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Review

Tumour-targeted chemotherapy with immunoconjugates of calicheamicin

Pages 1445-1452 | Published online: 23 Feb 2005

Bibliography

  • TRAIL P, BIANCHI A: Monoclonalantibody drug conjugates in the treatment of cancer. Carr: Opin. Immunol.! (1999) 11:584–588.
  • DUBOWCHIK G, WALKER M: Receptor-mediated and enzyme-dependent targeting of cytotoxic anti-cancer drugs. Phannacol flier. (1999) 83:67–123.
  • KREITMAN RJ: Immunotoxins in cancer therapy. Carr: Opin. Immunol. (1999) 11(5):577–578.
  • GOLDENBERG DM: Advancing role of radiolabeled antibodies in the therapy of cancer. Cancer Innnunol. Immunother. (2003) 52(5):281–296.
  • MAIESE WM, LECHEVALIER MP, LECHEVALIER HA et al.: Calicheamicins, a novel family of antitumor antibiotics: taxonomy, fermentation and biological properties. J. Antibiotics (1989) 42(4):558–563.
  • THORSON J, SIEVERS E, AHLERT J et al.: Understanding and exploiting nature's chemical arsenal: the past, present and future of calicheamicin research. Curl: Phannaceut. Des. (2000) 6:1841–1879.
  • LEE M, DUNNE T, CHANG C et al.: Calicheamicins, a novel family of antibiotics. Structural elucidations of calicheamicins. J. Ana. Chen]. Soc. (1992) 114:985–987.
  • ZEIN N, SINHA A, MCGAHREN W, ELLESTAD G: Calicheamicin an antitumor antibiotic that cleaves double-stranded DNA site specifically. Science (1988) 240:1198–1201.
  • HINMAN LM, HAMANN PR, WALLACE R et al.: Preparation and characterization of monoclonal antibody conjugates of the calicheamicins: a novel and potent family of antitumor antibiotics. Cancer Res. (1993) 53:3336–3342.
  • HINMAN L, HAMANN P, UPESLACIS J: Preparation of conjugates to monoclonal antibodies. In: Endiyne Antibiotics as Antitumor Agents. Borders D, Doyle T (Eds), Marcel Decker, New York, USA (1995):87–106.
  • HAMANN P, HINMAN L, BEYER C et al.: An anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia. Choice of linker. Bioconjug. Chem. (2002) 13:40–46.
  • HAMANN P, HINMAN L, HOLLANDER I et al.: Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia. Bioconjug. Chem. (2002) 13:47–58.
  • DIJOSEPH J, ARMELLINO D, BOGHAERT E et al.: Antibody-targeted chemotherapy with CMC-544, a CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignancies. Blood (2004) 103: 1807-1814.
  • DIJOSEPH JF, POPPLE WELL A, TICKLE S et al.: Antibody-targeted chemotherapy of B-cell lymphoma using calicheamicin conjugated to murine or humanized antibody against CD22. Cancer Immunol Immunother. (2004) (In Press).
  • BOGHAERT E, SRIDHARAN L, ARMELLINO D et al.: A calicheamicin conjugate that targets Lewis Y selectively destroys Lewis Y-positive human carcinoma cells and xenografts. Gin. Cancer Res. (2004) 10(13):4538–4549.
  • ADAMS GP, SCHIER R, MCCALL AM et al.: High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules. Cancer Res. (2001) 61(12):4750–4755.
  • TENCER J, FRICK I-M, ()QUIST BW, ALM P, RIPPE B: Size selectivity of the glomerular barrier to high molecular weight proteins: upper size limitations of the shunt pathways. Kidney Int. (1998) 53:709–715.
  • BROSS P, BEITZ J, CHEN G et al.: Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia. Clin. Cancer Res. (2001) 7:1490–1496.
  • BERGER M, LEOPOLD L, DOWELL J, KORTH-BRADLEY J, SHERMAN M: Licensure of gemtuzumab ozogamicin for the treatment of selected patients 60 years of age or older with acute myeloid leukemia in first relapse. Invest. New Drugs (2002) 20:395–406.
