Advanced search
Publication Cover
Expert Opinion on Biological Therapy Volume 3, 2003 - Issue 2
Submit an article Journal homepage
656
Views
49
CrossRef citations to date
0
Altmetric
Editorial

Alginate microcapsules for pancreatic islet cell graft immunoprotection: struggle and progress towards the final cure for type 1 diabetes mellitus

Riccardo Calafiore Department of Internal Medicine (Di.M.I.), University of Perugia, Via E. dal Pozzo, 06126 Perugia, Italy
Pages 201-205 | Published online: 03 Mar 2005

Bibliography

  • SHAPIRO AJM, LAKEY JTR, RYAN EA et al.: Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl. I Med (2000) 343:230–238.
  • LIM F, SUN AM: Microencapsulated islets as bioartificial endocrine pancreas. Science(1980) 210:908–910.
  • LANZA RP, BEYER AM, STARUK JE, CHICK WL: Biohybrid artificial pancreas: long-term function of discordant isletxenografts in streptozotocin-diabetic rats.Transplantation (1993) 56:1067–1072.
  • LUM ZP, TAI IP, KRESTOW M et al: Prolonged reversal of diabetic state in NOD mice by xenografts of microencapsulated rat islets. Diabetes (1991) 40:1511–1516.
  • LANZA RP, BORLAND RM, STARUK JE et al.: Transplantation of encapsulated canine islets into spontaneously diabetic BB/ Wor rats without immunosuppression.Endocrinology (1992) 131:637–642.
  • SUN Y, MAX, ZHOU DB et al.: Normalization of diabetes in spontaneouslydiabetic cynomologous monkeys by xenografts of microencapsulated porcine islets without immunosuppression. j Clin. Invest. (1996) 98:1417–1422.
  • COLTON CK: Implantable biohybrid artificial organs. Cell Trans. (1995) 4:415–422.
  • CALAFIORE R: Actual perspectives in biohybrid artificial pancreas for the therapy of type 1, insulin-dependent diabetes mellitus. Diabetes Metab. Rev (1998) 14(4):315–324.
  • SOON-SHIONG P, HEINTZ R, MERIDETH N et al.: Insulin-independence in a Type 1 diabetic patient after encapsulated islet transplantation.Lancet (1994) 343:950–951.
  • CALAFIORE R, BASTA G: Alginate/poly-L-ornithine microcapsules for pancreatic islet cell immunoprotection. In: Cell Encapsulation Technology and Therapeutics. Kuhtreiber WM, Lanza RP (Eds), Birkhauser, Ann Arbor, USA (1999):138–150.
  • CALAFIORE R: Bioartificial Pancreas. In: Polymeric Biomaterials (2nd edition). Dumitriu S (Ed.), Marcel Dekker, Inc., New York (2001):983–1005.
  • PATIENCE C, TAKEUCHI R, WEISS RA et al.: Infection of human cells by anendogenous retrovirus of pigs. Nat. Med.(1997) 3:282–287.
  • KUMAR G, TUCH BE, DENG YM et al.:Limiting potential infectious risks of transplanting insulin-producing cells into humans. Pathology (2002) 34:178–184.
  • DUVIVIER-KALI VF, OMER A, PARENT RI et al.: Complete protection of islets against allorejection by a simple barium-alginate membrane. Diabetes (2001) 50:1698–1705.
  • ORIVE G, HERNANDEZ RM, GASCON AR et al.: Encapsulated cell technology: from research to market. Trends Biotechnol (2002) 20:382–387.
  • CALAFIORE R, LUCA G, CALVITTI M et al.: Cellular support systems for alginate microcapsules containing islets as acomposite bioartificial pancreas. Ann. NY Acad. Sci (2001) 944:240–251.
  • STRAND BL, GASEROD 0, KULSENG B et al.: Alginate-polylysine-alginate microcapsules: effect of size reduction on capsule properties.Microencaps. (2002) 19:615–630.
  • CALAFIORE R, BASTA G, LUCA G et al: Alginate/polyaminoacidic coherent microcapsules for pancreatic islet graft immunoisolation in diabetic recipients.Ann. NY Acad. Sci. (1997) 831:313–322.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.