC, gD, gE, gG, gH and gl): com-parative protection against lethal challenge in mice. J. Virol (1994) 68: 2118–2126.
- SISK WE, BRADLEY JD, LEIPOLD 11.J, STOTZFUS AM, PONCE DE LEON M, HILF M, PENG C, COHEN GH, EISENBERG RJ: High-level expression and purification of secreted forms of herpes simplex virus type 1 g,lycoprotein gD synthesized by baculovirus-Infected insect cells.]. Virol. (1994) 68: 766–775.