Bibliography
- Ekberg H, Tedesco-Silva H, Demirbas A, Reduced exposure to calcineurin inhibitors in renal transplantation. N Engl J Med 2007;357(25):2562-75
- Halloran PF. Immunosuppressive drugs for kidney transplantation. N Engl J Med 2004;351(26):2715-29
- Nankivell BJ, Alexander SI. Rejection of the kidney allograft. N Engl J Med 2010;363(15):1451-62
- Dierselhuis M, Goulmy E. The relevance of minor histocompatibility antigens in solid organ transplantation. Curr Opin Organ Transplant 2009;14(4):419-25
- Wasowska BA. Mechanisms involved in antibody- and complement-mediated allograft rejection. Immunol Res 2010;47(1–3):25-44
- Thaunat O, Nicoletti A. Lymphoid neogenesis in chronic rejection. Curr Opin Organ Transplant 2008;13(1):16-19
- Racusen LC, Solez K, Colvin RB, The Banff 97 working classification of renal allograft pathology. Kidney Int 1999;55(2):713-23
- Uslu A, Nart A. Treatment of first acute rejection episode: systematic review of level I evidence. Transplant Proc 2011;43(3):841-6
- Brennan DC, Flavin K, Lowell JA, A randomized, double-blinded comparison of Thymoglobulin versus Atgam for induction immunosuppressive therapy in adult renal transplant recipients. Transplantation 1999;67(7):1011-18
- Webster AC, Pankhurst T, Rinaldi F, Chapman JR, Craig JC. Monoclonal and polyclonal antibody therapy for treating acute rejection in kidney transplant recipients: a systematic review of randomized trial data. Transplantation 2006;81(7):953-65
- Villamor N, Montserrat E, Colomer D. Mechanism of action and resistance to monoclonal antibody therapy. Semin Oncol 2003;30(4):424-33
- Hardinger KL. Rabbit antithymocyte globulin induction therapy in adult renal transplantation. Pharmacotherapy 2006;26(12):1771-83
- Zand MS. B-cell activity of polyclonal antithymocyte globulins. Transplantation 2006;82(11):1387-95
- Midtvedt K, Fauchald P, Lien B, Individualized T cell monitored administration of ATG versus OKT3 in steroid-resistant kidney graft rejection. Clin Transplant 2003;17(1):69-74
- Clark KR, Forsythe JL, Shenton BK, Administration of ATG according to the absolute T lymphocyte count during therapy for steroid-resistant rejection. Transpl Int 1993;6(1):18-21
- Delmonico FL, Nelson PW, Colvin RB, Cosimi AB. Immunologic monitoring of antithymocyte globulin treatment for acute allograft rejection. Transplant Proc 1984;16(6):1492-3
- Cosimi AB, Wortis HH, Delmonico FL, Russell PS. Randomized clinical trial of antithymocyte globulin in cadaver renal allograft recipients: importance of T cell monitoring. Surgery 1976;80(2):155-63
- Frampton JE, Wagstaff AJ. Alemtuzumab. Drugs 2003;63(12):1229-43
- Friend PJ, Hale G, Waldmann H, Campath-1M–prophylactic use after kidney transplantation. A randomized controlled clinical trial. Transplantation 1989;48(2):248-53
- Rai K, Hallek M. Future prospects for alemtuzumab (MabCampath). Med Oncol 2002;19(Suppl):S57-63
- Clatworthy MR, Sivaprakasam R, Butler AJ, Watson CJ. Subcutaneous administration of alemtuzumab in simultaneous pancreas-kidney transplantation. Transplantation 2007;84(12):1563-7
- Bloom DD, Hu H, Fechner JH, Knechtle SJ. T-lymphocyte alloresponses of Campath-1H-treated kidney transplant patients. Transplantation 2006;81(1):81-7
- Scarsi M, Bossini N, Malacarne F, The number of circulating recent thymic emigrants is severely reduced 1 year after a single dose of alemtuzumab in renal transplant recipients. Transpl Int 2010;23(8):786-95
- Cantarovich D, Le Mauff B, Hourmant M, Anti-interleukin 2 receptor monoclonal antibody in the treatment of ongoing acute rejection episodes of human kidney graft–a pilot study. Transplantation 1989;47(3):454-7
- Shield CF III, Cosimi AB, Tolkoff-Rubin N, Use of antithymocyte globulin for reversal of acute allograft rejection. Transplantation 1979;28(6):461-4
- Hoitsma AJ, van Lier HJ, Reekers P, Koene RA. Improved patient and graft survival after treatment of acute rejections of cadaveric renal allografts with rabbit antithymocyte globulin. Transplantation 1985;39(3):274-9
- Theodorakis J, Schneeberger H, Illner WD, Aggressive treatment of the first acute rejection episode using first-line anti-lymphocytic preparation reduces further acute rejection episodes after human kidney transplantation. Transpl Int 1998;11(Suppl 1):S86-9
