Bibliography
- Laughlin NJ, Eapen M, Rubinstein P, Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia. N Engl J Med 2004;351:2265-75
- Rocha V, Labopin M, Sanz G, Transplants of umbilical-cord blood or marrow from unrelated donors in adults with acute leukemia. N Engl J Med 2004;351:2276-85
- Eapen M, Rubinstein P, Zhang MJ, Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukemia: a comparison study. Lancet 2007;369:1947-54
- Rubinstein P, Stevens C. An empirical analysis of the probability of finding a well-matched cord blood unit with adequate cell dose [abstract]. Fourth Annual Cord Blood Transplantation Symposium, Los Angeles; 2006. Biol Blood Marrow Transplant 2007;12:1212
- Laughlin MJ, Barker J, Bambach B, Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors. N Engl J Med 2001;344:1815-22
- Rubinstein P, Stevens CE. Placental blood for bone marrow replacement: the New York Blood Center's program and clinical results. Baillieres Best Pract Res Clin Haematol 2000;13:565-84
- Robinson S, Niu T, de Lima M, Ex vivo expansion of umbilical cord blood. Cytotherapy 2005;7:243-50
- Hofmeister CC, Zhang J, Knight KL, Ex vivo expansion of umbilical cord blood stem cells for transplantation: growing knowledge from the hematopoietic niche. Bone Marrow Transplant 2007;39:11-23
- Andrade-Zaldivar H, Santos L, De Leon Rodriguez A. Expansion of human hematopoietic stem cells for transplantation: trends and perspectives. Cytotechnology 2008;56:151-60
- Qiu L, Meagher R, Welhausen S, Ex vivo expansion of CD34+ umbilical cord blood cells in a defined serum-free medium (QBSF-60) with early effect cytokines. J Hematother Stem Cell Res 1999;8:609-18
- Douay L. Experimental culture conditions are critical for ex vivo expansion of hematopoietic cells. J Hematother Stem Cell Res 2001;10:341-6
- Piacibello W, Gammaitoni L, Bruno S, Negative influence of IL3 on the expansion of human cord blood in vivo long-term repopulating stem cells. J Hematother Stem Cell Res 2000;9:945-56
- Koller MR, Manchel I, Maher RJ, Clinical-scale human umbilical cord blood cell expansion in a novel automated perfusion culture system. Bone Marrow Transplant 1998;21:653-63
- Astori G, Adami V, Mambrini G, Evaluation of ex vivo expansion and engraftment in NOD-SCID mice of umbilical cord blood CD34+ cells using the DIDECO ‘Pluricell System’. Bone Marrow Transplant 2005;35:1101-6
- Conneally E, Cashman J, Petzer A, Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scid/scid mice. Proc Natl Acad Sci USA 1997;94:9836-41
- McNiece IK, Almeida-Porada G, Shpall EJ, Ex vivo expanded cord blood cells provide rapid engraftment in fetal sheep but lack long-term engrafting potential. Exp Hematol 2002;30:612-6
- Von Drygalski A, Alespeiti G, Ren L, Murine bone marrow cells cultured ex vivo in the presence of multiple cytokine combinations lose radioprotective and long-term engraftment potential. Stem Cells Dev 2004;13:101-11
- Piacibello W, Sanavio F, Severino A, Engraftment in nonobese diabetic severe combined immunodeficiency mice of human CD34+ cord blood cells after ex vivo expansions: evidence for the amplification and self-renewal of repopulating stem cells. Blood 1999;93:3736-49
- Lewis ID, Almeida-Porada G, Du J, Umbilical cord blood cells capable of engrafting in primary, secondary, and tertiary xenogeneic hosts are preserved after ex vivo culture in a noncontact system. Blood 2001;97:3441-9
- Cordano A, Placko RP, Graham GG. Hypocuperemia and neutropenia in copper deficiency. Blood 1966;28:280-3
- Hirase N, Abe Y, Sadamura S, Anemia and neutropenia in a case of copper deficiency: role of copper in normal hematopoiesis. Acta Haematol 1992;87:195-7
- Zidar BL, Shadduck RK, Zeigler Z, Observations on the anemia and neutropenia of human copper deficiency. Am J Hematol 1997;3:177-85
