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Drug Evaluations

Misoprostol for the prevention and treatment of postpartum hemorrhage

, MPH MSW, , MPH, & , MD MPH
Pages 235-250 | Published online: 11 Jan 2012

Bibliography

  • Khan KS, Wojdyla D, Say L, WHO analysis of causes of maternal death: a systematic review. Lancet 2006;367:1066-74
  • United Nations. The Millennium Development Goals Report 2009 [Online]. 2009. Available from: http://www.un.org/millenniumgoals/pdf/MDG%20Report%202009%20ENG.pdf [Last accessed 26 July 2009]
  • Akins S. Postpartum hemorrhage: a 90s approach to an age-old problem. J Nurse Midwifery 1994;39:123S-34S
  • Cohen WR. Postpartum uterine hemorrhage. In: Cherry SH, Merkatz IR, editors. Complications of pregnancy: medical, surgical, gynecologic, psychosocial and perinatal. 4th edittion. Williams & Wilkins; Baltimore: 1991. p. 1132-41
  • Maine D. Safe motherhood programs: options and issues. Volume 42 Columbia University; New York: 1993
  • Gülmezoglu AM, Villar J, Ngoc NT, WHO multicentre randomised study of misoprostol in the management of the third stage of labour. Lancet 2001;358:689-95
  • Gülmezoglu AM, Forna F, Villar J, Hofmeyr G. Prostaglandins for preventing postpartum haemorrhage. Cochrane Database Syst Rev 2007;3:CD000494
  • Alfirevic Z, Blum J, Walraven G, Prevention of postpartum haemorrhage with misoprostol. Int J Gyneacol Obstet 2007;99(Suppl 2):198-201
  • Mousa H, Alfirevic Z. Treatment for primary postpartum haemorrhage. Cochrane Database Syst Rev 2007;2007(1):1-25
  • Tsu VD, Shane B. New and underutilized technologies to reduce maternal mortality: call to action from a Bellagio workshop. Int J Gyneacol Obstet 2004;85(Suppl 1):S83-93
  • International Confederation of Midwives. International Federation of Gynaecologists and Obstetricians. Joint statement: management of the third stage of labour to prevent postpartum haemorrhage. J Midwifery Womens Health 2004;49:76-7
  • WHO DoMPS. WHO Recommendations for the Prevention of Postpartum Haemorrhage. World Health Organization; Geneva: 2007
  • Royal College of Obstetricians and Gynaecologists. Prevention and Management of Postpartum Haemorrhage. RCOG Green-top Guideline No. 52. Royal College of Obstetricians and Gynaecologists; London: 2009
  • Cotter AM, Ness A, Tolosa JE. Prophylactic oxytocin for the third stage of labour. Cochrane Database Syst Rev 2001(4):CD001808
  • McDonald SJ, Abbott JM, Higgins SP. Prophylactic ergometrine-oxytocin versus oxytocin for the third stage of labour. Cochrane Database of Systematic Reviews 2004; Issue 1 Art. No.: CD000201. DOI: 10.1002/14651858.CD000201.pub2.
