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Miscellaneous

Applications for regulatory region of nitric oxide synthase isoforms

Pages 1525-1528 | Published online: 25 Feb 2005

Bibliography

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  • •One of the very thorough early reviews of NO in biological systems.
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  • •This article, and the following one, are also both quite com-plete compilations of the earlier NO biological literature.
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  • BABU BR, GRIFFITH OW: N5-(1-imino-3-buteny0 4-o-rnithine a neuronal isoform selective mechanism-based inactivator of nitric oxide synthase. J. Biol. Chem. (1998) 273:8882–8889.
  • WEBBER RK, METZ SS, MOORE WM et al.: Substituted 2-iminopiperidines as inhibitors of human nitric oxide synthase isoforms. J. Med. Chem. (1998) 41:96–101.
  • HANSEN DW, JR., PETERSON KB, TRIVEDI M et al.: 2-Iminohomopiperidine salts as selective inhibitors of inducible nitric oxide synthase (iNOS). J. Med. Chem. (1998) 41:1361–1336.
  • SHANKARAN K, DONNELLY KL, SHAH SK et al: Inhibi-tion of nitric oxide synthase by benzoxazolones. Bioorg. Med. Chem. Lett. (1997) 7:2887–2892.
  • SHEARER BG, LEE S, OPLINGER JA et al.: Substituted N-phenylisothioureas: potent inhibitors of human nitric oxide synthase with neuronal isoform selectivity. J. Med. Chem. (1997) 40:1901–1905.
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  • •One of the few references to NOS-binding proteins. This protein does not appear to bind at the site described in this application.
  • VENEMA VJ, JU H, ZOU R, VENEMA RC: Interaction of neuronal nitric-oxide synthase with caveolin-3 in skeletal muscle. J. Biol. Chem. (1997) 272:28187–28190.
  • •The binding of caveolins to cNOS may be similar to the bind-ing described in this application.
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  • ••A useful lead summary of NOS interactions with other cellu-lar elements.

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