  • ANDREWS R, SINGER J, BERNSTEIN I: Precursors of colony-forming cells in humans can be distinguished from colony-forming cells by expression of the CD33 and CD34 antigens and light scatter properties. Exp. Med. (1989) 169:1721–1731.
  • SIEVERS E, APPLEBAUM F, SPIELBERGER R et al.: Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: A Phase I study of an anti-CD33 calicheamicin immunoconjugate. Blood (1999) 93:3678–3684.
  • SIEVERS E, LARSON R, STADMAUER E et al.: Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse. Clin. Oncol (2001) 19:3244–3254.
  • LARSON R, BOOGAERTS M, ESTEY E et al.: Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin). Leukemia (2002) 16:1627–1636.
  • SIEVERS E, LARSON R, ESTEY E et al.:Final report of prolonged disease-free survival in patients with acute myeloid leukemia in first relapse treated with gemtuzumab ozogamicin followed by hematopoietic stem cell transplantation. Blood (2002) 100:89a.
  • LINENBERGER M, HONG T, FLOWERS D et al: Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin. Blood (2001) 98:988–994.
  • NAITO K, TAKESHITA A, SHIGENO K et al.: Calicheamicin-conjugated humanized anti-CD33 monoclonal antibody (gemtuzumab zogamicin, CMA-676) shows cytocidal effect on CD33-positive leukemic cell lines but is inactive on P-glycoprotein-expressing sublines. Leukemia (2000) 14:1436–1443.
  • MATSUI H, TAKESHITA A, NAITO K et al.: Reduced effect of gemtuzumab ozogamicin (CMA-676) on P-glycoprotein and/or CD34-positive leukemia cells and its restoration by multidrug resistance modifiers. Leukemia (2002) 16:813–819.
  • WALTER R, LINENBERGER M, HONG T, RADEN W, BERNSTEIN I: Multidrug resistance protein (MRP) attenuates gemtuzumab ozogamicin (GO)-induced cytotoxicity in acute myeloid leukemia (AML). Blood (2003) 100(11):2246–225b.
  • GILES F, KANTARJIAN H, KORNBLAU S et al.: Mylotarg (gemtuzumab ozogamicin) therapy is associated with hepatic venoocclusive disease in patients who have not received stem cell transplantation. Cancer (2001) 92:406–413.
  • NEUMEISTER P, EIBL M, ZINKE-CERWENKA W, SCARPATETTI M, SILL H, LINKESCH W: Hepatic veno-occlusive disease in two patients with relapsed acute myeloid leukemia treated with anti-CD33 calicheamicin (CMA-676) immunoconjugate. Ann. Hematol (2001) 80:119–120.
  • RAJVANSHI P, SHULMAN H, SIEVERS E, MCDONALD G: Hepatic sinusoidal onstruction after gemtuzumab ozogamicin (Mylotarg) therapy. Blood (2002) 99:2310–2314.
  • CHEN A, LUGER S, SICKLES C et al.:Gemtuzumab ozogamicin (IVIylotargTm) therapy for relapsed AML after hematopoetic stem cell transplant: efficacy and incidence of hepatic veno-occlusive disease. Bone Marrow Transplant. (2002) 9:23–28.
  • DOLL C, YARBRO J: Vascular toxicity associated with antineoplastic agents. Semin. Oncol (1992) 19:580–596.
  • RICHARDSON P, GUINAN E: Hepatic veno-occlusive disease following hematopoietic stem cell transplantation. Acta Haematol (2001) 106:57–68.
  • ERBA H, STADTMAUER E, LARSON R et al.: Results of a multivariate analysis to determine factors contributing to the risk of developing hepatic veno-occlusive disease (VOD) following treatment with gemtuzumab ozogamicin. Blood (2002) 100:339a.
  • WADLEIGH M, RICHARDSON PG, ZAHRIEH D et al.: Prior gemtuzumab ozogamicin exposure significantly increases the risk of veno-occlusive disease in patients who undergo myeloablative allogeneic stem cell transplantation. Blood (2003) 102(5):1578–1582.
