Bibliography
- US RENAL DATA SYSTEM: USRDS 2003 Annual Data Report: atlas of end-stage renal disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA (2003).
- BILLINGHAM RE, BRENT L, MEDAWAR PB: Activity acquired tolerance of foreign cells. Nature (1953) 172 (4379) :603–606.
- ••Landmark paper describing tolerance.
- KOHLER G, MILSTEIN C: Continuous cultures of fused cells secreting antibody of predefined specificity. Nature (1975) 256(5517):495–497.
- ••Landmark paper on the discovery ofmonoclonal antibodies.
- STARZL TE, MARCHIORO TL, WADDELL WR: The reversal of rejection in human renal homografts with subsequent development of homograft tolerance. Surg. Gynecol Obstet. (1963) 117:385–395.
- •Early paper using glucocorticoid immunosuppression in kidney transplantation.
- TANPHAICHITR NT, BRENNAN DC: Infectious complications in renal transplant recipients. Adv. Ren. Replace. The]: (2000) 7(2):131–146.
- PENN I: Cancers in renal transplant recipients. Adv. Ren. Replace. The]: (2000) 7(2):147–156.
- SCHWENGER V, ZEIER M, RITZ E: Hypertension after renal transplantation. Ann. Transplant. (2001) 6(4):25–30.
- PANNU HS, SINGH D, SANDHU JS: Lipid profile before and after renal transplantation-a longitudinal study. Ren. Fail (2003) 25(3):411–417.
- SPRAGUE SM, JOSEPHSON MA: Bone disease after kidney transplantation. Semin. Nephrol (2004) 24(1):82–90.
- PILMORE HL, DITTMER ID: Calcineurin inhibitor nephrotoxicity: reduction in dose results in marked improvement in renal function in patients with coexisting chronic allograft nephropathy. Clin. Transplant. (2002) 16(3):191–195.
- NANKIVELL BJ, BORROWS RJ, FUNG CL, O'CONNELL PJ, ALLEN RD, CHAPMAN JR: The natural history of chronic allograft nephropathy. N Engl. J. Med. (2003) 349(24):2326–2333.
- LAFFERTY KJ, CUNNINGHAM AJ: A new analysis of allogeneic interactions. Aust. I Exp. Biol. Med. Sci. (1975) 53(1):27–42.
- MATZINGER P: Tolerance, danger, andthe extended family. Ann. Rev Immunol 12:991–1045.
- SCHROFF RW, FOON KA, BEATTY SM, OLDHAM RK, MORGAN AC JR: Human anti-murine immunoglobulin responses in patients receiving monoclonal antibody therapy. Cancer Res. (1985) 45(2):879–885.
- SHAWLER DL, BARTHOLOMEW RM, SMITH LM, DILLMAN RO: Human immune response to multiple injections of murine monoclonal IgG. Immunol (1985) 135(2):1530–1535.
- BOULIANNE GL, HOZUMI N, SHULMAN MJ: Production of functional chimaeric mouse/human antibody. Nature (1984) 312(5995):643–646.
- •Seminal paper on chimaeric antibody engineering.
- MORRISON SL, JOHNSON MJ, HERZENBERG LA, OI VT: Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains. Proc. Natl Acad. Sci. USA (1984) 81(21):6851–6855.
- •Seminal paper on chimaeric antibody engineering.
- REICHMANN L, CLARK M, WALDMANN H, WINTER G: Reshaping human antibodies for therapy. Nature (1988) 332(6162):323–327.
- •Seminal paper on humanised antibody engineering.
- JONES PT, DEAR PH, FOOTE J, NEUBERGER MS, WINTER G: Replacing the complementarity-determining regions in a human antibody with those from a mouse. Nature (1986) 321(6069):522–525.
- •Seminal paper on humanised antibody engineering.
- MENDEZ MJ, GREEN LL, CORVALAN JR et al.: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice. Nat. Genet. (1997) 15(2):146–156.
