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Clinical Trial Evaluation

Interest of lasofoxifene in the treatment of osteoporosis

Evaluation of ‘Lasofoxifene in postmenopausal women with osteoporosis.’ N Engl J Med 2010;362:686-96

Pages 1773-1775 | Published online: 06 May 2010

Bibliography

  • Cummings SR, Ensrud K, Delmas PD, Lasofoxifene in postmenopausal women with osteoporosis. N Engl J Med 2010;362:686-96
  • Ettinger B, Black DM, Mitlak BH, Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators. JAMA 1999;282:637-45
  • McClung M, Siris E, Cummings S, Prevention of bone loss in postmenopausal women treated with lasofoxifene compared with raloxifene. Menopause 2006;13:377-86
  • Delmas PD, Calvo G, Boers M, The use of placebo-controlled and non-inferiority trials for the evaluation of new drugs in the treatment of postmenopausal osteoporosis. Osteoporos Int 2002;13:1-5
  • Reginster JY, Abadie E, Delmas P, Recommendations for an update of the current (2001) regulatory requirements for registration of drugs to be used in the treatment of osteoporosis in postmenopausal women and in men. Osteoporos Int 2006;17:1-7

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