Autoimmune diseases: MIF as a therapeutic target

Bibliography

• Janeway C. Autoimmunity and transplantation. In: Janeway C, Travers P, Walport M, Shlomchik M, editors, Immunobiology, Garland, New York, NY; 2005. p. 557-612
   Google Scholar
• Bucala R, Lolis E. MIF: a critical component of autoimmune inflammatory diseases. Drug News Perspect 2005;18(7):417-26
   PubMedGoogle Scholar
• Feldmann M, Maini RN. Anti-TNFalpha therapy of rheumatoid arthritis: what have we learned? Annu Rev Immunol 2001;19:163-96
   PubMed Web of Science ®Google Scholar
• Nishimoto N, Miyasaka N, Yamamoto K, Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy. Mod Rheumatol 2009;19(1):12-9
   PubMed Web of Science ®Google Scholar
• Andreakos ET, Foxwell BM, Brennan FM, Cytokines and anti-cytokine biologicals in autoimmunity: present and future. Cytokine Growth Factor 2002;13(4-5):299-313
   PubMedGoogle Scholar
• Waldner H. The role of innate immune responses in autoimmune disease development. Autoimmun Rev 2009;8(5):400-4
   PubMedGoogle Scholar
• Dinarello CA, Wolff SM. The role of interleukin-1 in disease. N Engl J Med 1993;328:106-13
   PubMed Web of Science ®Google Scholar
• Feldmann M, Brennan FM, Paleolog E, Anti-TNFalpha therapy of rheumatoid arthritis: what can we learn about chronic disease? Novartis Found Symp 2004;256:53-69
   PubMedGoogle Scholar
• Calandra T, Roger T. Macrophage migration inhibitory factor: a regulator of innate immunity. Nat Rev Immunol 2003;3:791-800
   PubMed Web of Science ®Google Scholar
• Lolis E, Bucala R. Macrophage migration inhibitory factor. Expert Opin Ther Targets 2003;7:153-64
   PubMed Web of Science ®Google Scholar
• Bozza M, Satoskar AR, Lin G, Targeted disruption of migration inhibitory factor gene reveals its critical role in sepsis. J Exp Med 1999;189:341-6
   PubMed Web of Science ®Google Scholar
• Mitchell RA, Liao H, Chesney J, Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: regulatory role in the innate immune response. Proc Natl Acad Sci USA 2002;99:345-50
   PubMed Web of Science ®Google Scholar
• Bernhagen J, Calandra T, Mitchell RA, MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia. Nature 1993;365:756-9
   PubMed Web of Science ®Google Scholar
• Calandra T, Bernhagen J, Mitchell RA, Bucala R. The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor. J Exp Med 1994;179:1895-902
   PubMed Web of Science ®Google Scholar
• Calandra T, Bernhagen J, Metz CN, MIF as a glucocorticoid-induced modulator of cytokine production. Nature 1995;377:68-71
   PubMed Web of Science ®Google Scholar
• Donnelly SC, Haslett C, Reid PT, Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome. Nat Med 1997;3:320-3
   PubMed Web of Science ®Google Scholar
• Daun JM, Cannon JG. Macrophage migration inhibitory factor antagonizes hydrocortisone-induced increases in cytosolic IκBalpha. Am J Physiol 2000;279:R1043-9
   PubMed Web of Science ®Google Scholar
• Wang L, Das H, Kamath A, Human Vgamma2Vdelta2 T cells augment MIF secretion and counteract the inhibitory effect of glucocorticoids on IL-1beta and TNF-alpha production. J Immunol 2002;168:4889-96
   PubMedGoogle Scholar
• Mitchell RA, Metz CN, Peng T, Bucala R. Sustained mitogen-activated protein kinase (MAPK) and cytoplasmic phospholipase A2 activation by macrophage migration inhibitory factor (MIF). Regulatory role in cell proliferation and glucocorticoid action. J Biol Chem 1999;274:18100-6
   PubMed Web of Science ®Google Scholar
• Flaster H, Bernhagen J, Calandra T, Bucala R. The macrophage migration inhibitory factor-glucocorticoid dyad: regulation of inflammation and immunity. Mol Endocrinol 2007;21(6):1267-80
   PubMedGoogle Scholar
• Roger T, Chanson AL, Knaup-Reymond M, Calandra T. Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1. Eur J Immunol 2005;35(12):3405-13
   PubMedGoogle Scholar
