Newer targets for modulation of intraocular pressure: focus on adenosine receptor signaling pathways

Bibliography

• Sommer A. Intraocular pressure and glaucoma. Am J Ophthalmol 1989;107:186-8
   PubMed Web of Science ®Google Scholar
• Schwartz K, Budenz D. Current management of glaucoma. Curr Opin Ophthalmol 2004;15:119-26
   PubMedGoogle Scholar
• Gliklich RE, Steinmann WC, Spaeth GL. Visual field change in low-tension glaucoma over a five-year follow-up. Ophthalmol 1989;96:316-20
   PubMedGoogle Scholar
• Overby DR, Stamer WD, Johnson M. The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium. Exp Eye Res 2009;88:656-70
   PubMed Web of Science ®Google Scholar
• Maepea O, Bill A. Pressures in the juxtacanalicular tissue and schlemm's canal in monkeys. Exp Eye Res 1992;54:879-83
   PubMed Web of Science ®Google Scholar
• Pedrigi RM, Simon D, Reed A, et al. A model of giant vacuole dynamics in human schlemm's canal endothelial cells. Exp Eye Res 2011;92(1):57-66
   PubMedGoogle Scholar
• Epstein DL, Rohen JW. Morphology of the trabecular meshwork and inner-wall endothelium after cationized ferritin perfusion in the monkey eye. Invest Ophthalmol Vis Sci 1991;32:160-71
   PubMed Web of Science ®Google Scholar
• Lütjen-Drecoll E, Shimizu T, Rohrbach M, et al. Quantitative analysis of “plaque material” in the inner and outer wall of schlemm's canal in normal and glaucomatous eyes. Exp Eye Res 1986;42:443-55
   PubMed Web of Science ®Google Scholar
• Ferrer E. Trabecular meshwork as a new target for the treatment of glaucoma. Drug News Perspect 2006;19(3):151-8
   PubMedGoogle Scholar
• Saccà SC, Izzotti A. Focus on molecular events in the anterior chamber leading to glaucoma. Cell Mol Life Sci 2013. [Epub ahead of print]
   PubMedGoogle Scholar
• Tan JC, Peters DM, Kaufman PL. Recent developments in understanding the pathophysiology of elevated intraocular pressure. Curr Opin Ophthalmol 2006;17(2):168-74
   PubMed Web of Science ®Google Scholar
• Wiederholt M, Thieme H, Stumpff F. The regulation of trabecular meshwork and ciliary muscle contractility. Prog Retin Eye Res 2000;19:271-95
   PubMed Web of Science ®Google Scholar
• Braun JS. Ecto-5'-nucleotidase-positive cells in the choroid and ciliary body of the rat eye. Anat Rec (Hoboken) 2010;293:379-82
   PubMedGoogle Scholar
• Li A, Leung CT, Peterson-Yantorno K, et al. Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow. J Cell Physiol 2012;227(1):172-82
   PubMedGoogle Scholar
• Luna C, Li G, Qiu J, et al. Extracellular release of ATP mediated by cyclic mechanical stress leads to mobilization of AA in trabecular meshwork cells. Invest Ophthalmol Vis Sci 2009;50(12):5805-10
   PubMed Web of Science ®Google Scholar
• Li A, Leung CT, Peterson-Yantorno K, et al. Cytoskeletal dependence of adenosine triphosphate release by human trabecular meshwork cells. Invest Ophthalmol Vis Sci 2011;52(11):7796-8005
   Google Scholar
• Zhang X, Li A, Ge J, et al. Acute increase of intraocular pressure releases ATP into the anterior chamber. Exp Eye Res 2007;85(5):637-43
   PubMedGoogle Scholar
• Li A, Zhang X, Zheng D, et al. Sustained elevation of extracellular ATP in aqueous humor from humans with primary chronic angle-closure glaucoma. Exp Eye Res 2011;93(4):528-33
   PubMedGoogle Scholar
• Daines BS, Kent AR, McAleer MS, et al. Intraocular adenosine levels in normal and ocular hypertensive patients. J Ocul Pharmacol Ther 2003;19:113-19
   PubMed Web of Science ®Google Scholar
• Londos C, Cooper DM, Wolff J. Subclasses of external adenosine receptors. Proc Natl Acad Sci USA 1980;77(5):2551-4
