141
Views
9
CrossRef citations to date
0
Altmetric
Review

Polycation-mediated delivery of siRNAs for prophylaxis and treatment of influenza virus infection

, , , &
Pages 495-505 | Published online: 22 Apr 2005

Bibliography

  • CHUAH MK, COLLEN D VANDENDRIESSCHE T: Gene therapy for hemophilia. J. Gene Med. (2001) 3(1):3–20.
  • MONTIER T, DELEPINE P, PICHON C, FEREC C, PORTEOUS DJ, MIDOUX P: Non-viral vectors in cystic fibrosis gene therapy: progress and challenges. Trends Biotech. (2004) 22(11):586–592.
  • IZQUIERDO M: Short interfering RNAs as a tool for cancer gene therapy Cancer Gene Ther. (2004) 12(3):217–227.
  • ANDERSON DG, PENG W, AKINC A et al.: A polymer library approach to suicide gene therapy for cancer Proc. Nail. Acad. Sci. USA (2004) 101(45):16028–16033.
  • QUARCK R, HOLVOET P: Gene therapy approaches for cardiovascular diseases. Curr. Gene Ther. (2004) 4(2):207–223.
  • LOWENSTEIN PR, CASTRO MG: Recent advances in the pharmacology of neurological gene therapy. Curr. Opin. Pharmacol (2004) 4(1):91–97.
  • FANNING G, AIVIADO R, SYMONDS G: Gene therapy for HIV/AIDS: the potential for a new therapeutic regimen./ Gene Med. (2003) 5(8):645–653.
  • PENG Z, XIAO Z, WANG Yet al.: Reversal of P-glycoprotein-mediated multidrug resistance with small interference RNA (siRNA) in leukemia cells. Cancer Gene Ther. (2004) 11(11):707–712.
  • KURRECK J: Antisense technologies. Improvement through novel chemical modifications. Eur. j Biochem. (2003) 270(8):1628–1644. A good review on antisense strategies.
  • SCANLON KJ: Anti-genes: siRNA, ribozymes and antisense Curr. Pharm. Biotechnol. (2004) 5(5):415–420.
  • FIRE A:. XU S, MONTGOMERY MK, KOSTAS SA, DRIVER SE, MELLO CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 391(6669):806–811.
  • •The first paper to describe RNAi.
  • ELBASHIR SM, HARBORTH J, LENDECKEL W, YALCIN A, WEBER K, TUSCHL T: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (2001) 411(6836):494–498.
  • ••The first paper to describe siRNA-mediatedgene silencing in mammalian cells.
  • MCMANUS MT, SHARP Pk Gene silencing in mammals by small interfering RNAs. Nat. Rev. Gen. (2002) 3(10:737–747.
  • THOMAS M, KLIBANOV AM: Non-viral gene therapy: polycation-mediated DNA delivery. Appl Microbiol Biotechnol (2003) 62(1):27–34.
  • REID AH, FANNING TG, JANCZEWSKI TA, TAUBENBERGER JK: Characterization of the 1918 'Spanish' influenza virus neuraminidase gene. Proc. Natl. Acad. Sci. USA (2000) 97(12):6785–6790.
  • WOOD JM, ROBERTSON JS: From lethal virus to life-saving vaccine: developing inactivated vaccines for pandemic influenza. Nat. Rev. Microbiol (2004) 2(10):842–847.
  • GOVAERT TM, THUS CT, MASUREL N, SPRENGER MJ, DINANT GJ, KNOTTNERUS JA: The efficacy of influenza vaccination in elderly individuals. A randomized double-blind placebo-controlled trial. JAMA (1994) 272(21):1661–1665.
  • MAEDA T, SHINTANI Y, NAKANO K, TERASHIMA K, YAMADA Y: Failure of inactivated influenza A vaccine to protect healthy children aged 6-24 months. Pediatr. Int. (2004) 46(2):122–125.
  • RUBEN FL: Inactivated influenza virus vaccines in children. Clin. Infra. Dis. (2004) 38(5):678–688.
  • MONTO AS: The role of antivirals in the control of influenza. Vaccine (2003) 21(16):1796–1800.
  • KISO M, MITAMURA K, SAKAI-TAGAWA Yet al: Resistant influenza A viruses in children treated with oseltamivir: descriptive study. Lancet (2004) 364(9430:759–765.
  • GE Q, MCMANUS MT, NGUYEN T et al.: RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc. Natl Acad. Sci. USA (2003) 100(5):2718–2723.
  • GE Q, FILIP L, BAI A, NGUYEN T, EISEN HN, CHEN J: Inhibition of influenza virus production in virus-infected mice by RNA interference. Proc. Nail Acad. Sci. USA (2004) 101(23):8676–8681.
  • ••The first report on the in vivo inhibition ofinfluenza infection by polycation-mediated siRNA delivery.
