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Review

Prospects and problems of gene therapy: an update

Pages 187-198 | Published online: 25 Feb 2005

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  • ••Interesting approach to cancer genetherapy.
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  • ••Interesting gene therapy approach utilisingintrinsic herpes virus properties.
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  • ••Paper describing characterisation of SIS ina number of genes present in commonly used plasmids.
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  • MCINERNEY JM, NAWROCKI JR, LOWREY CH: Long-term silencing of retroviral vectors is resistant to reversal by trichostatin A and 5-azacytidine. Gene Ther.(2000) 7:653–663.
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  • ••Transplanted adult bone marrow cellsmigrated into the brain and differentiated into cells that expressed neurone-specific antigens.
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  • ••Identification and isolation ofhaematopoietic stem cells.

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