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Review

Transgenic plants in the biopharmaceutical market

, &
Pages 185-218 | Published online: 22 Apr 2005

Bibliography

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  • •In this report, the co-expression of a mammalian glactosyltransferase allows plants to produce recombinant antibodies with galactose residues on their glycan chains. The proportion of antibodies bearing the galactose residues was similar to that seen in mammalian expression systems.
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  • ••An exciting report showing that gene targeting strategies can be used to eliminate the enzymes responsible for adding nonmammalian carbohydrate residues to the glycans of recombinant glycoproteins produced in plants.
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