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Review

VEGF blocking therapy in the treatment of cancer

, &
Pages 263-276 | Published online: 03 Mar 2005

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  • ••Elegant paper on the role of VEGF in theangiogenic switch.
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  • ••Demonstrates increased efficacy withcombination therapy with VEGF blockade and low dose metronomic chemotherapy.
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  • ••Introduces the concept of metronomic chemotherapy to inhibit angiogenesis.
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References

  • ••Demonstrates the possibility of resistanceto antiangiogenic therapy.
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