• Aeberli D, Yang Y, Mansell A, Endogenous macrophage migration inhibitory factor modulates glucocorticoid sensitivity in macrophages via effects on MAP kinase phosphatase-1 and p38 MAP kinase. FEBBS Lett 2006;580(3):974-80
   PubMedGoogle Scholar
• Leng L, Wang W, Roger T, Glucocorticoid-induced MIF expression by human CEM T cells. Cytokine 2009;48(3):177-85
   PubMedGoogle Scholar
• Bacher M, Meinhardt A, Lan HY, Migration inhibitory factor expression in experimentally induced endotoxemia. Am J Pathol 1997;150:235-46
   PubMed Web of Science ®Google Scholar
• Fingerle-Rowson G, Koch P, Bikoff R, Regulation of macrophage migration inhibitory factor expression by glucocorticoids in vivo. Am J Pathol 2003;162:47-56
   PubMed Web of Science ®Google Scholar
• Suzuki M, Sugimoto H, Nakagawa A, Crystal structure of the macrophage migration inhibitory factor from rat liver. Nat Struct Biol 1996;3:259-66
   PubMedGoogle Scholar
• Sun HW, Bernhagen J, Bucala R, Lolis E. Crystal structure at 2.6-Å resolution of human macrophage migration inhibitory factor. Proc Natl Acad Sci USA 1996;93:5191-6
   PubMed Web of Science ®Google Scholar
• Leng L, Metz CN, Fang Y, MIF signal transduction initiated by binding to CD74. J Exp Med 2003;197:1467-76
   PubMed Web of Science ®Google Scholar
• Kleemann R, Hausser A, Geiger G, Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1. Nature 2000;408:211-6
   PubMed Web of Science ®Google Scholar
• Hudson JD, Shoaibi MA, Maestro R, A proinflammatory cytokine inhibits p53 tumor suppressor activity. J Exp Med 1999;190:1375-82
   PubMed Web of Science ®Google Scholar
• Bernhagen J, Krohn R, Lue H, MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nat Med 2007;13:587-96
   PubMed Web of Science ®Google Scholar
• Weber C, Kraemer S, Drechsler M, Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment. Proc Natl Acad Sci USA 2008;105(42):16278-83
   PubMedGoogle Scholar
• Bacher M, Metz CN, Calandra T, An essential regulatory role for macrophage migration inhibitory factor in T-cell activation. Proc Natl Acad Sci USA 1996;93:7849-54
   PubMed Web of Science ®Google Scholar
• Bernhagen J, Bacher M, Calandra T, An essential role for macrophage migration inhibitory factor in the tuberculin delayed-type hypersensitivity reaction. J Exp Med 1996;183:277-82
   PubMed Web of Science ®Google Scholar
• Abe R, Peng T, Sailors J, Regulation of the CTL response by macrophage migration inhibitory factor. J Immunol 2001;166:747-53
   PubMed Web of Science ®Google Scholar
• Denkinger CM, Denkinger M, Kort JJ, In vivo blockade of macrophage migration inhibitory factor ameliorates acute experimental autoimmune encephalomyelitis by impairing the homing of encephalitogenic T cells to the central nervous system. J Immunol 2003;170:1274-82
   PubMedGoogle Scholar
• Mikulowska A, Metz CN, Bucala R, Holmdahl R. Macrophage migration inhibitory factor is involved in the pathogenesis of collagen type II-induced arthritis in mice. J Immunol 1997;158:5514-7
   PubMed Web of Science ®Google Scholar
• de Jong YP, Abadia-Molina AC, Satoskar AR, Development of chronic colitis is dependent on the cytokine MIF. Nat Immunol 2001;2:1061-6
   PubMed Web of Science ®Google Scholar
• Nishihira J, Ogata A. Macrophage migration inhibitory factor as a target molecule in multiple sclerosis. Curr Opin Invest Drugs 2001;2:778-82
   PubMedGoogle Scholar
• Leech M, Metz C, Santos L, Involvement of macrophage migration inhibitory factor in the evolution of rat adjuvant arthritis. Arthritis Rheum 1998;41:910-7
   PubMed Web of Science ®Google Scholar
• Ichiyama H, Onodera S, Nishihira J, Inhibition of joint inflammation and destruction induced by anti-type II collagen antibody/lipopolysaccharide (LPS)-induced arthritis in mice due to deletion of macrophage migration inhibitory factor (MIF). Cytokine 2004;26:187-94
   PubMed Web of Science ®Google Scholar