- LEDBETTER JA, JUNE CH, MARTIN PJ, SPOONER CE, HANSEN JA, METER KE: Valency of CD3 binding and internalization of the CD3 cell-surface complex control T cell responses to second signals: distinction between effects on protein kinase C, cytoplasmic free calcium, and proliferation. ./. Immunol (1986) 136(10:3945–3952.
- MARANO N, HOLOWKA D, BAIRD B: Bivalent binding of an anti-CD3 antibody to Jurkat cells induces association of the T cell receptor complex with the cytoskeleton. ./. Immunol (1989) 143(3):931–938.
- TODD PA, BROGDEN RN: Muromonab CD3. A review of its pharmacology and therapeutic potential. Drugs (1989) 37(6):871–899.
- GONCALVES LF, RAUBER ML, MANFRO RC, PROMPT CA: Fine needle aspiration biopsy in renal transplant patients on prophylactic OKT3 treatment. Transplant. Proc. (1992) 24(6):3085–3086.
- WONG JT, EYLATH AA, GHOBRIAL I, COLVIN RB: The mechanism of anti-CD3 monoclonal antibodies. Mediation of cytolysis by inter-T cell bridging. Transplantation (1990) 50(4):683–689.
- NORMAN DJ: Mechanisms of action and overview of OKT3. Ther. Drug Monit. (1995) 17(6): 615–620.
- ORTHO MULTICENTER TRANSPLANT STUDY GROUP: A randomized clinical trial of OKT3 monoclonal antibody for acute rejection of cadaveric renal transplants. N Engl. I Med. (1985) 313(6):337–342.
- ••Landmark trial leading to first FDAapproval of a monoclonal antibody.
- ABRAMOWICZ D, SCHANDENE L, GOLDMAN M et al: Release of tumor necrosis factor, interleukin-2, and gamma-interferon in serum after injection of OKT3 monoclonal antibody in kidney transplant recipients. Transplantation (1989) 47(4):606–608.
- CHATENOUD L, FERRAN C, LEGENDRE C et al: In vivo cell activation following OKT3 administration. Systemic cytokine release and modulation by corticosteroids. Transplantation (1990) 49(4):697–702.
- COSTANZO-NORDIN MR: Cardiopulmonary effects of OKT3: determinants of hypotension, pulmonary edema, and cardiac dysfunction. Transplant. Proc. (1993) 25(2 Suppl. 1):21–24.
- GOLDSTEIN G, FUCCELLO AJ, NORMAN DJ, SHIELD CF 3rd, COLVIN RB, COSIMI AB: OKT3 monoclonal antibody plasma levels during therapy and the subsequent development of host antibodies to OKT3. Transplantation (1986) 42(5):507–511.
- ALEGRE ML, PETERSON LJ, XU D et al.: A non-activating 'humanized' anti-CD3 monoclonal antibody retains immunosuppressive properties in vivo. Transplantation (1994) 57(11):1537–1543.
- WOODLE ES, XU D, ZIVIN RA et al: Phase I trial of a humanized, Fc receptor nonbinding OKT3 antibody, huOKT3gammal (Ala-Ala) in the treatment of acute renal allograft rejection. Transplantation (1999) 68(5):608–616.
- PARLEVLIET KJ, TEN BERGE IJ, YONG SL et al.: In vivo effects of IgA and IgG2a anti-CD3 isotype switch variants. Clin. Invest. (1994) 93(6):2519–2525.
- MEIJER RT, SURACHNO S, YONG SL et al.: Treatment of acute kidney allograft rejection with a non-mitogenic CD3 antibody. Clin. Exp. Immunol (2003) 133(3):485–492.
- HENRY ML, PELLETIER RP, ELKHAMMAS EA, BUMGARDNER GL, DAVIES EA, FERGUSON RM: A randomized prospective trial of OKT3 induction in the current immunosuppression era. Clin. Transplant. (2001) 15(6):410–414.
