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Drug Evaluation

Bortezomib for multiple myeloma

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Pages 1337-1346 | Published online: 29 Jun 2006

Bibliography

  • PHEKOO KJ, SCHEY SA, RICHARDS MA et al.: A population study to define the incidence and survival of multiple myeloma in a National Health Service Region in UK. Br. J. Haematol. (2004) 127(3):299-304.
  • CHILD JA, MORGAN GJ, DAVIES FE et al.: High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N. Engl. J. Med. (2003) 348(19):1875-1883.
  • SMITH A, WISLOFF F, SAMSON D: Guidelines on the diagnosis and management of multiple myeloma 2005. Br. J. Haematol. (2006) 132(4):410-451.
  • HIDESHIMA T, CHAUHAN D, RICHARDSON P, ANDERSON KC: Identification and validation of novel therapeutic targets for multiple myeloma. J. . Oncol. (2005) 23(26):6345-6350.
  • CAVENAGH JD, OAKERVEE H: Thalidomide in multiple myeloma: current status and future prospects. Br. J. Haematol. (2003) 120(1):18-26.
  • CAVO M, ZAMAGNI E, TOSI P et al.: Superiority of thalidomide and dexamethasone over vincristine-doxorubicindexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma. Blood (2005) 106(1):35-39.
  • PALUMBO A, BRINGHEN S, CARAVITA T et al.: Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial. Lancet 367(9513):825-831.
  • RICHARDSON PG, SCHLOSSMAN RL, WELLER E et al.: Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma. Blood (2002) 100(9):3063-3067.
  • DIMOPOULOS MA, SPENCER A, ATTAL M et al.: Study of lenalidomide plus dexamethasone versus dexamethasone alone in relapsed or refractory multiple myeloma (MM): results of a Phase III study (MM-010). Blood (2005) 106(11):6 Abstract.
  • ADAMS J: The development of proteasome inhibitors as anticancer drugs. Cancer Cell (2004) 5(5):417-421.
  • ADAMS J, PALOMBELLA VJ, SAUSVILLE EA et al.: Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res. (1999) 59(11):2615-2622.
  • ADAMS J: Proteasome inhibition in cancer: development of PS-341. Semin. Oncol. (2001) 28(6):613-619.
  • MITSIADES N, MITSIADES CS, POULAKI V et al.: Molecular sequelae of proteasome inhibition in human multiple myeloma cells. Proc Natl Acad Sci USA (2002) 99(22):14374-14379.
  • HIDESHIMA T, RICHARDSON P, CHAUHAN D et al.: The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res. (2001) 61(7):3071-3076.
  • MILLENIUM PHARMACEUTICALS I: Velcade Investigator’s Brochure (2005).
  • HAMILTON AL, EDER JP, PAVLICK AC et al.: Proteasome inhibition with bortezomib (PS-341): a Phase I study with pharmacodynamic end points using a day 1 and day 4 schedule in a 14-day cycle. J. Clin. Oncol. (2005) 23(25):6107-6116.
  • PAPANDREOU CN, DALIANI DD, NIX D et al.: Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J. Clin. Oncol. (2004) 22(11):2108-2121.
  • JAGANNATH S, BARLOGIE B, BERENSON JR et al.: Bortezomib in recurrent and/or refractory multiple myeloma. Initial clinical experience in patients with impared renal function. Cancer (2005) 103(6):1195-1200.
  • CHANAN-KHAN AA, RICHARDSON P, LONIAL S et al.: Safety and efficacy of bortezomib in multiple myeloma patients with renal failure requiring dialysis. Blood (2005) 106(11):2550 Abstract.
  • NIX D, RYAN DP, EDER JP et al.: Pharmacokinetics of gemcitabine and the proteasome inhibitor bortezomib (formerly PS-341) in adult patients with solid malignancies. Proceedings of the Annual Meeting of the American Association of Cancer Research (2003) Abstract 5347.
  • SUPKO JG, EDER JP, LYNCH RM et al.: Pharmacokinetics of irinotecan and the proteasome inhibitor bortezomib in adult patients with solid malignanicies. Proceedings of the Annual Meeting of the American Association of Clinical Oncology (2003) Abstract 544.
  • PEKOL T, DANIELS JS, LABUTTI J et al.: Human metabolism of the proteasome inhibitor bortezomib: identification of circulating metabolites. Drug Metab. Dispos. (2005) 33(6):771-777.
  • LU C, GALLEGOS R, LI P et al.: Investigation of drug-drug interaction potential of bortezomib in vivo in female sprague-dawley rats and in vitro in human liver microsomes. Drug Metab. Dispos. (2006) 34(4):702-708.