• Leech M, Metz C, Hall P, Macrophage migration inhibitory factor in rheumatoid arthritis: evidence of proinflammatory function and regulation by glucocorticoids. Arthritis Rheum 1999;42:1601-8
   PubMed Web of Science ®Google Scholar
• Morand EF. New therapeutic target in inflammatory disease: macrophage migration inhibitory factor. Intern Med J 2005;35:419-26
   PubMed Web of Science ®Google Scholar
• Morand EF, Leech M, Weedon H, Macrophage migration inhibitory factor in rheumatoid arthritis: clinical correlations. Rheumatology 2002;41(5):558-62
   PubMedGoogle Scholar
• Tanasescu C, Jurcut C, Jurcut R, Ginghina C. Vascular disease in rheumatoid arthritis: from subclinical lesion to cardiovascular risk. Eur J Intern Med 2009;20(4):348-54
   PubMedGoogle Scholar
• Atsumi T, Cho YR, Leng L, The proinflammatory cytokine macrophage migration inhibitory factor regulates glucose metabolism during systemic inflammation. J Immunol 2007;179(8):5399-406
   PubMedGoogle Scholar
• Chen Z, Sakuma M, Zago AC, Evidence for a role of macrophage migration inhibitory factor in vascular disease. Arterioscler Thromb Vasc Biol 2007;24(4):709-14
   Google Scholar
• Wijbrandts CA, van Leuven SI, Boom HD, Sustained changes in lipid profile and macrophage migration inhibitory factor (MIF) levels after anti-TNF therapy in rheumatoid arthritis. Ann Rheum Dis 2009;68(8):1316-21
   PubMedGoogle Scholar
• Nishihira J, Mitsuyama K. Overview of the role of macrophage migration inhibitory factor in inflammatory bowel disease. Curr Pharm Des 2009;15(18):2104-9
   PubMedGoogle Scholar
• Kitaichi N, Kotake S, Mizue Y, Increase of macrophage migration inhibitory factor in sera of patients with iridocyclitis. Br J Ophthalmol 2000;84:1423-5
   PubMedGoogle Scholar
• Niino M, Ogata A, Kikuchi S, Macrophage migration inhibitory factor in the cerebrospinal fluid of patients with conventional and optic-spinal forms of multiple sclerosis and neuro-Behcet's disease. J Neurol Sci 2000;179:127-31
   PubMed Web of Science ®Google Scholar
• Kotake S, Kitaichi N, Ohno S. Macrophage migration inhibitory factor in uveitis. Int Ophthalmol Clin 2002;42:99-103
   PubMedGoogle Scholar
• Nicoletti F, Créange A, Orlikowski D, Macrophage migration inhibitory factor (MIF) seems crucially involved in Guillain-Barré syndrome and experimental allergic neuritis. J Neuroimmunol 2005;168(1-2):168-74
   PubMedGoogle Scholar
• Lan HY, Bacher M, Yang N, The pathogenic role of macrophage migration inhibitory factor in immunologically induced kidney disease in the rat. J Exp Med 1997;185:1455-65
   PubMed Web of Science ®Google Scholar
• Lan H. Role of macrophage migration inhibitory factor in kidney disease. Nephron Exp Nephrol 2008;109:e79-83
   Google Scholar
• Shlomchik M, Craft J, Mamula M. From T to B and back again: positive feedback in systemic autoimmune disease. Nat Immunol 2001;1:147-53
   Google Scholar
• Foote A, Briganti EM, Kipen Y, Macrophage migration inhibitory factor in systemic lupus erythematosus. J Rheumatol 2004;31:268-73
   PubMed Web of Science ®Google Scholar
• Hoi AY, Hickey MJ, Hall P, Macrophage migration inhibitory factor deficiency attenuates macrophage recruitment, glomerulonephritis, and lethality in MRL/lpr mice. J Immunol 2006;177(8):5687-96
   PubMedGoogle Scholar
• Becker H, Maaser C, Mickholz E, Relationship between serum levels of macrophage migration inhibitory factor and the activity of antineutrophil cytoplasmic antibody-associated vasculitides. Clin Rheumatol 2006;25(3):368-72
   PubMedGoogle Scholar
• Becker H, Willeke P, Schotte H, Macrophage migration inhibitory factor may contribute to vasculopathy in systemic sclerosis. Clin Rheumatol 2008;27(10):1307-11
   PubMedGoogle Scholar
• Stosic-Gruijcic S, Stojanovic I, Maksimovic-Ivanic D, Macrophage migration inhibitory factor is necessary for progression of autoimmune diabetes mellitus. J Cell Physiol 2008;215(3):665-75