  • ALVARADO Y, TSIMBERIDOU A, KANTARJIAN H et al.: Pilot study of Mylotarg, idarubicin and cytarabine combination regimen in patients with primary resistant or relapsed acute myeloid 1451 leukemia. Cancer Chemother. Pharmacol (2003) 51:87–90.
  • TSIMERIDOU A, ESTEY E, CORTES J et al: Gemtuzumab, fludarabine, cytarabine, and cyclosporine in patients with newly diagnosed acute myelogenous leukemia or high-risk myelodysplastic syndromes. Cancer (2003) 97(6):1481–1487.
  • BACCARANI M, DURRANT S, LINKESCH W et al.: Preliminary report of a Phase II study of the safety and efficacy of gemtuzumab ozogamicin (Mylotarg) given in combination with cytarabine in patients with acute myeloid leukemia. Blood (2002) 100(11):341a.
  • DE ANGELO D, SCHIFFER C, AMREIN P et al.: Interim analysis of a Phase II study of the safety and efficacy of gemtuzumab ozogamicin (Mylotarg) given in combination with cytarabine and daunorubicin in patients 60 years old with untreated acute myeloid leukemia. Blood (2002) 100(11):198a-199a.
  • ESTEY E, GILES F, BERAN M et al: Experience with gemtuzumab ozogamycin ('mylotarg') and all-trans retinoic acid in untreated acute promyelocytic leukemia. Blood (2002) 99:4222–4224.
  • PETTI M, PINAZZI MB, DIVERIO D et al.: Prolonged molecular remission in advanced acute promyelocytic leukaemia after treatment with gemtuzumab ozogamicin (Mylotarg CMA-676). Br. J. Haematol (2001) 115:63–65.
  • VON MENSDORFF-POUILLY S, SNIJDEWINT FG, VERSTRAETEN AA, VERHEIJEN RH, KENEMANS P: Human MUC1 mucin: a multifaceted glycoprotein. hat. J. Biol. Markers (2000) 15(4):343–356.
  • DAVIES Q, PERKINS AC, FRIER M, WATSON S, LALANI E, SYMONDS EM: The effect of circulating antigen on the biodistribution of the engineered human antibody hCTM01 in a nude mice model. Eur. J. Nucl. Med. (1997) 24(2):206–209.
  • DAVIES Q, PERKINS AC, ROOS JC et al.: An immunoscintigraphic evaluation of the engineered human monoclonal antibody (hCTM01) for use in the treatment of ovarian carcinoma. Br. Obstet. Cynaecol (1999) 106(1):31–37.
  • VAN HOF AC, MOLTHOFF CE DAVIES Q: Biodistribution of (111)indium-labeled engineered human antibody CTMO1 in ovarian cancer patients: influence of protein dose. Cancer Res. (1996) 56(22):5179–5185.
  • GILLESPIE AM, BROADHEAD TJ, CHAN SY et al.: Phase I open study of the effects of ascending doses of the cytotoxic immunoconjugate CMB-401 (hCTM01-calicheamicin) in patients with epithelial ovarian cancer. Ann. Oncol (2000) 11(6):735–741.
  • CHAN SY, GORDON AN, COLEMAN RE et al.: A Phase II study of the cytotoxic immunoconjugate CMB-401 (hCTM01-calicheamicin) in patients with platinum-sensitive recurrent epithelial ovarian carcinoma. Cancer Immunol Immunother. (2003) 52(4):243–248.
  • CROCKER PR, VARKI A: Siglecs, sialic acis, and innate immunity. Trends Immunol (2001) 22:337–342.
  • LI JL, SHEN GL, GHETIE MA et al.: The epitope specificity and tissue reactivity of four murine monoclonal anti-CD22 antibodies. Cell. Immunol (1989) 118:85–99.
  • HANNA R, ONG G, MATTES M: Processing of antibodies bound to B-cell lymphomas and other hematological malignancies. Cancer Res. (1996) 56:3062–3068.
  • DIJOSEPH JF, GOAD ME, DOUGHER MM et al: Potent and specific antitumour efficacy of CMC-544, a CD22-targeted immunoconjugate of calicheamicin, against systemically disseminated B-cell lymphoma. Clin. Cancer Res. (2004) (In Press). Websites
  • http://www.bexxar.com Information on Bexxar.
  • http://www.zevalin.com Information on Zevalin.
  • http://www.ligand.com/pdf/ONTAKPI.pdf Information on ONTAK.

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