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Targeting major vault protein in senescence-associated apoptosis resistance

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Pages 479-484 | Published online: 31 Mar 2009

Bibliography

  • van Zon A, Mossink MH, Scheper RJ, et al. The vault complex. Cell Mol Life Sci 2003;60:1828-37
  • Hu Y, Stephen AG, Cao J, et al. A very early induction of major vault protein accompanied by increased drug resistance in U-937 cells. Int J Cancer 2002;97:149-56
  • Kickhoefer VA, Rajavel KS, Scheffer GL, et al. Vaults are up-regulated in multidrug-resistant cancer cell lines. J Biol Chem 1998;273:8971-4
  • Schroeijers AB, Siva AC, Scheffer GL, et al. The Mr 193,000 vault protein is up-regulated in multidrug-resistant cancer cell lines. Cancer Res 2000;60:1104-10
  • Mossink MH, van Zon A, Franzel-Luiten E, et al. Disruption of the murine major vault protein (MVP/LRP) gene does not induce hypersensitivity to cytostatics. Cancer Res 2002;62:7298-304
  • Mossink MH, de Groot J, van Zon A, et al. Unimpaired dendritic cell functions in MVP/LRP knockout mice. Immunology 2003;110:58-65
  • van Zon A, Mossink MH, Schoester M, et al. Efflux kinetics and intracellular distribution of daunorubicin are not affected by major vault protein/lung resistance-related protein (vault) expression. Cancer Res 2004;64:4887-92
  • Schroeijers AB, Reurs AW, Scheffer GL, et al. Up-regulation of drug resistance-related vaults during dendritic cell development. J Immunol 2002;168:1572-8
  • Kowalski MP, Dubouix-Bourandy A, Bajmoczi M, et al. Host resistance to lung infection mediated by major vault protein in epithelial cells. Science 2007;317:130-2
  • Mrazek J, Kreutmayer SB, Grasser FA, et al. Subtractive hybridization identifies novel differentially expressed ncRNA species in EBV-infected human B cells. Nucleic Acids Res 2007;35:e73. Published online on May 3, 2007 doi:10.1093/nar/gkm244
  • Kolli S, Zito CI, Mossink MH, et al. The major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signaling. J Biol Chem 2004;279:29374-85
  • Yu Z, Fotouhi-Ardakani N, Wu L, et al. PTEN associates with the vault particles in HeLa cells. J Biol Chem 2002;277:40247-52
  • Kim E, Lee S, Mian MF, et al. Crosstalk between Src and major vault protein in epidermal growth factor-dependent cell signalling. FEBS J 2006;273:793-804
  • Vasu SK, Rome LH. Dictyostelium vaults: disruption of the major proteins reveals growth and morphological defects and uncovers a new associated protein. J Biol Chem 1995;270:16588-94
  • MacFarlane M, Williams AC. Apoptosis and disease: a life or death decision. EMBO Rep 2004;5:674-8
  • Yeo EJ, Hwang YC, Kang CM, et al. Reduction of UV-induced cell death in the human senescent fibroblasts. Mol Cells 2000;10:415-22
  • Ryu SJ, Cho KA, Oh YS, Park SC. Role of Src-specific phosphorylation site on focal adhesion kinase for senescence-associated apoptosis resistance. Apoptosis 2006;11:303-13
  • Sakurai N, Utsumi T. Posttranslational N-myristoylation is required for the anti-apoptotic activity of human tGelsolin, the C-terminal caspase cleavage product of human gelsolin. J Biol Chem 2006;281:14288-95
  • Hampel B, Malisan F, Niederegger H, et al. Differential regulation of apoptotic cell death in senescent human cells. Exp Gerontol 2004;39:1713-21
  • Ryu SJ, Oh YS, Park SC. Failure of stress-induced downregulation of Bcl-2 contributes to apoptosis resistance in senescent human diploid fibroblasts. Cell Death Differ 2007;14:1020-8