- Glass NR, Miller DT, Sollinger HW, Belzer FO. A Comparative-Study of Steroids and Heterologous Anti-Serum in the Treatment of Renal-Allograft Rejection. Transplant Proc 1983;15(1):617-21
- KDIGO. Clinical practice guideline for the care of kidney transplant recipients. Am J Transplant 2009;9(Suppl 3):S1-155
- Clatworthy MR, Friend PJ, Calne RY, Alemtuzumab (CAMPATH-1H) for the treatment of acute rejection in kidney transplant recipients: long-term follow-up. Transplantation 2009;87(7):1092-5
- Basu A, Ramkumar M, Tan HP, Reversal of acute cellular rejection after renal transplantation with Campath-1H. Transplant Proc 2005;37(2):923-6
- Hesse UJ, Wienand P, Baldamus C, Arns W. Preliminary results of a prospectively randomized trial of ALG vs OKT3 for steroid-resistant rejection after renal transplantation in the early postoperative period. Transplant Proc 1990;22(5):2273-4
- Mariat C, Alamartine E, Diab N, A randomized prospective study comparing low-dose OKT3 to low-dose ATG for the treatment of acute steroid-resistant rejection episodes in kidney transplant recipients. Transpl Int 1998;11(3):231-6
- Thomas PG, Ishihara K, Vaidya S, Gugliuzza KK. Campath and renal transplant rejection. Clin Transplant 2004;18(6):759-61
- Csapo Z, avides-Viveros C, Podder H, Pollard V, Kahan BD. Campath-1H as rescue therapy for the treatment of acute rejection in kidney transplant patients. Transplant Proc 2005;37(5):2032-6
- Upadhyay K, Midgley L, Moudgil A. Safety and efficacy of alemtuzumab in the treatment of late acute renal allograft rejection. Pediatr Transplant 2011;16(3):286-93
- Ferran C, Sheehan K, Dy M, Cytokine-related syndrome following injection of anti-CD3 monoclonal antibody: further evidence for transient in vivo T cell activation. Eur J Immunol 1990;20(3):509-15
- Hanaway MJ, Woodle ES, Mulgaonkar S, Alemtuzumab induction in renal transplantation. N Engl J Med 2011;364(20):1909-19
- Popow I, Leitner J, Majdic O, Assessment of batch to batch variation in polyclonal antithymocyte globulin preparations. Transplantation 2012;93(1):32-40
- Regan JF, Lyonnais C, Campbell K, Smith LV, Buelow R. Total and active thymoglobulin levels: effects of dose and sensitization on serum concentrations. Transpl Immunol 2001;9(1):29-36
- Prin Mathieu C, Renoult E, Kennel De March A, Serum anti-rabbit and anti-horse IgG, IgA, and IgM in kidney transplant recipients. Nephrol Dial Transplant 1997;12(10):2133-9
- Regan J, Campbell K, van Smith L, Characterization of anti-thymoglobulin, anti-Atgam and anti-OKT3 IgG antibodies in human serum with an 11-min ELISA. Transpl Immunol 1997;5(1):49-56
- Bielory L, Wright R, Nienhuis AW, Young NS, Kaliner MA. Antithymocyte globulin hypersensitivity in bone marrow failure patients. JAMA 1988;260(21):3164-7
- Hale G, Rebello P, Brettman LR, Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration. Blood 2004;104(4):948-55
- Matteson EL, Yocum DE, St Clair EW, Treatment of active refractory rheumatoid arthritis with humanized monoclonal antibody CAMPATH-1H administered by daily subcutaneous injection. Arthritis Rheum 1995;38(9):1187-93
- Schnitzer TJ, Yocum DE, Michalska M, Subcutaneous administration of CAMPATH-1H: clinical and biological outcomes. J Rheumatol 1997;24(6):1031-6
- Cossburn M, Pace AA, Jones J, Autoimmune disease after alemtuzumab treatment for multiple sclerosis in a multicenter cohort. Neurology 2011;77(6):573-9
- Kirk AD, Hale DA, Swanson SJ, Mannon RB. Autoimmune thyroid disease after renal transplantation using depletional induction with alemtuzumab. Am J Transplant 2006;6(5 Pt 1):1084-5
- Jones JL, Phuah CL, Cox AL, IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H). J Clin Invest 2009;119(7):2052-61
- Margreiter R, Klempnauer J, Neuhaus P, Alemtuzumab (Campath-1H) and tacrolimus monotherapy after renal transplantation: results of a prospective randomized trial. Am J Transplant 2008;8(7):1480-5
- Peleg AY, Husain S, Kwak EJ, Opportunistic infections in 547 organ transplant recipients receiving alemtuzumab, a humanized monoclonal CD-52 antibody. Clin Infect Dis 2007;44(2):204-12
- Cherikh WS, Kauffman HM, McBride MA, Association of the type of induction immunosuppression with posttransplant lymphoproliferative disorder, graft survival, and patient survival after primary kidney transplantation. Transplantation 2003;76(9):1289-93