   PubMedGoogle Scholar
• Fredholm BB. Adenosine receptors. Med Biol 1982;60(6):289-93
   PubMedGoogle Scholar
• Daly JW, Butts-Lamb P, Padgett W. Subclasses of adenosine receptors in the central nervous system: interaction with caffeine and related methylxanthines. Cell Mol Neurobiol 1983;3(1):69-80
   PubMedGoogle Scholar
• Zhou QY, Li C, Olah ME, et al. Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor. Proc Natl Acad Sci USA 1992;15:89(16):7432-6
   Google Scholar
• Schlötzer-Schrehardt U, Zenkel M, Decking U, et al. Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma. Invest Ophthalmol Vis Sci 2005;46(6):2023-34
   PubMedGoogle Scholar
• Kvanta A, Seregard S, Sejersen S, et al. Localization of adenosine receptor messenger RNAs in the rat eye. Exp Eye Res 1997;65:595-602
   PubMed Web of Science ®Google Scholar
• Mitchell CH, Peterson-Yantorno K, Carre DA, et al. A3 adenosine receptors regulate Cl− channels of nonpigmented ciliary epithelial cells. Am J Physiol 1999;276:C659-66
   PubMed Web of Science ®Google Scholar
• Husain S, Shearer TW, Crosson CE. Mechanisms linking adenosine A1 receptors and extracellular signal-regulated kinase 1/2 activation in human trabecular meshwork cells. J Pharmacol Exp Ther 2007;320:258-65
   PubMed Web of Science ®Google Scholar
• Shearer TW, Crosson CE. Adenosine A1 receptor modulation of MMP-2 secretion by trabecular meshwork cells. Invest Ophthalmol Vis Sci 2002;43:3016-20
   PubMed Web of Science ®Google Scholar
• Crosson CE. Adenosine receptor activation modulates intraocular pressure in rabbits. J Pharmacol Exp Ther 1995;273:320-6
   PubMed Web of Science ®Google Scholar
• Avila MY, Stone RA, Civan MM. A(1)-, A(2A)- and A(3)-subtype adenosine receptors modulate intraocular pressure in the mouse. Br J Pharmacol 2001;134:241-5
   PubMed Web of Science ®Google Scholar
• Crosson CE. Ocular hypotensive activity of the adenosine agonist (R)-phenylisopropyladenosine in rabbits. Curr Eye Res 1992;11:453-8
   PubMed Web of Science ®Google Scholar
• Konno T, Murakami A, Uchibori T, et al. Involvement of adenosine A2a receptor in intraocular pressure decrease induced by 2-(1-octyn-1-yl)adenosine or 2-(6-cyano-1-hexyn-1-yl)adenosine. J Pharmacol Sci 2005;97:501-9
   PubMed Web of Science ®Google Scholar
• Karl MO, Fleischhauer JC, Stamer WD, et al. Differential P1-purinergic modulation of human schlemm's canal inner-wall cells. Am J Physiol 2005;288:C784-94
   Google Scholar
• Fleischhauer JC, Mitchell CH, Stamer WD, et al. Common actions of adenosine receptor agonists in modulating human trabecular meshwork cell transport. J Membr Biol 2003;193:121-36
   Web of Science ®Google Scholar
• Henderson R, Schertler GF. The structure of bacteriorhodopsin and its relevance to the visual opsins and other seven-helix G-protein coupled receptors. Philos Trans R Soc Lond B Biol Sci 1990;326:379-89
   PubMedGoogle Scholar
• Fredholm BB, Arslan G, Halldner L, et al. Adenosine receptor signalling in vivo and in vitro. Drug Dev Res 2001;52:274-82
   Google Scholar
• Gether U. Uncovering molecular mechanisms involved in activation of G protein-coupled receptors. Endocr Rev 2000;21(1):90-113
   PubMed Web of Science ®Google Scholar
• Watkins PA, Burns DL, Kanaho Y, et al. ADP-ribosylation of transducin by pertussis toxin. J Biol Chem 1985;260(25):13478-82
   PubMedGoogle Scholar
• Northup JK, Sternweis PC, Smigel MD, et al. Purification of the regulatory component of adenylate cyclase. Proc Natl Acad Sci USA 1980;77(11):6516-20
   PubMedGoogle Scholar
