Bibliography
- BENTLEY AM, JACOBSON MR, CUMBERWORTH V BARKANS JR, MOQBEL R, SCHWARTZ LB: Immunohistology of the nasal mucosa in seasonal allergic rhinitis: increases in activated eosinophils and epithelial mast cells. J. Allergy Clin. Immunol. (1992) 89:877–883.
- BOUSQUET J, LOCKEY RF, MALLING HJ: WHO position paper. Allergen immunotherapy: therapeutic vaccines for allergic diseases. Allergy (1998) 53:S1–S42.
- MOLLER UR, MOSBECH H: Position paper: immunotherapy with hymenoptera venoms. Allergy (1993) 48:36–46.
- DURHAM SR, WALKER SM, VARGA E-V et al.: Long-term clinical efficacy of grass-pollen immunotherapy. N Engl. J. Med. (1999) 341:468–475.
- VAN NEERVEN RJJ, WIKBORG T, LUNDG et al.: Blocking antibodies induced by specific allergy vaccination prevent the activation of CD4+ T cells by inhibiting serum IgE-facilitated allergen presentation. J. Immunol. (1999) 163:2944–2952.
- ROCKLIN RE, SHEFFER A, GREINEDER DK, MELMON KL: Generation of antigen-specific suppressor cells during allergy desensitization. N EngL J. Med. (1980) 302:1213–1219.
- CRETICOS PS, ADKINSON NF JR., KAGEY-SOBOTKAA et al: Nasal challenge with ragweed pollen in hay fever patients. Effect of immunotherapy. j Clin. Invest. (1985) 76:2247–2253.
- RAK S, LOWHAGEN O, VENGE P: The effect of immunotherapy on bronchial hyperresponsiveness and eosinophil cationic protein in pollen-allergic patients. J. Allergy Clin. Immunol. (1988) 82:470–480.
- AKDIS CA, AKDIS M, BLESKEN T et al.: Epitope specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro. J. Clin. Invest. (1996) 98:1676–1683.
- AKDIS CA, BLESKEN T, AKDIS M, WIDTHRICH B, BLASER K: Role of IL-10 in specific immunotherapy. j Clin. Invest. (1998) 102:98–106.
- JUTEL M, AKDIS M, BUDAK F et al.: IL-10 and TGF-13 cooperate in regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur. j Immunol. (2003) 33:1205–1214.
- AKDIS M, VERHAGEN J, TAYLOR A et al.: Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J. Exp. Med. (2004) 199:1567–1575.
- AKDIS CA, BLASER K, AKDIS M: Genes of tolerance. Allergy (2004) 59:897–913.
- JUTEL M, WATANABE T, KLUNKER S et al.: Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors. Nature (2001) 413:420–425.
- AKDIS CA, BLASER K: Bypassing IgE andtargeting T cells for specific immunotherapy of allergy. Trends Immunol. (2001) 22:175–178.
- AKDIS CA, BLESKEN T, WYMANN D, AKDIS M, BLASER K: Differential regulation of human T cell cytokine patterns and IgE and IgG4 responses by conformational antigen variants. Eur. Immunol. (1998) 28:914–925.
- MOLLER UR, AKDIS CA, FRICKER M et al.: Successful immunotherapy with T cell epitope peptides of bee venom phospholipase A2 induces specific T cell anergy in bee sting allergic patients. J. Allergy Clinimmunol. (1998) 101:747–754.
- MARCOTTE GV, BRAUN CM, NORMAN PS et al.: Effects of peptide therapy on ex vivo T-cell responses. J. Allergy Clin. Immunol. (1998) 101:506–513.
- OLDFIELD WL, LARCHE M, KAY AB: Effect of T-cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: a randomised controlled trial. Lancet (2002) 360:47–53.
- KUSSEBI F, KARAMLOO F, RHYNER C et al.: A major allergen gene-fusion protein for potential usage in allergen-specific immunotherapy. J. Allergy Clin. Immunol. (2005) (In press).
- KARAMLOO F, SCHMID-GRENDELMEIER P, KUSSEBI F et al.: Recombinant multiallergen vaccine for specific immunotherapy with reduced IgE binding and preserved T cell epitopes. Eur. J. Immunol. (2005).
- NIEDERBERGER V, HORAK F, VRTALA S et al.: Vaccination with genetically engineered allergens prevents progression of allergic disease. Proc. Nail Acad. Sci. USA (2004) 101(Suppl. 2):14677–14682.
- AKDIS CA, KUSSEBI F, PULENDRAN B et al.: Inhibition of T helper 2-type responses, IgE production and eosinophilia by synthetic lipopeptides. Eur. j Immunol. (2003) 33:2717–2726.
- SIMONS FE, SHIKISHIMA Y, VAN NEST G, EIDEN JJ, HAYGLASS KT: Selective immune redirection in humans with ragweed allergy by injecting Amb a 1 linked to immunostimulatory DNA. J. Allergy Clin. Immunol. (2004) 113:1144–1151.