- Bustami RT, Ojo AO, Wolfe RA, Immunosuppression and the risk of post-transplant malignancy among cadaveric first kidney transplant recipients. Am J Transplant 2004;4(1):87-93
- Caillard S, Dharnidharka V, Agodoa L, Bohen E, Abbott K. Posttransplant lymphoproliferative disorders after renal transplantation in the United States in era of modern immunosuppression. Transplantation 2005;80(9):1233-43
- Kaufman DB, Leventhal JR, Axelrod D, Alemtuzumab induction and prednisone-free maintenance immunotherapy in kidney transplantation: comparison with basiliximab induction–long-term results. Am J Transplant 2005;5(10):2539-48
- Muthusamy AS, Vaidya AC, Sinha S, Alemtuzumab induction and steroid-free maintenance immunosuppression in pancreas transplantation. Am J Transplant 2008;8(10):2126-31
- Kirk AD, Cherikh WS, Ring M, Dissociation of depletional induction and posttransplant lymphoproliferative disease in kidney recipients treated with alemtuzumab. Am J Transplant 2007;7(11):2619-25
- Toso C, Edgar R, Pawlick R, Effect of different induction strategies on effector, regulatory and memory lymphocyte sub-populations in clinical islet transplantation. Transpl Int 2009;22(2):182-91
- Buggins AG, Mufti GJ, Salisbury J, Peripheral blood but not tissue dendritic cells express CD52 and are depleted by treatment with alemtuzumab. Blood 2002;100(5):1715-20
- Zhang PL, Pennington JR, Prichard JW, CD52 antigen may be a therapeutic target for eosinophilic rhinosinusitis. Ann Clin Lab Sci 2007;37(2):148-51
- Santos DD, Hatjiharissi E, Tournilhac O, CD52 is expressed on human mast cells and is a potential therapeutic target in Waldenstrom's Macroglobulinemia and mast cell disorders. Clin Lymphoma Myeloma 2006;6(6):478-83
- Brett S, Baxter G, Cooper H, Repopulation of blood lymphocyte sub-populations in rheumatoid arthritis patients treated with the depleting humanized monoclonal antibody, CAMPATH-1H. Immunology 1996;88(1):13-19
- Vincenti F, Kirk AD. What's next in the pipeline. Am J Transplant 2008;8(10):1972-81
- Siemenow M, Brown SA, Thompson JS, Miller SD, Getts DR. TOL101; a novel alphabeta TCR targeting monoclonal antibody. Am J Transplant 2010;10:36
- Getts DR, Wiseman AC, Mulgaonkar S, Evaluating safety and efficacy of TOL101 induction to prevent kidney transplant rejection, part a interim analysis. Transpl Int 2011;24:93
- Sherry N, Hagopian W, Ludvigsson J, Teplizumab for treatment of type 1 diabetes (Protege study): 1-year results from a randomised, placebo-controlled trial. Lancet 2011;378(9790):487-97
- Bach JF. Anti-CD3 antibodies for type 1 diabetes: beyond expectations. Lancet 2011;378(9790):459-60
- Reichert JM. Antibody-based therapeutics to watch in 2011. MAbs 2011;3(1):76-99
- Kim YH, Duvic M, Obitz E, Clinical efficacy of zanolimumab (HuMax-CD4): two phase 2 studies in refractory cutaneous T-cell lymphoma. Blood 2007;109(11):4655-62
- Webster AC, Woodroffe RC, Taylor RS, Chapman JR, Craig JC. Tacrolimus versus ciclosporin as primary immunosuppression for kidney transplant recipients: meta-analysis and meta-regression of randomised trial data. BMJ 2005;331(7520):810
- Cai J, Terasaki PI. The current trend of induction and maintenance treatment in patient of different PRA levels: a report on OPTN/UNOS kidney Transplant Registry data. Clin Transpl 2010;45-52
- Korn T, Bettelli E, Oukka M, Kuchroo VK. IL-17 and Th17 Cells. Annu Rev Immunol 2009;27:485-517
- Yuan X, Paez-Cortez J, Schmitt-Knosalla I, A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy. J Exp Med 2008;205(13):3133-44
- Bluestone JA, Mackay CR, O'Shea JJ, Stockinger B. The functional plasticity of T cell subsets. Nat Rev Immunol 2009;9(11):811-16
- Hester J, Mills N, Shankar S, Th17 cells in alemtuzumab-treated patients: the effect of long-term maintenance immunosuppressive therapy. Transplantation 2011;91(7):744-50
- Lopez M, Clarkson MR, Albin M, Sayegh MH, Najafian N. A novel mechanism of action for anti-thymocyte globulin: induction of CD4+CD25+Foxp3+ regulatory T cells. J Am Soc Nephrol 2006;17(10):2844-53
- Bloom DD, Chang Z, Fechner JH, CD4+ CD25+ FOXP3+ regulatory T cells increase de novo in kidney transplant patients after immunodepletion with campath-1H. Am J Transplant 2008;8(4):793-802