  • Naderi J, Hung M, Pandey S. Oxidative stress-induced apoptosis in dividing fibroblasts involves activation of p38 MAP kinase and over-expression of Bax: resistance of quiescent cells to oxidative stress. Apoptosis 2003;8:91-100
  • Huang Y, Corbley MJ, Tang Z, et al. Down-regulation of p21WAF1 promotes apoptosis in senescent human fibroblasts: involvement of retinoblastoma protein phosphorylation and delay of cellular aging. J Cell Physiol 2004;201:483-91
  • Hampel B, Wagner M, Teis D, et al. Apoptosis resistance of senescent human fibroblasts is correlated with the absence of nuclear IGFBP-3. Aging Cell 2005;4:325-30
  • Ahn JS, Jang IS, Rhim JH, et al. Gelsolin for senescence-associated resistance to apoptosis. Ann NY Acad Sci 2003;1010:493-5
  • Ryu SJ, An HJ, Oh YS, et al. On the role of major vault protein in the resistance of senescent human diploid fibroblasts to apoptosis. Cell Death Differ 2008;15:1673-80
  • Kedersha NL, Rome LH. Isolation and characterization of a novel ribonucleoprotein particle: large structures contain a single species of small RNA. J Cell Biol 1986;103:699-709
  • Rome L, Kedersha N, Chugani D. Unlocking vaults: organelles in search of a function. Trends Cell Biol 1991;1:47-50
  • Kedersha NL, Heuser JE, Chugani DC, Rome LH. Vaults. III. Vault ribonucleoprotein particles open into flower-like structures with octagonal symmetry. J Cell Biol 1991;112:225-35
  • Kedersha NL, Miquel MC, Bittner D, Rome LH. Vaults. II. Ribonucleoprotein structures are highly conserved among higher and lower eukaryotes. J Cell Biol 1990;110:895-901
  • van Zon A, Mossink MH, Schoester M, et al. Structural domains of vault proteins: a role for the coiled coil domain in vault assembly. Biochem Biophys Res Commun 2002;291:535-41
  • Zheng CL, Sumizawa T, Che XF, et al. Characterization of MVP and VPARP assembly into vault ribonucleoprotein complexes. Biochem Biophys Res Commun 2005;326:100-7
  • Scheffer GL, Schroeijers AB, Izquierdo MA, et al. Lung resistance-related protein/major vault protein and vaults in multidrug-resistant cancer. Curr Opin Oncol 2000;12:550-6
  • Berger W, Elbling L, Micksche M. Expression of the major vault protein LRP in human non-small-cell lung cancer cells: activation by short-term exposure to antineoplastic drugs. Int J Cancer 2000;88:293-300
  • Laurencot CM, Scheffer GL, Scheper RJ, Shoemaker RH. Increased LRP mRNA expression is associated with the MDR phenotype in intrinsically resistant human cancer cell lines. Int J Cancer 1997;72:1021-6
  • Berger W, Spiegl-Kreinecker S, Buchroithner J, et al. Overexpression of the human major vault protein in astrocytic brain tumor cells. Int J Cancer 2001;94:377-82
  • Zurita AJ, Diestra JE, Condom E, et al. Lung resistance-related protein as a predictor of clinical outcome in advanced testicular germ-cell tumours. Br J Cancer 2003;88:879-86
  • Stein U, Jurchott K, Schlafke M, Hohenberger P. Expression of multidrug resistance genes MVP, MDR1, and MRP1 determined sequentially before, during, and after hyperthermic isolated limb perfusion of soft tissue sarcoma and melanoma patients. J Clin Oncol 2002;20:3282-92
  • Komarov PG, Shtil AA, Holian O, et al. Activation of the LRP (lung resistance-related protein) gene by short-term exposure of human leukemia cells to phorbol ester and cytarabine. Oncol Res 1998;10:185-92
  • Steiner E, Holzmann K, Pirker C, et al. SP-transcription factors are involved in basal MVP promoter activity and its stimulation by HDAC inhibitors. Biochem Biophys Res Commun 2004;317:235-43
  • Steiner E, Holzmann K, Pirker C, et al. The major vault protein is responsive to and interferes with interferon-γ-mediated STAT1 signals. J Cell Sci 2006;119:459-69
