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Reviews

Novel investigational drugs mimicking exercise for the treatment of cachexia

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Bibliography

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● One of the most complete reviews on cancer cachexia and energy metabolism alterations

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● A very good survey of the relation between altered mitochondria and muscle protein breakdown.

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● This review clearly shows the effectiveness of exercise in correcting muscle wasting.

● This paper demonstrates the effect of PGC-1α modulations on mitophagy.

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●● The first demonstration that exercise can be mimicked by drugs.

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●● An elegant demonstration that PPARδ agonists improve muscle dystrophy.

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