Bibliography
- BINDER CJ, CHANG MK, SHAW PX et al.: Innate and acquired immunity in atherogenesis. Nat. Med. (2002) 8(11):1218–1226.
- ••An excellent comprehensive review on the roles of innate and adaptive immunity in atherosclerosis.
- HANSSON GK, LIBBY P, SCHONBECK U, YAN ZQ: Innate and adaptive immunity in the pathogenesis of atherosclerosis. Circ. Res. (2002) 91(4):281–291.
- ••An excellent comprehensive review on the roles of innate and adaptive immunity in atherosclerosis.
- ZHOU X, HANSSON GK: Immunomodulation and vaccination for atherosclerosis. Expert Opin. Biol. Thei: (2004) 4(4):599–612.
- LIBBY P, AIKAWA M: Stabilization of atherosclerotic plaques: New mechanisms and clinical targets. Nat. Med. (2002) 8(11):1257–1262.
- HANSSON GK: Immune mechanisms in atherosclerosis. Arteriosclec Throinb. Vasc. Biol. (2001) 21(12):1876–1890.
- MALLAT Z, BESNARD S, DURIEZ M et al.: Protective role of interleukin-10 in atherosclerosis. Circ. Res. (1999) 85(8):e17–e24.
- PINDERSKI OSLUND HEDRICK CC, OLVERA T et al: Interleukin-10 blocks atherosclerotic events in vitro and in vivo. Arterioscler. Throinb. Vasc. Biol. (1999) 19(12):2847–2853.
- DAUGHERTY A, RATERI DL: T lymphocytes in atherosclerosis: the yin-yang of Thl and Th2 influence on lesion formation. Circ. Res. (2002) 90(10):1039–1040.
- UYEMURA K, DEMER LL, CASTLE SC et al.: Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis. I Clin. Invest. (1996) 97(9):2130–2138.
- VON DER THUSEN JH, KUIPER J, FEKKES ML et al.: Attenuation of atherogenesis by systemic and local adenovirus-mediated gene transfer of interleukin-10 in LDLr-/- mice. FASEB (2001) 15(14):2730–2732.
- PINDERSKI LJ, FISCHBEIN MP, SUBBANAGOUNDER G et al: Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient mice by altering lymphocyte and macrophage phenotypes. Circ Res. (2002) 90(10):1064–1071.
- HUBER SA, SAKKINEN P, DAVID C, NEWELL MK, TRACY RP: T helper-cell phenotype regulates atherosclerosis in mice under conditions of mild hypercholesterolemia. Circulation (2001) 103(21):2610–2616.
- MALLAT Z, HEYMES C, OHAN J et a/.:Expression of interleukin-10 in advanced human atherosclerotic plaques. Relation to inducible nitric oxide synthase expression and cell death. Arteriosclec Throinb. Vasc. Biol. (1999) 19:611–616.
- GRUNIG G, CORRY DB, LEACH MW et al.: Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis. J. Exp. Med. (1997) 185(6):1089–1099.
- COTTREZ F, HURST SD, COFFMAN RL, GROUX H: T regulatory cells 1 inhibit a Th2-specific response in vivo. I Innnunol. (2000) 165 (9):4848–4853.
- HAGENBAUGH A, SHARMA S, DUBINETT SM et al.: Altered immune responses in interleukin-10 transgenic mice. Exp. Med. (1997) 185(12):2101–2110.
- KING VL, SZILVASSY SJ, DAUGHERTY A: Interleukin-4 deficiency decreases atherosclerotic lesion formation in a site-specific manner in female LDL receptor-/- mice. Arterioscler: Thromb. Vase. Biol. (2002) 22(3):456–461.
- DAVENPORT P, TIPPING PG: The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E-deficient mice. Am. J. Pathol. (2003) 163(3):1117–1125.
- SCHONBECK U, SUKHOVA GK, GERDES N, LIBBY P: T (H)2 predominant immune responses prevail in human abdominal aortic aneurysm. Am. J. Pathol. (2002) 161(2):499–506.
- GOJOVA A, BRUN V, ESPOSITO B et al: Specific abrogation of transforming growth factor-{beta} signaling in T cells alters atherosclerotic lesion size and composition in mice. Blood (2003) 102(12):4052–4058.
- ••This paper and [21] show that TGF-I3signalling in T cells controls both Thl and Th2 responses in atherosclerosis, and downregulates the disease process.
- ROBERTSON AK, RUDLING M, ZHOU X et al.: Disruption of TGF-beta signaling in T cells accelerates atherosclerosis. J. Clin. Invest. (2003) 112(9):1342–1350. See [20].
- RONCAROLO MG, BACCHETTA R, BORDIGNON C, NARULA S, LEVINGS MK: Type 1 T regulatory cells. Immunol. Rev (2001) 182:68–79.
- GROUX H: An overview of regulatory T cells. Microbes Infect. (2001) 3(11):883–889.
- MALOY KJ, POWRIE F: Regulatory T cells in the control of immune pathology. Nat. Immunol. (2001) 2(9):816–822.
- ••Excellent review on the role of T reg inimmune-mediated diseases.
