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Miscellaneous

Hormonal therapies in acne

Pages 865-874 | Published online: 25 Feb 2005

Bibliography

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  • •The classic first paper to show the importance of male hormones in acne
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  • •Hirsutism improved equally with spironolactone, cyproterone acetate and flutarnide, but returned within 1 year after treatment was stopped.
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  • •A succinct review of topical antiandrogens.
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  • •A 60% reduction in sebaceous gland size was observed in this study of Syrian hamster ear sebaceous gland model, with no systemic effect.
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  • •Topical inocoterone produced 26% reduction of inflammatory acne lesions compared to 13% reduction with placebo.
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  • ••This review is an invaluable resource forphysicians wishing to use oral contraceptives in their patients. Indications, risks, precautions and contraindications are presented.

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