  • Çalişkan E, Dilbaz B, Meydanli MM, Oral misoprostol for the third stage of labor: a randomized controlled trial. Obstet Gynaecol 2003;101:921-8
  • Çalişkan E, Meydanli MM, Dilbaz B, Is rectal misoprostol really effective in the treatment of third stage of labor? A randomized controlled trial. Am J Obstet Gynecol 2002;187:1038-45
  • Walraven G, Blum J, Dampha Y, misoprostol in the management of the third stage of labour in the home delivery setting in rural Gambia: a randomised controlled trial. BJOG 2005;112(9):1277
  • Garg P, Batra S, Gandhi G. Oral misoprostol versus injectable Methylergometrine in management of the third stage of labor. Int J Gynaecol Obstet 2005;91:160-1
  • Oboro VO, Tabowei TO. A randomised controlled trial of misoprostol versus oxytocin in the active management of the third stage of labour. J Obstet Gynaecol 2003;23:13-16
  • Ng PS, Chan AS, Sin WK, A multicentre randomized controlled trial of oral misoprostol and i.m. syntometrine in the management of the third stage of labor. Hum Reprod 2001;16:31-5
  • Amant F, Spitz B, Timmerman D, misoprostol compared with Methylergometrine for the prevention of postpartum hemorrhage: a double-blinded randomized trial. BJOG 1999;106(10):1066-70
  • Soltan MH, El-Gendi E, Imam HH, Fathi O. Different doses of sublingual misoprostol versus Methylergometrine for the prevention of atonic postpartum haemorrhage. Int J Health Sci 2007;1:229-36
  • Lam H, Tang OS, Lee CP, Ho PC. A pilot-randomized comparison of sublingual misoprostol with syntometrine on the blood loss in third stage of labor. Acta Obstet Gynaecol Scand 2004;83:647-50
  • Gupta B, Jain V, Aggarwal N. Rectal misoprostol versus oxytocin in the prevention of postpartum hemorrhage—A pilot study. Int J Gynaecol Obstet 2006;94(Suppl 2):139-40
  • Chandhiok N, Dhillon B, Datey S, Oral misoprostol for prevention of postpartum hemorrhage by paramedical workers in India. Intl J Gynaecol Obstet 2006;92:170-5
  • Afolabi EO, Kuti O, Orji EO, Ogunniyi SO. Oral misoprostol versus intramuscular oxytocin in the active management of the third stage of labor. Singapore Med J 2010;51(3):207-11
  • Baskett TF, Persad VL, Clough HJ, Young DC. misoprostol versus oxytocin for the reduction of postpartum blood loss. Int J Gynaecol Obstet 2007;97:2-5
  • Ng PS, Lai CY, Sahota DS, Yuen PM. A double-blind randomized controlled trial of oral misoprostol and intramuscular syntometrine in the management of the third stage of labor. Gynecol Obstet Invest 2007;63:55-60
  • Zachariah E, Naidu M, Seshadri L. Oral misoprostol in the third stage of labor. Int J Gynaecol Obstet 2006;92:23-6
  • Kundodyiwa TW, Majoko F, Rusakaniko S. misoprostol versus oxytocin in the third stage of labor. Int J Gynaecol Obstet 2001;75:235-41
  • Walley RL, Wilson JB, Crane JMG, A double-blind placebo controlled randomised trial of misoprostol and oxytocin in the managemetn of the third stage of labour. BJOG 2000;107:1111-15
  • Vaid A, Dadhwal V, Mittal S, A randomized controlled trial of prophylactic sublingual misoprostol versus intramuscular methyl-ergometrine versus intramuscular 15-methyl PGF2alpha in active management of third stage of labor. Arch Gynecol Obstet 2009;280:893-7
  • Verma P, Aggarwal N, Jain V, Suri V. A double-blind randomized controlled trial to compare sublingual misoprostol with Methylergometrine for prevention of postpartum hemorrhage. Int J Gynaecol Obstet 2006;94(Suppl 2):S137-8
  • Vimala N, Mittal S, Kumar S, Sublingual misoprostol versus Methylergometrine for active management of the third stage of labor. Int J Gynaecol Obstet 2004;87:1-5
  • Bugalho A, Daniel A, Faundes A, Cunha M. misoprostol for prevention of postpartum hemorrhage. Int J Gynaecol Obstet 2001;73:1-6
