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Editorial

The road to load late-onset Alzheimer's disease and a possible way to block it

, PhD, FRSC
Pages 1257-1260 | Published online: 02 Oct 2007

Bibliography

  • ASHE KH: C impairment in transgenic Aβ and tau models of Alzheimer's disease. In: Alzheimer's Disease: Advances in Genetics Molecular and Cellular Biology. Sisoda SS, Tanzi RE (Eds), Springer Science+Business Media LLC, New York (2007):77-91.
  • KLEIN WL, LACOR PN, DE FELICE FG et al.: Molecules that disrupt memory circuits in Alzheimer's disease: the attack on synapses by Aβ oligomers (ADDLs). In: Memories: Molecules and Circuits. Bontempi B, Silva AJ, Christen Y (Eds), Springer Verlag, Berlin, Heidelberg (2007):155-179.
  • STEWARD O, SCHUMAN EM: Protein synthesis at synaptic sites on dendrites. Annu. Rev. Neurosci. (2001) 24:299-325.
  • CAO Q, HUANG YS, KAN MC et al.: Amyloid precursor protein proteins anchor CPEB to membranes and promote polyadenylation-induced translation. Mol. Cell. Biol. (2005) 25:10930-10939.
  • GLABE C, BUSH AI: Aβ structure and aggregation. In: Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology. Sisoda SS, Tanzi RE (Eds), Springer Science+Business Media LLC, New York (2007):113-131.
  • DEANE R, WU Z, ZLOKOVIC BV: RAGE (Yin) versus LRP(Yang) balance regulates Alzheimer amyloid {β}-peptide clearance through transport across the blood–brain barrier. Stroke (2004) 35:2628-2631.
  • DEANE R, ZLOKOVIC BV: Role of the blood–brain barrier in the pathogenesis of Alzheimer's disease. Curr. Alzheimer Res. (2007) 4:191-197.
  • BERTRAM L: The genetics of Alzheimer's disease. In: Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology. Sisoda SS, Tanzi RE (Eds), Springer Science+Business Media LLC, New York (2007):1-16.
  • CHIARINI A, DAL PRA I, WHITFIELD JF et al.: The killing of neurons by β amyloid peptides, prions, and pro-inflammatory cytokines. Ital. J. Anat. Embryol. (2006) 111:221-246.
  • CHO HJ, KIM SK, JIN SM et al.: IFN-γ-induced BACE1 expression is mediated by activation of JAK2 and ERK1/2 signaling pathways and direct binding of STAT to BACE1 promoter in astrocytes. Glia (2007) 55:253-262.
  • HONG HS, HWANG EM, SIM HJ et al.: Interferon γ stimulates β-secretase and sAPP β production in astrocytes. Biochem. Biophys. Res. Commun. (2003) 307:922-927.
  • LAMERE CA, LOPERA F, KOSIK KS et al.: The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology. Nat. Med. (1996) 2:1146-1150.
  • SCHEUNER D, ECKMAN C, JENSEN M et al.: Secreted amyloid β protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. (1996) 2:864-870.
  • WOLOZIN B, KELLMAN W, ROUSSEAU P et al.: Decreased prevalence of Alzheimer's disease associated with 3-hydroxy-3-methyl glutaryl coenzyme A reductase inhibitors. Arch. Neurol. (2000) 57:1439-1443.
  • WHITFIELD JF: Can statins put the brakes on Alzheimer's disease? Expert Opin. Investig. Drugs (2006) 15:1479-1485.
  • ZIGMAN WB, SCHUPF N, JENKINS EC et al.: Cholesterol level, statin use and Alzheimer's disease in adults with Down's syndrome. Neurosci. Lett. (2007) 416:2179-284.
  • HEAD E, LOTT IT: Down's syndrome and β-amyloid deposition. Curr. Opin. Neurol. (2004) 17:95-100.
  • GORITZ C, THIEBAUT R, TESSIER LC et al.: Glia-induced neuronal differentiation by transcriptional regulation. Glia (2007) 55:1108-1122.
  • MAUCH DH, NAGLER K, SCHUMACHER S et al.: CNS synaptogenesis promoted by glia-derived cholesterol. Science (2001) 294:1354-1357.
  • BJORKHEM I, MEANEY S: Brain cholesrterol; long secret life behind a barrier. Arter-ioscler. Thromb. Vasc. Biol. (2004) 24:1-11.
  • ZLOKOVIC BV: Neurovascualr mechanisms of Alzheimer's neurodegeneration. Trends Neurosci. (2005) 29:202-208.
  • DONAHUE JE, FLAHERTY SL, JOHANSON CE et al.: RAGE, LRP, and amyloid protein in Alzheimer's disease. Acta Neuropathol. (2006) 112:405-415.

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