- FLECHNER SM, GOLDFARB DA, FAIRCHILD R et al.: A randomized prospective trial of low-dose OKT3 induction therapy to prevent rejection and minimize side effects in recipients of kidney transplants. Transplantation (2000) 69(11):2374–2381.
- OH HK, PROVENZANO R, TAYEB J, SATMARY N, JONES B: Two low-dose OKT3 induction regimens following renal transplantation-clinical experience at a single center. arr. Transplant (1998) 12(4):343–347.
- HALE G, WALDMANN H: CAMPATH-1 monoclonal antibodies in bone marrow transplantation. Hematother (1994) 3(1):15–31.
- HALE G, SLAVIN S, GOLDMAN JM, MACKINNON S, GIRALT S, WALDMANN H: Alemtuzumab (Campath-1H) for treatment of lymphoid malignancies in the age of nonmyeloablative conditioning? Bone Marrow Transplant. (2002) 30(12):797–804.
- HALE G, BRIGHT S, CHUMBLEY G et al.: Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement. Blood (1983) 62 (4) : 873–882.
- FRIEND PJ, HALE G, WALDMANN H et al: Campath-1M-prophylactic use after kidney transplantation. A randomized controlled clinical trial. Transplantation (1989) 48(2):248–253.
- FRIEND PJ, WALDMANN H, HALE G et al.: Reversal of allograft rejection using the monoclonal antibody, Campath-1G. Transplant. Proc. (1991) 23(4): 2253–2254.
- KNECHTLE SJ, VARGO D, FECHNER J et al: FN18-CRM9 immunotoxin promotes tolerance in primate renal allografts. Transplantation (1997) 63(1):1–6.
- THOMAS JM, NEVILLE DM, CONTRERAS JL et al: Preclinical studies of allograft tolerance in rhesus monkeys: a novel anti-CD3-immunotoxin given peritransplant with donor bone marrow induces operational tolerance to kidney allografts. Transplantation (1997) 64(1):124–135.
- CALNE R, FRIEND P, MOFFATT S et al: Prope tolerance, perioperative campath 1H, and low-dose cyclosporin monotherapy in renal allograft recipients. Lancet (1998) 351(9117):1701–1702.
- ••The first trial using alemtuzumab intransplantation and introducing the concept that depletional therapy can Induce prope tolerance.
- CALNE R, MOFFATT SD, FRIEND PJ et al.: Campath IH allows low-dose cyclosporine monotherapy in 31 cadaveric renal allograft recipients. Transplantation (1999) 68(10):1613–1616.
- KNECHTLE SJ, PIRSCH JD, H FECHNER J, JR et al: Campath-1H induction plus rapamycin monotherapy for renal transplantation: results of a pilot study. Am. I Transplant. (2003) 3(6):722–730.
- LEVENTHAL JR, GALLON L, KAUFMAN DB et al: Alemtuzumab (Campath 1-H) facilitates prednisone-free immunosuppression (IP) in kidney transplant recipients. Am. J. Transplant. (2003) 3\(Suppl. 5):310.
- KIRK AD, HALE DA, MANNON RB et al.: Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (Campath-1H). Transplantation (2003) 76(1):120–129.
- ••The only trial to investigate the isolatedeffects of depletion in man.
- WU Z, BENSINGER SJ, ZHANG J et al: Homeostatic proliferation is a barrier to transplantation tolerance. Nat. Med. (2004) 10(1):87–92.
- DUSTIN ML, SANDERS ME, SHAW S, SPRINGER TA: Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion. Exp. Med. (1987) 165(3):677–692.
- SAMELSON LE, FLETCHER MC, LEDBETTER JA, JUNE CH: Activation of tyrosine phosphorylation in human T cells via the CD2 pathway. Regulation by the CD45 tyrosine phosphatase. Immunol (1990) 145(8):2448–2454.