  • KAISER J: Influenza: girding for disaster. Searching for all-powerful flu weapons. Science (2004) 306(5695):395.
  • NAYAK DP, HUT EK, BARMAN S: Assembly and budding of influenza virus. Virus Res. (2004) 106(2):147–165.
  • HAY, STEVENS DJ, SKEHEL JJ, WILEY DC: H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes. EMBO J. (2002) 21(5):865–875.
  • WEBBY RJ, ROSSOW K, ERICKSON G, SIMS Y, WEBSTER R: Multiple lineages of antigenically and genetically diverse influenza A virus co-circulate in the United States swine population. Virus Res. (2004) 103(1-2):67–73.
  • KOBASA D, TAKADA A, SHINYA K et al.: Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus. Nature (2004) 431(7009):703–707.
  • SUZUKI H, SAITO R, MASUDA H, OSHITANI H, SATO M, SATO I: Emergence of amantadine-resistant influenza A viruses: epidemiological study. J. Infect. Chemother. (2003) 9(3):195–200.
  • SAITO R, SAKAI T, SATO I et ill.: Frequency of amantadine-resistant influenza A viruses during two seasons featuring cocirculation of H1N1 and H3N2. J. Clin. Microbiol (2003) 41(5):2164–2165.
  • GUBAREVA LV, KAISER L, HAYDEN FG: Influenza virus neuraminidase inhibitors. Lancet (2000) 355(9206):827–835.
  • STEINDL T, LANGER T: Influenza virus neuraminidase inhibitors: generation and comparison of structure-based and common feature pharmacophore hypotheses and their application in virtual screening. J. Chem. Inf Comput. Sci. (2004) 44(5):1849–1856.
  • BELSHE RB, NICHOL KL, BLACK SB et al.: Safety, efficacy, and effectiveness of live, attenuated, cold-adapted influenza vaccine in an indicated population aged 5-49 years. Clin. Infect. Dis. (2004) 39(7):920–927.
  • DYER O: Shortage of flu vaccine in US sparks political row. Br. Med. J. (2004) 329(7473):998.
  • MAMMEN M, CHOI SK, WHITESIDES JM: Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors. Angew. Chem. Int. Edn. (1998) 37(20):2754–2794.
  • REUTER JD, MYC A, HAYES MM et al: Inhibition of viral adhesion and infection by sialic-acid-conjugated dendritic polymers. Bioconjug. Chem. (1999) 10(2):271–278.
  • SPEVAK W, NAGY JO, CHARYCH DH, SCHAEFER ME, GIIBERT JH, BEDNARSKI MD: Polymerized liposomes containing C-glycosides of sialic acid: potent inhibitors influenza virus in vitro infectivity. J. Am. Chem. Soc. (1993) 115(3):1146–1147.
  • TOTANI K, KUBOTA T, KURODA T et al.: Chemoenzymatic synthesis and application of glycopolymers containing multivalent sialyloligosaccharides with a poly(L-glutamic acid) backbone for inhibition of infection by influenza viruses. Glycobiology (2003) 13(5):315–326.
  • LANDERS JJ, CAO Z, LEE I et al: Prevention of influenza pneumonitis by sialic acid-conjugated dendritic polymers. J. Infect. Dis. (2002) 186(9):1222–1230.
  • GAMBARYAN AS, TUZIKOV AB, CHINAREV AA, JUNEJA LR, BOVIN NV, MATROSOVICH MN: Polymeric inhibitor of influenza virus attachment protects mice from experimental influenza infection. Antiviral Res. (2002) 55(1) :201–205.
  • GITLIN L, KARELSKY S, ANDINO R: Short interfering RNA confers intracellular antiviral immunity in human cells. Nature (2002) 418(6896):430–434.
  • NOVINA CD, MURRAY MF, DYKXHOORN DM et al.: siRNA-directed inhibition of HIV-1 infection. Nat. Med. (2002) 8(7):681–686.
  • HAN W, WIND-ROTOLO M, KIRKMAN RL, MORROW CD: Inhibition of human immunodeficiency virus type 1 replication by siRNA targeted to the highly conserved primer binding site. Virology (2004) 330(1):221–232.
  • YOKOTA T, SAKAMOTO N, ENOMOTO N et al.: Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs. EMBO Rep. (2003) 4(6):602–608.
  • LU A, ZHANG H, ZHANG X et ill.: Attenuation of SARS coronavirus by a short hairpin RNA expression plasmid targeting RNA-dependent RNA polymerase. Virology (2004) 324(1):84–89.