- Koca E, Buyukasik Y, Cetiner D, Copper deficiency with increased hematogones mimicking refractory anemia with excess blasts. Leuk Res 2008;32:495-9
- Peled T, Landau E, Prus E, Cellular copper content modulates differentiation and self-renewal in cultures of cord blood-derived CD34+ cells. Br J Haematol 2002;116:655-61
- Peled T, Landau E, Mandel J, Linear polyamine copper chelator tetraethylenepentamine augments long-term ex vivo expansion of cord blood-derived CD34+ cells and increases their engraftment potential in NOD/SCID mice. Exp Hematol 2004;32:547-55
- Ishikawa F, Livingston AG, Minamiguchi H, Human cord blood long-tern engrafting cells are CD34+ CD38-. Leukemia 2003;17:904-6
- Henon P, Sovalat H, Becker M, Primordial role of CD34+38- cells in early and late trilineage haemaopoietic engraftment after autologous blood cell transplantation. Br J Haematol 1998;103:568-81
- Peled T, Glukhman E, Hasson N, Chelatable cellular copper modulates differentiation and self-renewal of cord blood-derived hematopoietic progenitor cells. Exp Hematol 2005;33:1092-100
- Hainaut P, Rolley N, Davies M, Modulation by copper of p53 conformation and sequence-specific DNA binding: role of Cu (II)/Cu (I) redox mechanism. Oncogene 1995;10:27-32
- Ostrakhovitch EA, Lordnejad MR, Schliess F, Copper ions strongly activate the phosphoinositide-3-kinase/Akt pathway independent of the generation of reactive oxygen species. Arch Biochem Biophys 2002;397:232-9
- Kang J, Lin C, Chen J, Copper induces histone hypoacetylation through directly inhibiting histone acetyltransferase activity. Chem Biol Interact 2004;148:115-23
- Prus E, Fibach E. Effect of the copper chelator tetraethylenepentamine on reactive oxygen species generation by human hematopoietic progenitor cells. Stem Cells Dev 2007;16:1053-6
- Peled T, Mandel J, Goudsmid RN, Pre-clinical development of cord blood-derived progenitor cell graft expanded ex vivo with cytokines and the polyamine copper chelator tetraethylenepentamine. Cythotherapy 2004;6:344-55
- Summers YJ, Heyworth C, deWynter EA, AC133+G0 cells from cord blood show a high incidence of long-term culture-initiating cells and a capacity for more than 100 million-fold amplification of colony-forming cells in vitro. Stem Cells 2004;22:704-15
- de Lima M, McMannis J, Gee A, Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: a phase I/II clinical trial. Bone Marrow Transplant 2008;41:771-8
- Pecora AL, Stiff P, Jennis A, Prompt and durable engraftment in two older adult patients with high risk chronic myelogenous leukemia (CML) using ex vivo expanded and unmanipulated unrelated umbilical cord blood. Bone Marrow Transplant 2000;25:797-9
- Jaroscak J, Goltry K, Smith A, Augmentation of umbilical cord blood (UCB) transplantation with ex vivo-expanded UCB cells: results of a phase I trial using the AastromReplicell System. Blood 2003;101:5061-67
- Shpall EJ, Quinones R, Giller R, Transplantation of ex vivo expanded cord blood. Biol Blood Marrow Transplant 2002;8:368-76
- Delaney C, Brashem-Stein C, Voorhies H, Notch-mediated expansion of human cord blood progenitor cells results in rapid myeloid reconstitution in vivo following myeloablative cord blood transplantation [abstract 212]. Blood 2008;112 11(a):85
- Efficacy and safety study of StemEx®, to treat subjects with high risk hematologic malignancies, following myeloablative therapy (ExCell). Bethesda Maryland US National Institutes of Health 2007. Available from: http://clinicaltrials.gov/ct2/show/NCT00469729?term=NCT00469729&rank=1 [Last accessed 16 September 2009]
- Majhail NS, Brunstein CG, Wagner JE. Double umbilical cord blood transplantation. Curr Opin Immunol 2006;18:571-5
- Gluckman E, Rocha V, Arcese W, Factors associated with outcomes of unrelated donor cord blood transplant: guidelines for donor choice. Exp Hematol 2004;32:397-407