  • Stein U, Walther W, Laurencot CM, et al. Tumor necrosis factor-α and expression of the multidrug resistance-associated genes LRP and MRP. J Natl Cancer Inst 1997;89:807-13
  • Lange C, Walther W, Schwabe H, Stein U. Cloning and initial analysis of the human multidrug resistance-related MVP/LRP gene promoter. Biochem Biophys Res Commun 2000;278:125-33
  • Kickhoefer VA, Vasu SK, Rome LH. Vaults are the answer, what is the question? Trends Cell Biol 1996;6:174-8
  • Steiner E, Holzmann K, Elbling L, et al. Cellular functions of vaults and their involvement in multidrug resistance. Curr Drug Targets 2006;7:923-34
  • Herrmann C, Golkaramnay E, Inman E, et al. Recombinant major vault protein is targeted to neuritic tips of PC12 cells. J Cell Biol 1999;144:1163-72
  • Hamill DR, Suprenant KA. Characterization of the sea urchin major vault protein: a possible role for vault ribonucleoprotein particles in nucleocytoplasmic transport. Dev Biol 1997;190:117-28
  • Chugani DC, Rome LH, Kedersha NL. Evidence that vault ribonucleoprotein particles localize to the nuclear pore complex. J Cell Sci 1993;106(Pt 1):23-9
  • Abbondanza C, Rossi V, Roscigno A, et al. Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cell. J Cell Biol 1998;141:1301-10
  • Berger W, Steiner E, Grusch M, et al. Vaults and the major vault protein: novel roles in signal pathway regulation and immunity. Cell Mol Life Sci 2009;66:43-61
  • Scheper RJ, Broxterman HJ, Scheffer GL, et al. Overexpression of a Mr 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance. Cancer Res 1993;53:1475-9
  • Scheffer GL, Wijngaard PL, Flens MJ, et al. The drug resistance-related protein LRP is the human major vault protein. Nat Med 1995;1:578-82
  • Siva AC, Raval-Fernandes S, Stephen AG, et al. Up-regulation of vaults may be necessary but not sufficient for multidrug resistance. Int J Cancer 2001;92:195-202
  • Izquierdo MA, Scheffer GL, Flens MJ, et al. Broad distribution of the multidrug resistance-related vault lung resistance protein in normal human tissues and tumors. Am J Pathol 1996;148:877-87
  • Izquierdo MA, Shoemaker RH, Flens MJ, et al. Overlapping phenotypes of multidrug resistance among panels of human cancer-cell lines. Int J Cancer 1996;65:230-7
  • Ohno N, Tani A, Uozumi K, et al. Expression of functional lung resistance-related protein predicts poor outcome in adult T-cell leukemia. Blood 2001;98:1160-5
  • Kitazono M, Okumura H, Ikeda R, et al. Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells. Int J Cancer 2001;91:126-31
  • Kitazono M, Sumizawa T, Takebayashi Y, et al. Multidrug resistance and the lung resistance-related protein in human colon carcinoma SW-620 cells. J Natl Cancer Inst 1999;91:1647-53
  • Sunnaram BL, Gandemer V, Sebillot M, et al. LRP overexpression in monocytic lineage. Leuk Res 2003;27:755-9
  • Yi C, Li S, Chen X, et al. Major vault protein, in concert with constitutively photomorphogenic 1, negatively regulates c-Jun-mediated activator protein 1 transcription in mammalian cells. Cancer Res 2005;65:5835-40
  • Kedersha NL, Hill DF, Kronquist KE, Rome LH. Subpopulations of liver coated vesicles resolved by preparative agarose gel electrophoresis. J Cell Biol 1986;103:287-97
  • Suprenant KA. Vault ribonucleoprotein particles: sarcophagi, gondolas, or safety deposit boxes? Biochemistry 2002;41:14447-54
  • Izquierdo MA, Scheffer GL, Flens MJ, et al. Relationship of LRP-human major vault protein to in vitro and clinical resistance to anticancer drugs. Cytotechnology 1996;19:191-7

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