- HORI S, NOMURA T, SAKAGUCHI S: Control of regulatory T cell development by the transcription factor Foxp3. Science (2003) 299(5609):1057–1061.
- NAKAMURA K, KITANI A, FUSS I et al:TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice. Immunol (2004) 172(2):834–842.
- MCGUIRK P, MILLS KH: Pathogen-specific regulatory T cells provoke a shift in the Thl/Th2 paradigm in immunity to infectious diseases. Trends Immunol. (2002) 23(9):450–455.
- GROUX H, O& GARRA A, BIGLER M et al.: A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature (1997) 389(6652):737–742.
- WEINER HL: Oral tolerance: immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells. Microbes Infect. (2001) 3(11)947–954.
- GROUX H, FOURNIER N, COTTREZ F: Role of dendritic cells in the generation of regulatory T cells. Semin. Immunol. (2004) 16(2):99–106.
- ••Comprehensive review on the role oftolerogenic dendritic cells.
- APOSTOLOU I, SARUKHAN A, KLEIN L, VON BOEHMER H: Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. (2002) 3(8):756–763.
- ••Excellent review on adaptive T reg.
- CHEN Y, KUCHROO VK, INOBE J, HAFLER DA, WEINER HL: Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science (1994) 265(5176):1237–1240.
- HUYNH ML, FAD OK VA, HENSON PM: Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-betal secretion and the resolution of inflammation. J. Clin. Invest. (2002) 109(1):41–50.
- CHEN W, FRANK ME, JIN W, WAHL SM: TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu. Immunity (2001) 14(6):715–725.
- HUANG FP, PLATT N, WYKES M et al: A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J. Exp. Med. (2000) 191(3):435–444.
- STEINMAN RIVI, TURLEY S, MELLMAN I, INABA K: The induction of tolerance by dendritic cells that have captured apoptotic cells. J. Exp. Med. (2000) 191(3):411–416.
- VERBOVETSKI I, BYCHKOV H, TRAHTEMBERG U et al: Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7. Exp. Med. (2002) 196(12):1553–1561.
- SOHN JH, BORA PS, SUK HJ et al: Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells. Nat. Med. (2003) 9(2):206–212.
- KEMPER C, CHAN AC, GREEN JM et al.: Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature (2003) 421(6921):388–392.
- MARIE JC, ASTIER AL, RIVAILLER P et al.: Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation. Nat. Immunol. (2002) 3(7):659–666.
- MALLAT Z, GOJOVA A, MARCHIOL-FOURNIGAULT C et al: Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice. Circ. Res. (2001) 89(10):930–934.
- LUTGENS E, GIJBELS M, SMOOK M et al.: Transforming growth factor-beta mediates balance between inflammation and fibrosis during plaque progression. Arterioscler: Thromb. Vase. Biol. (2002) 22(6):975–982.
- GRAINGER DJ: Transforming growth factor beta and atherosclerosis: so far, so good for the protective cytokine hypothesis. Arterioscler: Thromb. Vase. Biol. (2004) 24(3):399–404.
- GEISSMANN F, REVY P, REGNAULT A et al.: TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells. Immunol. (1999) 162(8):4567–4575.
- NANDAN D, REINER NE: TGF-beta attenuates the class II transactivator and reveals an accessory pathway of IFN-gamma action. J. Immunol. (1997) 158(3):1095–1101.
- GORELIK L, FLAVELL RA: Abrogation of TGEbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity (2000) 12(2):171–181.
- BUONO C, COME CE, WITZTUM JL et al.: Influence of C3 deficiency on atherosclerosis. Circulation (2002) 105(25):3025–3031.
- PERSSON L, BOREN J, ROBERTSON AK et al.: Lack of complement factor C3, but not factor B, increases hyperlipidemia and atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice. Arteriosclec Thromb. Vase. Biol. (2004)
- HARATS D, YACOV N, GILBURD B, SHOENFELD Y, GEORGE J: Oral tolerance with heat shock protein 65 attenuates Mycobacterium tuberculosis-induced and high-fat-diet-driven atherosclerotic lesions. J. Am. Coll. Cardiol. (2002) 40(7):1333–1338.
- •This study and [50] show that induction of mucosal tolerance limits the development of atherosclerosis.
- MARON R, SUKHOVA G, FARIA AM et al.: Mucosal administration of heat shock protein-65 decreases atherosclerosis and inflammation in aortic arch of low-density lipoprotein receptor-deficient mice. Circulation (2002) 106(13):1708–1715.
- •See [49].
- MALLAT Z, GOJOVA A, BRUN V et al: Induction of a regulatory T cell Type 1 response reduces the development of atherosclerosis in apolipoprotein E-knockout mice. Circulation (2003) 108(10):1232–1237.
- •This work provides evidence for the role of IL-10-producing T reg in atherosclerosis.
- MIZOGUCHI A, MIZOGUCHI E, TAKEDATSU H, BLUMBERG RS, BHAN AK: Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1 d upregulation. Immunity (2002) 16(2):219–230.
- CALIGIURI G, NICOLETTI A, POIRIER B, HANSSON GK: Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice. Clin. Invest. (2002) 109(6):745–753.