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Review

Drugs for male contraception

Pages 291-308 | Published online: 24 Feb 2005

Bibliography

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  • ••A review with many useful references.
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  • •A review of the fundamentals of spermatogenesis.
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  • ••Assesses the needs of the field.
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  • •An interesting analysis of contraception.
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  • •Discusses this particular approach of contraception.
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  • •A review which discusses this complex situation.
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  • •This paper discusses an interesting approach to delivery of drugs.
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  • •An interesting article which describes a particular approach to male contraception.
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  • •A medicinal chemistry approach to the development of male contraceptives.
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  • HILD-PETITO S, REEL JR, LARNER JM, BLYE RP: Mechanism of action of a male antifertil-ity drug, CDB 4022 ([4aRS,5SR,9bRS]-2-ethy1-2,3,4,4a,5,9b-hexahydro-8-iodo-7-methy1-514-carbomethoxyphenyl]-1H-indeno(1,2-c)pyridine hydrochloride). Biol. Reprod. (1998) 58(Suppl.):169.
  • HILD-PETITO S, MEISTRICH ML, REEL JR, BLYE RP: Protective effect of lupron depot on spermatogenesis and fertility in male rats treated orally with a potent indenopyridine (CDB 4022; [4aRS,5SR,9f3RS]-2-ethy1-7-methy1-2,3,4,4a,5,913-hexahydro-544-carbomethoxyphenyl]-1H-indeno[1,2-dpyridine-hydroiodide) {sic, The correct name is [4aRS,5SR,9bRS] -2-Ethy1-7-methy1-2,3,4,4a,5,9b-hexahydro-5-(4-carbomethoxyphenyl) -8--iodo-1H-indeno [1,2-c] pyridine (RTI-4587-073 or CDB 4022)1. XIVth Testis Workshop (1997) [Abstract].
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  • •This paper describes the mechanism of action of these potential contraceptives.
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  • •A good discussion of practical development needs.
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  • BONN D: Male contraceptive research steps back into spotlight. Lancet (1999) 353:302.

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