Bibliography
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- •Seminal paper that is often cited as one of the basic tenets of immunology.
- KLING J: Gene transfer to the mothers of all cells. Na- ture Biotechnol (1996) 14:269.
- ••Good review article, indicating what problems lie ahead forgene therapy.
- JONES DRE, BUT TH, ANDERSON EM et al.: In utero hae- matopoietic stem cell transplantation: current perspectives and future potential. Bone Marrow Trans-plant. (1996) 18:831–837.
- ••Thorough review of the state of the art for in uterotransplan-tation. All cases recorded by mid-1996 are reported in this article and comment provided on the outcomes in each dis-ease category.
- JONES DRE, BUT TH: Fetal therapy: prospects for trans- plantation early in pregnancy. Mol. Med. Today (1998) 4:10–11.
- •Report of the Second International Symposium on In Utero Transplantation and Gene Therapy, held in Nottingham, UK, in September 1997. An up-to-date account of cases and outcomes and insights into current research in this area.
- JONES DRE, ANDERSON EM, EVANS AA, LIU DTY: Long-term storage of human fetal hematopoietic progenitor cells and their subsequent reconstitution - implica-tions for in utero transplantation. Bone Marrow Trans-plant. (1995) 16:297–301.
- ZANJANI ED, ASCENSAO JL, TAVASSOLI M: Liver-derived fetal hematopoietic stem cells selectively and prefer-entially home to the fetal bone marrow. Blood (1993) 81:399–404.
- •Seminal paper showing the route of engraftment of cells traansplanted in utero. Uses an animal model.
- FLAKE AW, PUCK JM, ALMEIDA-PORADA G et al.: Treat- ment of X-linked severe combined immunodeficiency by in utero transplantation of paternal bone marrow. New Engl. J. Med. (1996) 335:1806–1810.
- •First report of 100% success using JUT for SCID.
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- •Three cases of SCID transplanted in utero, again reporting success.
- ANDREANI M, MANNA M, LUCARELLI G et al: Persistence of mixed chimerism in patients transplanted for the treatment of thalassemia. Blood (1996) 87:3494–3499.
- ANDERSON EM, JONES DRE, LIU DTY, EVANS AA: Gesta-tional age and cell viability determine the effect of fro-zen storage on human fetal hematopoietic progenitor cell preparations. Fetal Diagn. Ther. (1996) 11:427–432.
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- •Important paper discussing the impact of ex vivo expansion protocols on the quality of stem cells (and by implication, the effects this will have on engraftment after a transplant procedure).
- SHIMIZU Y, OGAWA M, KOBAYASHI M, ALMEIDA-PORADA G, ZANJANI ED: Engraftment of cultured hu-man hematopoietic cells in sheep. Blood (1998) 91:3688–3692.
- GLUCKMAN E, ROCHA V, BOYER A et al.: Outcome ofcord-blood transplantation from related and unre-lated donors. New Engl. J. Med. (1997) 337:373–381.
- ZANJANI ED, ALMEIDA-PORADA G, LIVINGSTON AG, FLAKE AW, OGAWA M: Human bone marrow CD34(-) cells engraft in vivo and undergo multilineage expression that includes giving rise to CD34(+) cells. Exp. Hematol. (1998) 26:353–360.
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- •A successful foetal SCID patient transplanted in utero.
- FLAKE AW, ZANJANI ED: In utero hematopoietic stem cell transplantation. A status report. J. Am. Med. Assoc. (1997) 278:932–937.
- •A good review outlining the advantages and drawbacks of the various in utero protocols.
- ZANJANI ED, ASCENSAO JL, HARRISON MR, TAVASSOLIM: Ex vivo incubation with growth factors enhances the engraftment of fetal hematopoietic cells trans-planted in sheep fetuses. Blood (1992) 79:3045–3049.
- FLAKE AW, ZANJANI ED: In utero transplantation of he-matopoietic stem cells. Grit. Rev. Oncol. Hematol. (1993) 15:35–48.
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- WYNN RF, CROSS MA, HATTON C et al.: Accelerated telo-mere shortening in young recipients of allogeneic bone-marrow transplants. Lancet (1998) 351:178–181.
- ••Important data relating to the fate of stem cells after trans-plantation. Accelerated proliferation of these cells in the re-cipient could lead to their premature demise.
- SHAY JW: Accelerated telomere shortening in bone marrow recipients. Lancet (1998) 351:153–154.
- ••Good review of the telomere theory: reasons why stem cellsare restricted to a finite number of cell divisions and how this process could be accelerated in transplant recipients.
- LANSDORP PM: Telomere length and proliferation po- tential of hematopoietic stem cells. J. Cell Sci. (1995) 108:1–6.
- ••Excellent report on telomeres in stem cells from varioussources and the implications for transplantation. The supe-rior qualities of foetal stem cells are clearly shown.