  • ORLOWSKI RZ, STINCHCOMBE TE, MITCHELL BS et al.: Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies. J. Clin. Oncol. (2002) 20(22):4420-4427.
  • AGHAJANIAN C, SOIGNET S, DIZON DS et al.: A Phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies. Clin. Cancer Res. (2002) 8(8):2505-2511.
  • DY GK, THOMAS JP, WILDING G et al.: A Phase I and pharmacologic trial of two schedules of the proteasome inhibitor, PS-341 (bortezomib, velcade), in patients with advanced cancer. Clin. Cancer Res. (2005) 11(9):3410-3416.
  • BLANEY SM, BERNSTEIN M, NEVILLE K et al.: Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: a Children’s Oncology Group study (ADVL0015). J. Clin. Oncol. (2004) 22(23):4804-4809.
  • CORTES J, THOMAS D, KOLLER C et al.: Phase I study of bortezomib in refractory or relapsed acute leukemias. Clin. Cancer Res. (2004) 10(10):3371-3376.
  • RICHARDSON PG, BARLOGIE B, BERENSON J et al.: A Phase II study of bortezomib in relapsed, refractory myeloma. N. Engl. J. Med. (2003) 348(26):2609-2617.
  • BLADE J, SAMSON D, REECE D et al.: Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant. Br. J. Haematol. (1998) 102(5):1115-1123.
  • RICHARDSON PG, BARLOGIE B, BERENSON J et al.: Extended follow-up of a Phase II trial in relapsed, refractory multiple myeloma:: final time-to-event results from the SUMMIT trial. Cancer (2006) 106(6):1316-1319.
  • JAGANNATH S, BARLOGIE B, BERENSON J et al.: A Phase II study of two doses of bortezomib in relapsed or refractory myeloma. Br. J. Haematol. (2004) 127(2):165-172.
  • BERENSON JR, JAGANNATH S, BARLOGIE B et al.: Safety of prolonged therapy with bortezomib in relapsed or refractory multiple myeloma. Cancer (2005) 104(10):2141-2148.
  • MITSIADES N, MITSIADES CS, RICHARDSON PG et al.: The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood (2003) 101(6):2377-2380.
  • MA MH, YANG HH, PARKER K et al.: The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clin. Cancer Res. (2003) 9(3):1136-1144.
  • HAROUSSEAU JL, ATTAL M, LELEU X et al.: Bortezomib plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma. Preliminary results of an IFM Phase II Study. Haematologica (2005) 90(s1):148.
  • JAGANNATH S, DURIE BG, WOLF J et al.: Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma. Br. J. Haematol. (2005) 129(6):776-783.
  • KROPFF M, BISPING G, LIEBISCH P et al.: Bortezomib in combination with high-dose dexamethasone and continuous low-dose oral cyclophosphamide for relapsed multiple myeloma. Blood (2005) 106(11):2549 Abstract.
  • OAKERVEE HE, POPAT R, CURRY N et al.: PAD combination therapy (PS-341/bortezomib, doxorubicin and dexamethasone) for previously untreated patients with multiple myeloma. Br. J. Haematol. (2005) 129(6):755-762.
  • POPAT R, OAKERVEE HE, CURRY N et al.: Reduced dose PAD combination therapy (PS-341/bortezomib, adriamycin and dexamethasone) for previously untreated patients with multiple myeloma. Blood (2005) 106(11):2554 Abstract.
  • BARLOGIE B, RASMUSSEN E, SHAUGHNESSY J et al.: Total therapy for newly diagnosed multiple myeloma: the Arkansas experience with 1000 patients treated with total therapy 1,2 and 3. Haematologica (2005) 90(s1):19.
  • MATEOS MV, BLADE J, DIAZ MEDIAVILLA J et al.: A Phase I/II national, multi-center, open-label study of velcade plus melphalan and prednisone (V-MP) in elderly untreated multiple myeloma patients. Haematologica (2005) 90(s1):149.
  • POPAT R, GOFF L, OAEKERVEE HE, CAVENAGH JD, JOEL SP: Changes in Mcl-1 and Bim expression with bortezomib and melphalan therapy for multiple myeloma. Blood (2005) 106(11):2481 Abstract.
  • BERENSON JR, YANG HH, SADLER K et al.: Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma. J. Clin. Oncol. (2006) 24(6):937-944.
  • POPAT R, OAKERVEE HE, FOOT N et al.: A Phase I/II study of bortezomib and low dose intravenous melphalan (BM) for relapsed multiple myeloma. Blood (2005) 106(11):2555 Abstract.