- NIZET Y, CHENTOUFI AA, DE LA PARRA B et al: The experimental (in vitro) and clinical (in vivo) immunosuppressive effects of a rat IgG2b anti-human CD2 mAb, LO-CD2a/BTI-322. Transplantation (2000) 69(7):1420–1428.
- BESSE T, MALAISE J, MOURAD M et al: Prevention of rejection with BTI-322 after renal transplantation (results at 9 months). Transplant. Proc. (1997) 29(5):2425–2426.
- SPITZER TR, MCAFEE SL, DEY BR et al.: Nonmyeloablative haploidentical stem-cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies. Transplantation (2003) 75(10):1748–1751.
- THOMAS ML: The leukocyte common antigen family. Ann. Rev Immunol (1989) 7:339–369.
- LYNCH KW, WEISS A: A model systemfor activation-induced alternative splicing of CD45 pre-mRNA in T cells implicates protein kinase C and Ras. Mol Cell. Biol. (2000) 20(1):70–80.
- BINDON CI, HALE G, CLARK M, WALDMANN H: Therapeutic potential of monoclonal antibodies to the leukocyte-common antigen. Synergy and interference in complement-mediated lysis. Transplantation (1985) 40(5):538–544.
- CAMERON MJ, XU L, LONGSI R et al: Identification of gene expression profiles that correlate with tolerance induced by anti-CD45RB MAB treatment in a non-human-primate kidney allograft model. Am. I Transplant. (2003) 3 (Suppl. 5):263.
- TANIGUCHI T, MINAMI Y: The IL-2/ IL-2 receptor system: a current overview. Cell. (1993) 73(1):5–8.
- GOEBEL J, STEVENS E, FORREST K, ROSZMAN TL: Daclizumab (Zenapax) inhibits early interleukin-2 receptor signal transduction events. Transpl. Immunol (2000) 8(3):153–159.
- VINCENTI F, KIRKMAN R, LIGHT S et al: Interleukin-2-receptor blockade with daclizumab to prevent acute rejection in renal transplantation. Daclizumab Triple Therapy Study Group. N Engl. I Med. (1998) 338(3):161–165.
- ••Pivotal trial with anti-IL-2R monoclonalantibodies and first important study using a humanised monoclonal antibodies.
- MATAS AJ, GILLINGHAM KJ, PAYNE WD, NAJARIAN JS: The impact of an acute rejection episode on long-term renal allograft survival (t1/2). Transplantation (1994) 57(6):857–859.
- ADU D, COCKWELL P, IVES NJ, SHAW J, WHEATLEY K: Interleukin-2 receptor monoclonal antibodies in renal transplantation: meta-analysis of randomised trials. Br. Med. J. (2003) 326(7393):789.
- WALTERS SJ, WHITFIELD M, AKEHURST RL, CHILCOTT JB: Economic implications of the use of basiliximab in addition to triple immunosuppressive therapy in renal allograft recipients: a UK perspective. Pharmacoeconomics (2003) 21(2):129–138.
- KEOWN PA, BALSHAW R, KRUEGER H, BALADI JF: Economic analysis of basiliximab in renal transplantation. Transplantation (2001) 71(10:1573–1579.
- VINCENTI F, RAMOS E, BRATTSTROM C et al.: Multicenter trial exploring calcineurin inhibitors avoidance in renal transplantation. Transplantation (2001) 71(9):1282–1287.
- TRAN HT, ACHARYA MK, MCKAY DB et al: Avoidance of cyclosporine in renal transplantation: effects of daclizumab, mycophenolate mofetil, and steroids. J. Am. Soc. Nephrol (2000) 11(10):1903–1909.
- SARWAL MM, VIDHUN JR, ALEXANDER SR et al.: Continued superior outcomes with modification and lengthened follow-up of a steroid-avoidance pilot with extended daclizumab induction in pediatric renal transplantation. Transplantation (2003) 76(9):1331–1339.