   PubMedGoogle Scholar
• Bojunga J, Kusterer K, Bacher M, Macrophage migration inhibitory factor and development of type-1 diabetes in non-obese diabetic mice. Cytokine 2003;21:179-86
   PubMedGoogle Scholar
• Baugh JA, Chitnis S, Donnelly SC, A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis. Genes Immun 2002;3:170-6
   PubMed Web of Science ®Google Scholar
• De Benedetti F, Meazza C, Vivarelli M, Functional and prognostic relevance of the –173 polymorphism of the macrophage migration inhibitory factor gene in systemic juvenile idiopathic arthritis. Arthritis Rheum 2003;48:1398-407
   PubMed Web of Science ®Google Scholar
• Donn R, Alourfi Z, Zeggini E, A functional promoter haplotype of macrophage migration inhibitory factor is linked and associated with juvenile idiopathic arthritis. Arthritis Rheum 2004;50:1604-10
   PubMed Web of Science ®Google Scholar
• Stosic-Gruijcic S, Stojanovic I, Nicoletti F. MIF in autoimmunity and novel therapeutic approaches. Autoimmun Rev 2009;8(3):244-9
   PubMedGoogle Scholar
• Radstake TR, Sweep FC, Welsing P, Correlation of rheumatoid arthritis severity with the genetic functional variants and circulating levels of macrophage migration inhibitory factor. Arthritis Rheum 2005;52:3020-9
   PubMed Web of Science ®Google Scholar
• Vivarelli M, D'Urbano LE, Insalaco A, Macrophage migration inhibitory factor (MIF) and oligoarticular juvenile idiopathic arthritis (o-JIA): association of MIF promoter polymorphisms with response to intra-articular glucocorticoids. Clin Exp Rheumatol 2007;25(5):775-81
   PubMedGoogle Scholar
• Donn RP, Plant D, Jury F, Macrophage migration inhibitory factor gene polymorphism is associated with psoriasis. J Invest Dermatol 2004;123:484-7
   PubMed Web of Science ®Google Scholar
• Donn RP, Shelley E, Ollier WE, Thomson W. A novel 5′-flanking region polymorphism of macrophage migration inhibitory factor is associated with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 2001;44:1782-5
   PubMedGoogle Scholar
• Nohara H, Okayama N, Inoue N, Association of the –173G/C polymorphism of the macrophage migration inhibitory factor gene with ulcerative colitis. J Gastroenterol 2004;39:242-6
   PubMed Web of Science ®Google Scholar
• Dambacher J, Staudinger T, Seiderer J, Macrophage migration inhibitory factor (MIF) –173G/C promotor polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease. Inflamm Bowel Dis 2007;13:71-82
   PubMedGoogle Scholar
• Griga T, Wilkens C, Wirkus N, A polymorphism in the macrophage migration inhibitory factor gene is involved in the genetic predisposition of Crohn's disease and associated with cumulative steroid doses. Hepatogastroenterology 2007;54(75):784-6
   PubMedGoogle Scholar
• Mizue Y, Ghani S, Leng L, Role for macrophage migration inhibitory factor in asthma. Proc Natl Acad Sci USA 2005;102(4):14410-5
   PubMedGoogle Scholar
• Wu SP, Leng L, Feng Z, Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma. Arthritis Rheum 2006;54(11):3661-9
   PubMedGoogle Scholar
• Hizawa N, Yamaguchi E, Takahashi D, Functional polymorphisms in the promoter region of macrophage migration inhibitory factor and atopy. Am J Respir Crit Care Med 2004;169:1014-8
   PubMed Web of Science ®Google Scholar
• Amoli M, Donn RP, Thomson W, Macrophage migration inhibitory factor gene polymorphism is associated with sarcoidosis in biopsy proven erythema nodosum. J Rheumatol 2002;29:1671-3
   PubMed Web of Science ®Google Scholar
• Jawaheer D, Gregersen P. The search for rheumatoid arthritis susceptibility genes: a call for global collaboration. Arthritis Rheum 2002;46:582-4
   PubMedGoogle Scholar
• Gregersen P, Bucala R. MIF, MIF alleles, and the genetics of inflammatory disorders: incorporating disease outcome into the definition of phenotype. Arthritis Rheum 2003;48:1171-76
   PubMed Web of Science ®Google Scholar