  • ZHENG BJ, GUAN Y, TANG Q et al: Prophylactic and therapeutic effects of small interfering RNA targeting SARS-coronavirus. Antivir. Ther. (2004) 9(3):365–374.
  • GILADI H, KETZINEL-GILAD M, RIVKIN L, FELIG Y, NUSSBAUM O, GALUN E: Small interfering RNA inhibits hepatitis B virus replication in mice. MoL Ther. (2003) 8(5):769–776.
  • MCCAFFREY AP, NAKAI H, PANDEY K et al.: Inhibition of hepatitis B virus in mice by RNA interference. Nat. Biotechnol (2003) 21(6):639–644.
  • CHEN W, YAN W, DU Q et ill.: RNA interference targeting VP1 inhibits foot-and-mouth disease virus replication in BHK-21 cells and suckling mice. J. Virol (2004) 78(13):6900–6907.
  • ROSENECKER J, NAUNDORF S, GERSTING SW et al.: Interaction of bronchoalveolar lavage fluid with polyplexes and lipoplexes: analysing the role of proteins and glycoproteins. J. Gene Med. (2003) 5(1):49–60.
  • ERNST N, ULRICHSKOTTER S, SCHMALIX WA et al.: Interaction of liposomal and polycationic transfection complexes with pulmonary surfactant. J. Gene Med. (1999) 1(5):331–340.
  • RUDOLPH C, LAUSIER J, NAUNDORF S, MULLER RH, ROSENECKER J: In vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers. J. Gene Med. (2000) 2(4):269–278.
  • KABANOV AV: Taking polycation gene delivery systems from in vitro to in vivo. Pharm. Sci. Technol. Today (1999) 2(9):365–372.
  • MARSHALL E: Gene therapy death prompts review of adenovirus vector. Science (1999) 286(5448):2244–2245.
  • HACEIN-BEY-ABINA S, VON KALLE C, SCHMIDT M et al.: LM02-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science (2003) 302(5644):415–419.
  • BOYCE N: Trial halted after gene shows up in semen. Nature (2001) 414(6865):677.
  • BELTING M: Heparan sulfate proteoglycan as a plasma membrane carrier. Trends Biochem. Sci. (2003) 28(3):145–151.
  • ZUHORN IS, OBERLE V, VISSER WH et al.: Phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency. Biophys. J. (2002) 83(4):2096–2108.
  • BOUSSIF O, LEZOUALC'H F, ZANTA MA et al.: A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc. Natl Acad. Sci. USA (1995) 92 (16): 7297–72301.
  • THOMAS M, KLIBANOV AM: Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells. Proc. Natl Acad. Sci. USA (2002) 99(23):14640–14645.
  • AKINC A, THOMAS M, KLIBANOVAM, LANGER R: Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis. J.Gene Med. (2004) (In Press).
  • SONAWANE ND, SZOKA FC JR, VERKMAN AS: Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J. Biol. Chem. (2003) 278(45):44826–44831.
  • THOMAS M, GE Q, LU JJ, CHEN J, KLIBANOV AM: Cross-linked small polyethylenimines: while still non-toxic, deliver DNA efficiently to mammalian cells in vitro and in vivo. Pharm. Res. (2005) (In Press).
  • CHOOSAKOONKRIANG S, LOBO BA, KOE GS, KOE JG, MIDDAUGH CR: Biophysical characterization of PEI/DNA complexes. J. Pharm. Sci. (2003) 92(8):1710–1722.
  • WIGHTMAN L, KIRCHEIS R, ROSSLER Vet al.: Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo. J. Gene Med. (2001) 3(4):362–372.
  • ZOU SM, ERBACHER P, REMY JS, BEHR JP: Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse./ Gene Med. (2000) 2(2):128–134.
  • TOMPKINS SM, LO CY, TUMPEY TM, EPSTEIN SL: Protection against lethal influenza virus challenge by RNA interference in vivo. Proc. Nail. Acad. Sci. USA (2004) 101(23):8682–8686.
  • ••Reports the in vivo inhibition of influenza infection by hydrodynamic transfection of siRNA.
  • THOMAS M, LU JJ, GE Q, ZHENG C, CHEN J, KLIBANOV AM: Full deacylation of polyethylenimine dramatically enhances its gene delivery efficiency and specificity to mouse lung. Proc. Natl Acad. Sci. USA (2005) (In Press).

Websites

  • http://www.cdc.gov/flu CDC influenza information page.
  • http://www.who.int/vaccines/en/ influenza.shtml WHO influenza vaccine page.
  • http://www.wiley.co.uk/genmeci/clinical/ The Journal of Gene Medicine clinical trial website.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.