90
Views
1
CrossRef citations to date
0
Altmetric
Key Paper Evaluation

Inhaled phosphodiesterase type 5 inhibitors for cystic fibrosis: a new therapy for systemic disease?

Evaluation of: Lubamba B, Lebacq J, Reychler G, et al. Inhaled phosphodiesterase type 5 inhibitors restore chloride transport in cystic fibrosis mice. Eur Respir J 37(1):72-78.

, MD PhD
Pages 713-715 | Published online: 24 Mar 2011

Bibliography

  • Rowe SM, Miller S, Sorscher EJ. Cystic fibrosis. N Engl J Med 2005;20(19):1992-2001
  • Poschet JF, Fazio JA, Timmins GS, Endosomal hyperacidification in cystic fibrosis is due to defective nitric oxide-cylic GMP signalling cascade. EMBO Rep 2006;7(5):553-9
  • Antoniu SA. PDE5 inhibitors for cystic fibrosis: can they also enhance chloride transport? Evaluation of: Lubamba B, Lecourt H, Lebacq J, et al. Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis. Am J Respir Crit Care Med 2008;177(5):506-15. Expert Opin Investig Drugs 2008;17(6):965-68
  • Lubamba B, Lecourt H, Lebacq J, Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis. Am J Respir Crit Care Med 2008;177(5):506-15
  • Lubamba B, Lebacq J, Reychler G, Inhaled phosphodiesterase type 5 inhibitors restore chloride transport in cystic fibrosis mice. Eur Respir J 2011;37(1):72-8
  • Poschet JF, Timmins GS, Taylor-Cousar JL, Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis. Am J Physiol Lung Cell Mol Physiol 2007;293(3):L712-19
  • Robert R, Carlile GW, Pavel C, Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect. Mol Pharmacol 2008;73(2):478-89

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.