• Mcguire W, Hill AV, Allsopp CE, Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. Nature 1994;371:508-10
   PubMed Web of Science ®Google Scholar
• Leech M, Metz C, Bucala R, Morand EF. Regulation of macrophage migration inhibitory factor by endogenous glucocorticoids in rat adjuvant-induced arthritis. Arthritis Rheum 2000;43:827-33
   PubMed Web of Science ®Google Scholar
• Ramanujam M, Davidson A. Targeting of the immune system in systemic lupus erythematosus. Expert Rev Mol Med 2008;10:e2. Published online 21 Jan 2008, doi: 10.1017/S1462399408000562
   Google Scholar
• Aringer M, Steiner G, Graninger WB, Effects of short-term infliximab therapy on autoantibodies in systemic lupus erythematosus. Arthritis Rheum 2007;56(1):274-9
   PubMedGoogle Scholar
• Calandra T, Echtenacher B, Roy DL, Protection from septic shock by neutralization of macrophage migration inhibitory factor. Nat Med 2000;6:164-9
   PubMed Web of Science ®Google Scholar
• Baxter International, Inc. News & Analysis. Anti-MIF technology licensed to large pharmaceutical company. Cancer Weekly, 10 April 2003
   Google Scholar
• Swope MD, Lolis E. Macrophage migration inhibitory factor: cytokine, hormone, or enzyme. Rev Physiol Biochem Pharmacol 1999;139:1-32
   PubMed Web of Science ®Google Scholar
• Rosengren E, Bucala R, Aman P, The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction. Mol Med 1996;2:143-9
   PubMed Web of Science ®Google Scholar
• Shi X, Leng L, Wang T, CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. Immunity 2006;25(4):595-606
   PubMedGoogle Scholar
• Fingerle-Rowson G, Kaleswarapu DR, Schlander C, A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation. Mol Cell Biol 2009;29(7):1922-32
   PubMedGoogle Scholar
• Scallon B, Cai A, Solowski N, Binding and functional comparisons of two types of tumor necrosis factor antagonists. J Pharm Exp Ther 2002;301:418-26
   PubMed Web of Science ®Google Scholar
• Senter PD, Al-Abed Y, Metz CN, Inhibition of macrophage migration inhibitory factor (MIF) tautomerase and biological activities by acetaminophen metabolites. Proc Natl Acad Sci USA 2002;99:144-9
   PubMed Web of Science ®Google Scholar
• Lubetsky JB, Dios A, Han J, The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents. J Biol Chem 2002;277:24976-82
   PubMed Web of Science ®Google Scholar
• Cvetkovic I, Stosic-Grujicic S. Neutralization of macrophage migration inhibitory factor-novel approach for the treatment of immunoinflammatory disorders. Int Immunopharmacol 2006;6(10):1527-34
   PubMedGoogle Scholar
• Arjona A, Foellmer HG, Town T, Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion. J Clin Invest 2007;117(10):3059-66
   PubMedGoogle Scholar
• Dagia NM, Kamath DV, Bhatt P, A fluorinated analog of ISO-1 blocks the recognition and biological function of MIF and is orally efficacious in a murine model of colitis. Eur J Pharmacol 2009;607(1-3):201-12
   PubMedGoogle Scholar
• Cournia Z, Leng L, Gandavadi S, Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screening. J Med Chem 2009;52(2):416-24
   PubMedGoogle Scholar
• Orita M, Yamamoto S, Katayama N, Fujita S. Macrophage migration inhibitory factor and the discovery of tautomerase inhibitors. Curr Pharm Res 2002;8:1297-317
   PubMed Web of Science ®Google Scholar
• Winner M, Meier J, Zierow S, A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells. Cancer Res 2008;68(18):7253-7
   PubMedGoogle Scholar
• Stein R, Mattes MJ, Cardillo TM, CD74: a new candidate target for the immunotherapy of B-cell neoplasms. Clin Cancer Res 2007;13(18 Pt 2):5556s-63s
   PubMed Web of Science ®Google Scholar
• Coleman AM, Rendon BE, Zhao M, Cooperative regulation of non-small cell lung carcinoma angiogenic potential by macrophage migration inhibitory factor and its homolog, D-dopachrome tautomerase. J Immunol 2008;181(4):2330-7
   PubMedGoogle Scholar