• Gudermann T, Schöneberg T, Schultz G. Functional and structural complexity of signal transduction via G-protein-coupled receptors. Annu Rev Neurosci 1997;20:399-427
   PubMedGoogle Scholar
• Freissmuth M, Selzer E, Schütz W. Interactions of purified bovine brain A1-adenosine receptors with G-proteins. Reciprocal modulation of agonist and antagonist binding. Biochem J 1991;275:651-6
   PubMed Web of Science ®Google Scholar
• Akbar M, Okajima F, Tomura H, et al. A single species of A1 adenosine receptor expressed in chinese hamster ovary cells not only inhibits cAMP accumulation but also stimulates phospholipase C and arachidonate release. Mol Pharmacol 1994;45(5):1036-42
   PubMedGoogle Scholar
• Palmer TM, Gettys TW, Stiles GL. Differential interaction with and regulation of multiple G-proteins by the rat A3 adenosine receptors. J Biol Chem 1995;270:16895-902
   PubMedGoogle Scholar
• Muanprasat C, Chatsudthipong V. Cholera: pathophysiology and emerging therapeutic targets. Future Med Chem 2013;5(7):781-98
   PubMedGoogle Scholar
• Fredholm BB, Arslan G, Kull B, et al. Adenosine P1 receptor signalling. Drug Dev Res 1996;39:262-8
   Google Scholar
• Klinger M, Freissmuth M, Nanoff C. Adenosine receptors: G protein-mediated signalling and the role of accessory proteins. Cell Signal 2002;14:99-108
   PubMed Web of Science ®Google Scholar
• Hanoune J, Defer N. Regulation and role of adenylyl cyclase isoforms. Annu Rev Pharmacol Toxicol 2001;41:145-74
   PubMed Web of Science ®Google Scholar
• Mayr B, Montminy M. Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol 2001;2(8):599-609
   PubMed Web of Science ®Google Scholar
• Dickenson JM, Hill SJ. Involvement of G-protein betagamma subunits in coupling the adenosine A1 receptor to phospholipase C in transfected CHO cells. Eur J Pharmacol 1998;355(1):85-93
   PubMedGoogle Scholar
• Vanhaesebroeck B, Alessi DR. The PI3K-PDK1 connection: more than just a road to PKB. Biochem J 2000;346:561-76
   PubMed Web of Science ®Google Scholar
• Toker A. Protein kinases as mediators of phosphoinositide 3-kinase signalling. Mol Pharmacol 2000;57(4):652-8
   PubMedGoogle Scholar
• Gsandtner I, Charalambous C, Stefan E, et al. Heterotrimeric G protein-independent signaling of a G protein-coupled receptor. Direct binding of ARNO/cytohesin-2 to the carboxyl terminus of the A2A adenosine receptor is necessary for sustained activation of the ERK/MAP kinase pathway. J Biol Chem 2005;280(36):31898-905
   PubMedGoogle Scholar
• Widmann C, Gibson S, Jarpe MB, et al. Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol Rev 1999;79:143-80
   PubMed Web of Science ®Google Scholar
• Chen Z, Gibson TB, Robinson F, et al. MAPK kinases. Chem Rev 2001;101:2449-76
   PubMed Web of Science ®Google Scholar
• Kyriakis JM, Avruch J. Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update. Physiol Rev 2012;92(2):689-737
   PubMed Web of Science ®Google Scholar
• Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2000;103(2):211-25
   PubMed Web of Science ®Google Scholar
• Enserink JM, Christensen AE, de Rooij J, et al. A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK. Nat Cell Biol 2002;4(11):901-6
   PubMedGoogle Scholar
• Quilliam LA, Mueller H, Bohl BP, et al. Rap1A is a substrate for cyclic AMP-dependent protein kinase in human neutrophils. J Immunol 1991;147(5):1628-35
   PubMedGoogle Scholar
• Vossler MR, Yao H, York RD, et al. cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell 1997;89(1):73-82
   PubMed Web of Science ®Google Scholar
• Kitayama H, Sugimoto Y, Matsuzaki T, et al. A ras-related gene with transformation suppressor activity. Cell 1989;56(1):77-84
   PubMedGoogle Scholar