  • RICHARDSON P, SCHLOSSMAN R, MUNSHI N et al.: A Phase I trial of lenalidomide (REVLIMID(R)) with bortezomib (VELCADE(R)) in relapsed and refractory multiple myeloma. Blood (2005) 106(11):365 Abstract.
  • O’CONNOR OA: Targeting histones and proteasomes: new strategies for the treatment of lymphoma. J. Clin. Oncol. (2005) 23(26):6429-6436.
  • GOY A, YOUNES A, MCLAUGHLIN P et al.: Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin’s lymphoma. J. Clin. Oncol. (2005) 23(4):667-675.
  • O’CONNOR OA, WRIGHT J, MOSKOWITZ C et al.: Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin’s lymphoma and mantle cell lymphoma. J. Clin. Oncol. (2005) 23(4):676-684.
  • STRAUSS SJ, MAHARAJ L, HOARE S et al.: Bortezomib therapy in patients with relapsed or refractory lymphoma: potential correlation of in vitro sensitivity and tumor necrosis factor alpha response with clinical activity. J. Clin. Oncol. (2006) 24(13):2105-2112.
  • YANAMANDRA N, COLACO NM, PARQUET NA et al.: Tipifarnib and bortezomib are synergistic and overcome cell adhesion-mediated drug resistance in multiple myeloma and acute myeloid leukemia. Clin. Cancer Res. (2006) 12(2):591-599.
  • MARKOVIC SN, GEYER SM, DAWKINS F et al.: A Phase II study of bortezomib in the treatment of metastatic malignant melanoma. Cancer (2005) 103(12):2584-2589.
  • PRICE N, DREICER R: Phase I/II trial of bortezomib plus docetaxel in patients with advanced androgen-independent prostate cancer. Clin Prostate Cancer (2004) 3(3):141-143.
  • YANG CH, GONZALEZ-ANGULO AM, REUBEN JM et al.: Bortezomib (VELCADE(R)) in metastatic breast cancer: pharmacodynamics, biological effects, and prediction of clinical benefits. Ann. Oncol. (2006) 17(5):813-817.
  • MACKAY H, HEDLEY D, MAJOR P et al.: A Phase II trial with pharmacodynamic endpoints of the proteasome inhibitor bortezomib in patients with metastatic colorectal cancer. Clin. Cancer Res. (2005) 11(15):5526-5533.
  • FANUCCHI MP, FOSSELLA F, FIDIAS P et al.: Bortezomib {+/-} docetaxel in previously treated patients with advanced non-small cell lung cancer (NSCLC): a Phase II study. J. Clin. Oncol. (2005) 23(16 Suppl.):7034 Abstract.
  • RICHARDSON PG, SONNEVELD P, SCHUSTER MW et al.: Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N. Engl. J. Med. (2005) 352(24):2487-2498.
  • LONIAL S, WALLER EK, RICHARDSON PG et al.: Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myeloma. Blood (2005) 106(12):3777-3784.
  • MIGUEL JFS, RICHARDSON P, SONNEVELD P et al.: Frequency, characteristics, and reversibility of peripheral neuropathy (PN) in the APEX Trial. Blood (2005) 106(11):366 Abstract.
  • COLSON K, DOSS DS, SWIFT R, TARIMAN J, THOMAS TE: Bortezomib, a newly approved proteasome inhibitor for the treatment of multiple myeloma: nursing implications. Clin J Oncol Nurs (2004) 8(5):473-480.
  • MIYAKOSHI S, KAMI M, YUJI K et al.: Severe pulmonary complications in Japanese patients after bortezomib treatment for refractory multiple myeloma. Blood (2006) 107(9):3492-3494.
  • BARLOGIE B, TRICOT G, ANAISSIE E et al.: Thalidomide and hematopoietic-cell transplantation for multiple myeloma. N. Engl. J. Med. (2006) 354(10):1021-1030.
  • RICHARDSON P, CHANAN-KHAN A, SCHLOSSMAN R et al.: A multicenter Phase II trial of bortezomib in patients with previously untreated multiple myeloma: efficacy with manageable toxicity in patients with unexpectedly high rates of baseline peripheral neuropathy. Blood (2005) 106(11):2548 Abstract.
  • CHAUHAN D, CATLEY L, LI G et al.: A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib. Cancer Cell (2005) 8(5):407-419.
  • MITSIADES CS, MITSIADES NS, MCMULLAN CJ et al.: Antimyeloma activity of heat shock protein-90 inhibition. Blood (2006) 107(3):1092-1100.
  • BAGUST A, HAYCOX AR, BOLAND A et al.: Economic evaluation of bortezomib (velcade) for relapsed and refractory multiple myeloma. Blood (2004) 104(11):268.

Website

  • http://www.ukmi.nhs.uk/NewMaterial/Secure/BortezomibRGB.pdf Bortezomib for relapsed and refractory multiple myeloma. National Prescribing Centre, 2004. Accessed 9 June, 2006.

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