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Research

Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis Margatoxin: An immunosuppressive scorpion peptide

Pages 827-828 | Published online: 29 Feb 2008

References

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  • BEDNAREK MA, BUGIANESI RM, LEONARD RJ, FELIX JP:Chemical synthesis and structure-function studies of margatoxin, a potent inhibitor of voltage-dependent potassium channel in human T lymphocytes. Biochem. Biopbys. Res. Commun. (1994) 198(2): 619–623.
  • JOHNSON BA, STEVENS SP, WILLIAMSON JM: Determina-tion of the three-dimensional structure of Margotoxin by 111, 13C, 15N triple-resonance nuclear magnetic reso-nance spectroscopy. Biochemistry (1993) 33: 15061–15070.
  • GARCIA-CALVO M, LEONARD RJ, NOVICK J, STEVENS SP,SCHMALHOFER W, KACZOROWSKI GI, GARCIA ML: Puri-fication, characterization, and biosynthesis of marga-toxin, a component of Centruroides nsargaritatus venom that selectively inhibits voltage-dependent po-tassium channels. J. Biol. Chem. (1993) 268(25): 18866–18874.
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