• Schmitt JM, Stork PJ. PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1. Mol Cell 2002;9(1):85-94
   PubMedGoogle Scholar
• York RD, Yao H, Dillon T, et al. Rap1 mediates sustained MAP kinase activation induced by nerve growth factor. Nature 1998;392(6676):622-6
   PubMedGoogle Scholar
• Houslay MD, Kolch W. Cell-type specific integration of cross-talk between extracellular signal-regulated kinase and cAMP signaling. Mol Pharmacol 2000;58(4):659-68
   PubMedGoogle Scholar
• Schmitt JM, Stork PJ. Beta 2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein rap1 and the serine/threonine kinase B-Raf. J Biol Chem 2000;275(33):25342-50
   PubMedGoogle Scholar
• Schmitt JM, Stork PJ. Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1. Mol Cell Biol 2001;21(11):3671-83
   PubMedGoogle Scholar
• Cook SJ, McCormick F. Inhibition by cAMP of Ras-dependent activation of Raf. Science 1993;262(5136):1069-72
   PubMedGoogle Scholar
• Kawasaki H, Springett GM, Mochizuki N, et al. A family of cAMP-binding proteins that directly activate Rap1. Science 1998;282(5397):2275-9
   PubMed Web of Science ®Google Scholar
• de Rooij J, Zwartkruis FJ, Verheijen MH, et al. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature 1998;396(6710):474-7
   PubMed Web of Science ®Google Scholar
• Birnbaumer L. Receptor-to-effector signaling through G proteins: roles for beta gamma dimers as well as alpha subunits. Cell 1992;71(7):1069-72
   PubMedGoogle Scholar
• Dikic I, Tokiwa G, Lev S, et al. A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature 1996;383(6600):547-50
   PubMedGoogle Scholar
• Della Rocca GJ, van Biesen T, Daaka Y, et al. Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase. J Biol Chem 1997;272(31):19125-32
   PubMedGoogle Scholar
• Blaukat A, Ivankovic-Dikic I, Grönroos E, et al. Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades. J Biol Chem 1999;274(21):14893-901
   PubMedGoogle Scholar
• Burgering BM, Bos JL. Regulation of Ras-mediated signalling: more than one way to skin a cat. Trends Biochem Sci 1995;20(1):18-22
   PubMed Web of Science ®Google Scholar
• Mattingly RR, Macara IG. Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits. Nature 1996;382(6588):268-72
   PubMedGoogle Scholar
• Lopez-Ilasaca M, Crespo P, Pellici PG, et al. Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma. Science 1997;275(5298):394-7
   PubMedGoogle Scholar
• Murga C, Fukuhara S, Gutkind JS. A novel role for phosphatidylinositol 3-kinase beta in signaling from G protein-coupled receptors to Akt. J Biol Chem 2000;275(16):12069-73
   PubMedGoogle Scholar
• Pleiman CM, Hertz WM, Cambier JC. Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit. Science 1994;263(5153):1609-12
   PubMedGoogle Scholar
• Cussac D, Newman-Tancredi A, Pasteau V, et al. Human dopamine D(3) receptors mediate mitogen-activated protein kinase activation via a phosphatidylinositol 3-kinase and an atypical protein kinase C-dependent mechanism. Mol Pharmacol 1999;56(5):1025-30
   PubMedGoogle Scholar
• Takeda H, Matozaki T, Takada T, et al. PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor. EMBO J 1999;18(2):386-95
   PubMed Web of Science ®Google Scholar
• Fukuhara S, Chikumi H, Gutkind JS. RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho? Oncogene 2001;20(13):1661-8
   PubMed Web of Science ®Google Scholar
• Pomerance M, Abdullah HB, Kamerji S, et al. Thyroid-stimulating hormone and cyclic AMP activate p38 mitogen-activated protein kinase cascade. Involvement of protein kinase A, rac1, and reactive oxygen species. J Biol Chem 2000;275(51):40539-46