  • Bamigboye AA, Merrell DA, Hofmeyr GJ, Mitchell R. Randomized comparison of rectal misoprostol with syntometrine for management of the third stage of labor. Acta Obstet Gynaecol Scand 1998;77:178-81
  • Cook CM, Spurrett B, Murray H. A randomized clinical trial comparing oral misoprostol with synthetic oxytocin or syntometrine in the third stage of labour. Aust NZ Obstet Gynaecol 1999;39:414-19
  • Gerstenfeld TS, Wing DA. Rectal misoprostol versus intravenous oxytocin for the prevention of postpartum hemorrhage after vaginal delivery. Am J Obstet Gynecol 2001;185:878-82
  • Enakpene CA, Morhason-Bello IO, Enakpene EO, Oral misoprostol for the prevention of primary post-partum hemorrhage during third stage of labor. J Obstet Gynaecol Res 2007;33:810-17
  • El-Refaey H, Nooh R, O'Brien P, The misoprostol third stage of labour study: a randomised controlled comparison between orally administered misoprostol and standard management. BJOG 2000;107:1104-10
  • Nasr A, Shahin AY, Elsamman AM, Rectal misoprostol versus intravenous oxytocin for prevention of postpartum hemorrhage. Int J Gynaecol Obstet 2009;105:244-7
  • Penaranda WA, Arrieta OB, Yances BR. Manejo activo del alumbramiento con misoprostol sublingual: un estudio clinico controlado en el hospital de maternidad rafael calvo de cartagena. Revista Colombiana de Obstetricay Ginecologia 2002;53:87-91
  • Parsons SM, Walley RL, Crane JMG, Oral misoprostol versus oxytocin in the management of the third stage of labour. J Obstet Gynaecol Can 2006;28:20-6
  • Diab KM, Ramy AR, Yehia MA. The use of rectal misoprostol as active pharmacological management of the third stage of labor. J Obstet Gynaecol Res 1999;25:327-32
  • Sloan NL, Durocher J, Aldrich T, What measured blood loss tells us about postpartum bleeding: a systematic review. BJOG 2010;117:788-800
  • Miller S, Tudor C, Thorsten V, Randomized double masked trial of Zhi Byed 11, a Tibetan traditional medicine, versus misoprostol to prevent postpartum hemorrhage in Lhasa, Tibet. J Midwifery Womens Health 2009;54:133-41; e1
  • Nellore V, Mittal S, Dadhwal V. Rectal misoprostol vs. 15-methyl prostaglandin F2alpha for the prevention of postpartum hemorrhage. Int J Gynaecol Obstet 2006;94:45-6
  • Hofmeyr JG, Gülmezoglu AM. misoprostol for the prevention and treatment of postpartum haemorrhage. Best Practice & Research Clinical Obstetrics & Gynaecology 2008;22:1025-41.
  • Derman RJ, Kodkany BS, Goudar SS, Oral misoprostol in preventing postpartum haemorrhage in resource-poor communities: a randomised controlled trial. Lancet 2006;368:1248-53
  • Høj L, Cardoso P, Nielsen BB, Effect of sublingual misoprostol on severe postpartum hemorrhage in a primary health centre in Guinea-Bissau: randomized double blind clinical trial. BMJ 2005;331(7519):723
  • Mobeen N, Durocher J, Zuberi NF, Administration of misoprostol by trained traditional birth attendants to prevent postpartum haemorrhage in homebirths in Pakiston: a randomised placebo-controlled trial. BJOG 2011;118:353-61
  • Benchimol M, Gondry J, Mention J-E, Place du misoprostol dans la direction de la delivrance. J Gynaecol Obstet Biol Reprod 2001;30:576-83
  • Hofmeyr GJ, Nikodem C, de Jager M, Drakely A. Side-effects of oral misoprostol in the third stage of labour—a randomised placebo-controlled trial. S Afr Med J 2001;91:41-4
  • Surbek DV, Fehr PM, Hosli I, Holzgreve W. Oral misoprostol for third stage of labor: a randomized placebo-controlled trial. Obstret Gynaecol 1999;94:255-8
  • Hofmeyr JG, Nikodem VC, de Jager M, Gelbart BR. A randomized placebo controlled study of oral misoprostol in the third stage of labour. Br J Obstet Gynaecol 1998;105:971-5
  • Ozkaya O, Sezik M, Kaya H, Placebo-controlled randomized comparison of vaginal with rectal misoprostol in the prevention of postpartum hemorrhage. J Obstet Gynaecol Res 2005;31:389-93