- •A good example of extended monoclonal antibody use suggesting applications other than induction therapy.
- PEARSON TC, MADSEN JC, LARSEN CP, MORRIS PJ, WOOD KJ: Induction of transplantation tolerance in adults using donor antigen and anti-CD4 monoclonal antibody. Transplantation (1992) 54(3):475–483.
- COSIMI AB, DELMONICO FL, WRIGHT JK et al.: Prolonged survival of nonhuman primate renal allograft recipients treated only with anti-CD4 monoclonal antibody. Surgery (1990) 108(2):406–413.
- DANTAL J, NININ E, HOURMANT M et al.: Anti-CD4 MoAb therapy in kidney transplantation-a pilot study in early prophylaxis of rejection. Transplantation (1996) 62(10):1502–1506.
- COOPERATIVE CLINICAL TRIALS IN TRANSPLANTATION RESEARCH GROUP: Murine OKT4A immunosuppression in cadaver donor renal allograft recipients. Transplantation (1997) 63(9):1243–1251.
- JUNE CH, LEDBETTER JA, GILLESPIE MM, LINDSTEN T, THOMPSON CB: T-cell proliferation involving the CD28 pathway is associated with cyclosporine-resistant interleukin 2 gene expression. Mol. Cell Biol. (1987) 7(12):4472–4481.
- JUNE CH, LEDBETTER JA, LINDSTEN T, THOMPSON CB: Evidence for the involvement of three distinct signals in the induction of IL-2 gene expression in human T lymphocytes. Immunol. (1989) 143(1):153–161.
- JUNE CH, BLUESTONE JA, NADLER LM, THOMPSON CB: The B7 and CD28 receptor families. Immunol. Today (1994) 15(7):321–331.
- JUNE CH, VANDENBERGHE P, THOMPSON CB: The CD28 and CTLA-4 receptor family. Chem. Immunol. (1994) 59:62–90.
- THOMPSON CB, LINDSTEN T, LEDBETTER JA et al.: CD28 activation pathway regulates the production of multiple T-cell-derived lymphokinesi cytokines. Proc. Natl. Acad. Sci. USA (1989) 86(4):1333–1337.
- BLAIR PJ, RILEY JL, CARROLL RG et al.: CD28 co-receptor signal transduction in T-cell activation. Biochem. Soc. Trans. (1997) 25(2):651–657.
- BLAIR PJ, RILEY JL, LEVINE BL et al.: CTLA-4 ligation delivers a unique signal to resting human CD4 T cells that inhibits interleukin-2 secretion but allows Bc1-X(L) induction. J. Immunol. (1998) 160(1):12–15.
- SAYEGH MH, AKALIN E,HANCOCK WW et al.: CD28-B7 blockade after alloantigenic challenge in vivo inhibits Thl cytokines but spares Th2. I Exp. Med. (1995) 181(5):1869–1874.
- SAYEGH MH, TURKA LA: T cell costimulatory pathways: promising novel targets for immunosuppression and tolerance induction. J. Am. Soc. Nephrol. (1995) 6(4):1143–1150.
- KIRK AD, TADAKI DK, CELNIKER A et al.: Induction therapy with monoclonal antibodies specific for CD80 and CD86 delays the onset of acute renal allograft rejection in non-human primates. Transplantation (2001) 72(3):377–384.
- KIRK AD, BLAIR PJ, TADAKI DK et al.: The role of CD154 in organ transplant rejection and acceptance. Philos. Trans. R. Soc. Lond. B. Biol. Sci. (2001) 356(1409):691–702.
- SCHOENBERGER SP, TOES RE, VAN DER VOORT El, OFFRINGA R, MELIEF CJ: T-cell help for cytotoxic T lymphocytes is mediated by CD4O-CD4OL interactions. Nature. (1998) 393(6684):480–483.
- MIYASHITA T, MCILRAITH MJ, GRAMMER AC et al.: Bidirectional regulation of human B cell responses by CD4O-CD40 ligand interactions. Immunol. (1997) 158(10):4620–4633.