   PubMedGoogle Scholar
• Gutkind JS. Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors. Sci STKE 2000;2000(40):re1
   PubMedGoogle Scholar
• Marinissen MJ, Gutkind JS. G-protein-coupled receptors and signaling networks: emerging paradigms. Trends Pharmacol Sci 2001;22(7):368-76
   PubMed Web of Science ®Google Scholar
• Zhong Y, Yang Z, Huang WC, et al. Adenosine, adenosine receptors and glaucoma: an updated overview. Biochim Biophys Acta 2013;1830(4):2882-90
   PubMed Web of Science ®Google Scholar
• Crosson CE, Gray T. Characterization of ocular hypertension induced by adenosine agonists. Invest Ophthalmol Vis Sci 1996;37:1833-9
   PubMed Web of Science ®Google Scholar
• Chen J, Runyan SA, Robinson MR. Novel ocular antihypertensive compounds in clinical trials. Clin Ophthalmol 2011;5:667-77
   PubMedGoogle Scholar
• Crosson CE. Intraocular pressure responses to the adenosine agonist cyclohexyladenosine: evidence for a dual mechanism of action. Invest Ophthalmol Vis Sci 2001;42:1837-40
   PubMed Web of Science ®Google Scholar
• Crosson CE, Gray T. Response to prejunctional adenosine receptors is dependent on stimulus frequency. Curr Eye Res 1997;16:359-64
   PubMed Web of Science ®Google Scholar
• Wax M, Sanghavi DM, Lee CH, et al. Purinergic receptors in ocular ciliary epithelial cells. Exp Eye Res 1993;57:89-95
   PubMed Web of Science ®Google Scholar
• Seidel MG, Klinger M, Freissmuth M, et al. Activation of mitogen-activated protein kinase by the A(2A)-adenosine receptor via a rap1-dependent and via a p21(ras)-dependent pathway. J Biol Chem 1999;274(36):25833-41
   PubMedGoogle Scholar
• Klinger M, Kudlacek O, Seidel MG, et al. MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases. J Biol Chem 2002;277(36):32490-7
   PubMedGoogle Scholar
• Chan ESL, Liu H, Fernandez P, et al. Adenosine A2A receptors promote collagen production by a Fli1- and CTGF-mediated mechanism. Arthritis Res Therap 2013;15(3):R58
   Google Scholar
• Gu J, Liu X, Wang QX, et al. Angiotensin II increases CTGF expression via MAPKs/TGF-β1/TRAF6 pathway in atrial fibroblasts. Exp Cell Res 2012;318(16):2105-15
   PubMedGoogle Scholar
• Olanrewaju HA, Gafurov BS, Lieberman EM. Involvement of K+ channels in adenosine A2A and A2B receptor-mediated hyperpolarization of porcine coronary artery endothelial cells. J Cardiovasc Pharmacol 2002;40(1):43-9
   PubMedGoogle Scholar
• Stumpff F, Strauss O, Boxberger M, et al. Characterization of maxi-K-channels in bovine trabecular meshwork and their activation by cyclic guanosine monophosphate. Invest Ophthalmol Vis Sci 1997;38(9):1883-92
   PubMedGoogle Scholar
• Nara M, Dhulipala PDK, Wang YX, et al. Reconstitution of β-adrenergic modulation of large conductance, calcium-activated potassium (maxi-K) channels in xenopusoocytes: identification of the cAMP-dependent protein kinase phosphorylation site. J Biol Chem 1998;273(24):14920-4
   PubMedGoogle Scholar
• Stumpff F, Wiederholt M. Regulation of trabecular meshwork contractility. Ophthalmologica 2000;214:33-53
   PubMed Web of Science ®Google Scholar
• Mitchell CH, Peterson-Yantorno K, Carré DA, et al. A3 adenosine receptors regulate Cl- channels of nonpigmented ciliary epithelial cells. Am J Physiol 1999;276(3 Pt 1):C659-66
   Google Scholar
• Prendergast GC, Rane N. Farnesyltransferase inhibitors: mechanism and applications. Expert Opin Investig Drugs 2001;10(12):2105-16
   PubMed Web of Science ®Google Scholar
• Inoue T, Tanihara H. Rho-associated kinase inhibitors: a novel glaucoma therapy. Prog Ret Eye Res 2013;37:1-12
   PubMed Web of Science ®Google Scholar