  • Bamigboye AA, Hofmeyr GJ, Merrell DA. Rectal misoprostol in the prevention of postpartum hemorrhage: a placebo-controlled trial. Am J Obstet Gynecol 1998;179:1043-6
  • Hofmeyr GJ, Fawole B, Mugerwa K, Administration of 400 ug of misoprostol to augment routine active management of the third stage of labor. Int J Gynaecol Obstet 2011;112:98-102
  • Fawole AO, Sotiloye OS, Hunyinbo KI, A double-blind, randomized, placebo-controlled trial of misoprostol and routine uterotonics for the prevention of postpartum hemorrhage. Int J Gynaecol Obstet 2011;112:107-11
  • Hofmeyr GJ, Gülmezoglu AM, Novikova N, misoprostol to prevent and treat postpartum haemorrhage: a systematic review and meta-analysis of maternal deaths and dose-related effects. Bull World Health Organ 2009;87:666-77
  • Chong YS, Chua S, Shen L, Arulkumaran S. Does the route of administration of misoprostol make a difference? The uterotonic effect and side effects of misoprostol given by different routes after vaginal delivery. Obstet Gynecol 2004;131:191-8
  • Tang OS, Schweer H, Seyberth HW, Pharmacokinetics of different routes of administration of misoprostol. Hum Reprod 2002;17:332-6
  • Zieman M, Fong SK, Benowitz NL, Absorption kinetics of misoprostol with oral or vaginal administration. Obstet Gynecol 1997;90:88-91
  • Durocher J, Bynum J, León W, High fever following postpartum administration of sublingual misoprostol. BJOG 2010;117:845-52
  • Chong YS, Chua S, Arulkumaran S. Severe hypothermia following oral misoprostol in the immediate postpartum period. Obstet Gynaecol 1997;90:703-4
  • Lumbiganon P, Villar J, Piaggio G, Side effects of misoprostol during the first 24 hours after administration in the third stage of labour. BJOG 2002;109:1222-6
  • Patted SS, Goudar SS, Naik VA, Side effects of oral misoprostol for the prevention of post-partum haemorrhage: results of a community-based randomised controlled trial in rural India. J Matern Fetal Neonatal Med 2009;22:24-8
  • Winikoff B, Dabash R, Durocher J, Treatment of post-partum haemorrhage with sublingual misoprostol versus oxytocin in women not exposed to oxytocin during labour: a double-blind, randomised, non-inferiority trial. Lancet 2010;375:210-16
  • Blum J, Winikoff B, Raghavan S, Treatment of post-partum haemorrhage with sublingual misoprostol versus oxytocin in women receiving prophylactic oxytocin: a double-blind, randomised, non-inferiority trial. Lancet 2010;375:217-23
  • Lokugamage AU, Sullivan KR, Niculescu I, A randomized study comparing rectally administered misoprostol versus syntometrine combined with an oxytocin infusion for the cessation of primary postpartum hemorrhage. Acta Obstet Gynecol Scand 2001;80:835-9
  • Widmer M, Blum J, Hofmeyr GJ, misoprostol as an adjunct to standard uterotonics for treatment of post-partum haemorrhage: a multicentre, double-blind randomised trial. Lancet 2010;375:1808-13
  • Zuberi N, Durocher J, Sikander R, misoprostol in addition to routine treatment of postpartum hemorrhage: a hospital-based randomized controlled-trial in Karachi, Pakistan. BMC Pregnancy Childbirth 2008;8:40
  • Walraven G, Dampha Y, Bittaye B, misoprostol in the treatment of postpartum haemorrhage in addition to routine management: a placebo randomized controlled trial. BJOG 2004;111:1014-17
  • Hofmeyr GJ, Ferreira S, Nikodem VC, misoprostol for treating postpartum hemorrhage: a randomized controlled trial. BMC Pregnancy Childbirth 2004;4:16
  • World Health Organization. WHO Model List of Essential Medicines 17th edition [online] 2011. Available from: http://whqlibdoc.who.int/hq/2011/a95053_eng.pdf [Last accessed 13 October 2011]
  • Hofmeyr GJ, Walraven G, Gülmezoglu AM, misoprostol to treat postpartum hemorrhage: a systematic review. BJOG 2005;112:547-53

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