- LIPSKY PE, ATTREP JF, GRAMMER AC, MCILRAITH MJ, NISHIOKA Y: Analysis of CD4O-CD40 ligand interactions in the regulation of human B cell function. Ann. NY Acad. Sci (1997) 815:372–383.
- MATZINGER P: Graft tolerance: a duel of two signals. Nat. Med. (1999) 5(6):616–617.
- ADAMS AB, SHIRASUGI N, DURHAM MM et al.: Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates. Diabetes (2002) 51(2):265–270.
- ABRAMS JR, LEBWOHL MG, GUZZO CA et al.: CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris. Clin. Invest. (1999) 103(9):1243–1252.
- ADAMS AB, SHIRASUGI N, DURHAM MM et al.: Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates. Diabetes (2002) 51(2): 265–270.
- VINCENTI F, DURBACH A, LARSEN C et al.: Study design and baseline characteristics of a multiple dose, randomized, controlled open-label study comparing a costimulation blocker based regimen of BMS-224818 (LEA29Y) versus cyclosporine in renal transplant. Am. J. Transplant. (2003) 3\(suppl 5):473.
- •First concerted effort to develop a costimulatory blockade monoclonal antibody for transplantation. Subsequent results of this trial will be closely watched.
- KIRK AD, HARLAN DM, ARMSTRONG NN et al.: CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc. Nati Acad. Sri. USA (1997) 94(16):8789–8794.
- KIRK AD, BURKLY LC, BATTY DS et al.: Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates. Nat. Med. (1999) 5(6):686–693.
- •The most definitive result from a preclinical anti-rejection trial using only monoclonal antibody therapy.
- KIRK AD, KNECHTLE SJ, SOLLINGER HW et al.: Preliminary results of the use of humanized anti-CD154 in human renal allotransplantation. Am. J. Transplant. (2001) l\(Suppl. 1):191.
- KAWAI T, ANDREWS D, COLVIN RB, SACHS DH, COSIMI AB: Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. Nat. Med. (2000) 6(2):114.
- HENN V, SLUPSKY JR, GRAFE M et al.: CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature. (1998) 391(6667):591–594.
- KALUNIAN KC, DAVIS JC JR, MERRILL JT et al.: Treatment of systemic lupus erythematosus by inhibition of T cell costimulation with anti-CD154: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. (2002) 46(12):3251–3258.
- FUGGLE SV, KOO DD: Cell adhesion molecules in clinical renal transplantation. Transplantation. (1998) 65(6):763–769.
- DUSTIN ML, SPRINGER TA: T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature. (1989) 341(6243):619–624.
- LO SK, VAN SEVENTER GA, LEVIN SM, WRIGHT SD: Two leukocyte receptors (CD1 1 a/CD18 and CD1 1 b/ CD18) mediate transient adhesion to endothelium by binding to different ligands. Immunol. (1989) 143(10):3325–3329.
- MENTZER SJ, GROMKOWSKI SH, KRENSKY AM, BURAKOFF SJ, MARTZ E: LFA1 membrane molecule in the regulation of homotypic adhesion of human B lymphocytes. I Immunol (1985) 135(1):9–11.
- DAVIGNON D, MARTZ E, REYNOLDS T, KURZINGER K, SPRINGER TA: Monoclonal antibody to a novel lymphocyte function-associated antigen (LFA1): mechanism of blockade of T-lymphocyte mediated killing and effects on other T and B lymphocyte functions. Immunol (1981) 127(2):590–595.
- HOURMANT M, BEDROSSIAN J, DURAND D et al: A randomized multicenter trial comparing leukocyte function-associated antigen-1 monoclonal antibody with rabbit antithymocyte globulin as induction treatment in first kidney transplantations. Transplantation (1996) 62(11):1565–1570.
- MICHALLET MC, PREVILLE X, FLACHER M, FOURNEL S, GENESTIER L, REVILLARD JP: Functional antibodies to leukocyte adhesion molecules in antithymocyte globulins. Transplantation (2003) 75(5):657–662.
- DEDRICK RL, WALICKE P, GAROVOY M: Anti-adhesion antibodies efalizumab, a humanized anti-CD1 la monoclonal antibody. Transpl. Immunol (2002) 9(2-4):181–186.
- DUSTIN ML, ROTHLEIN R, BHAN AK, DINARELLO CA, SPRINGER TA: Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). Immunol (1986) 137(1):245–254.
- COSIMI AB, CONTI D, DELMONICO FL et al: In vivo effects ofmonoclonal antibody to ICAM-1 (CD54)in nonhuman primates with renal allografts.Immunol (1990) 144(12):4604–4612.
- HAUG CE, COLVIN RB, DELMONICO FL et al: A Phase I trial of immunosuppression with anti-ICAM-1 (CD54) mAb in renal allograft recipients. Transplantation (1993) 55(4):766–772.
- SALMELA K, WRAMNER L, EKBERG H et al.: A randomized multicenter trial of the anti-ICAM-1 monoclonal antibody (enlimomab) for the prevention of acute rejection and delayed onset of graft function in cadaveric renal transplantation: a report of the European Anti-ICAM-1 Renal Transplant Study Group. Transplantation (1999) 67(5):729–736.
- GANNE V, SIDDIQIN, KAMAPLATH B et al.: Humanized anti-CD20 monoclonal antibody (Rituximab) treatment for post-transplant lymphoproliferative disorder. Clin. Transplant. (2003) 17(5):417–422.
- ALWAYN IP, XU Y, BASKER M et al.: Effects of specific anti-B anclior anti-plasma cell immunotherapy on antibody production in baboons: depletion of CD20-and CD22-positive B cells does not result in significantly decreased production of anti-alphaGal antibody. Xenotransplantation (2001) 8(3):157–171.
- SAWADA T, FUCHINOUE S, TERAOKA S: Successful A1-to-0 ABO-incompatible kidney transplantation after a preconditioning regimen consisting of anti-CD20 monoclonal antibody infusions, splenectomy, and double-filtration plasmapheresis. Transplantation (2002) 74(9):1207–1210.
- TYDEN G, KUMLIEN G, FEHRMAN I: Successful ABO-incompatible kidney transplantations without splenectomy using antigen-specific immunoadsorption and rituximab. Transplantation (2003) 76(4):730–731.
- BECKER YT, PIRSCH JD, SOLLINGER HW: Rituximab: a highly successful therapy for treatment of vascular rejection. Am. Transplant. (2003) 3\(suppl 5):476.
- SARWAL M, CHUA MS, KAMBHAM N et al.: Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling. N Engl. I Med. (2003) 349(2):125–138.
- HAO LM, WANG Y, GILL RG,LA ROSA FG, TALMAGE DW,LAFFERTY KJ: Role of lymphokine in islet allograft rejection. Transplantation (1990) 49(3):609–614.
- DIAMOND AS, GILL RG: An essential contribution by IFN-gamma to CD8+ T cell-mediated rejection of pancreatic islet allografts. Immunol (2000) 165(1):247–255.
- KIRK AD, HALE DA, HOFFMANN SC et al: Results from a human tolerance trial using Campath-1H with and without infliximab. Am. J. Transplant. (2002) 2\(Suppl. 2):379.
Websites
- http://www.ama-assn.org/ama/pub/article/ 4781–4661.html AMA-USAN website. Accessed (2004).
- http://www.immunetolerance.org/research/ solidorgan/trials/sachsl.html Immune Tolerance Network website. Accessed (2004).
- http://www.immunetolerance.org/eXpress/ research/ 192003-1/vincenti.html Immune Tolerance Network Newsletter, Vol. 1 Number 1, July 2003. Accessed (2004).