243
Views
2
CrossRef citations to date
0
Altmetric
Reviews

Antithrombotic therapy: new areas to understand efficacy and bleeding

, MD & , MD
Pages 1427-1434 | Published online: 27 Oct 2014

Bibliography

  • Mackman N. Triggers, targets and treatments for thrombosis. Nature 2008;451(7181):914-18
  • Wisler JW, Becker RC. Emerging paradigms in arterial thrombosis. J Thromb Thrombolysis 2014;37(1):4-11
  • Fuchs TA, Kremer Hovinga JA, Schatzberg D, et al. Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies. Blood 2012;120(6):1157-64
  • Jahr S, Hentze H, Englisch S, et al. DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res 2001;61(4):1659-65
  • Brinkmann V, Reichard U, Goosmann C, et al. Neutrophil extracellular traps kill bacteria. Science 2004;303(5663):1532-5
  • Stroun M, Lyautey J, Lederrey C, et al. About the possible origin and mechanism of circulating DNA apoptosis and active DNA release. Clin Chim Acta 2001;313(1-2):139-42
  • Franklin BS, Vitorino BL, Coelho HC, et al. Plasma circulating nucleic acids levels increase according to the morbidity of plasmodium vivax malaria. PLoS One 2011;6(5):e19842
  • Nakazawa F, Kannemeier C, Shibamiya A, et al. Extracellular rna is a natural cofactor for the (auto-)activation of factor vii-activating protease (fsap). Biochem J 2005;385(Pt 3):831-8
  • Kannemeier C, Shibamiya A, Nakazawa F, et al. Extracellular rna constitutes a natural procoagulant cofactor in blood coagulation. Proc Natl Acad Sci USA 2007;104(15):6388-93
  • Swystun LL, Mukherjee S, Liaw PC. Breast cancer chemotherapy induces the release of cell-free DNA, a novel procoagulant stimulus. J Thromb Haemost 2011;9(11):2313-21
  • Chang CP, Chia RH, Wu TL, et al. Elevated cell-free serum DNA detected in patients with myocardial infarction. Clin Chim Acta 2003;327(1-2):95-101
  • Rainer TH, Wong LK, Lam W, et al. Prognostic use of circulating plasma nucleic acid concentrations in patients with acute stroke. Clin Chem 2003;49(4):562-9
  • Xu J, Zhang X, Pelayo R, et al. Extracellular histones are major mediators of death in sepsis. Nat Med 2009;15(11):1318-21
  • Lo YM, Rainer TH, Chan LY, et al. Plasma DNA as a prognostic marker in trauma patients. Clin Chem 2000;46(3):319-23
  • Lo YM, Chan LY, Lo KW, et al. Quantitative analysis of cell-free epstein-barr virus DNA in plasma of patients with nasopharyngeal carcinoma. Cancer Res 1999;59(6):1188-91
  • Pornthanakasem W, Shotelersuk K, Termrungruanglert W, et al. Human papillomavirus DNA in plasma of patients with cervical cancer. BMC Cancer 2001;1:2
  • Sorenson GD, Pribish DM, Valone FH, et al. Soluble normal and mutated DNA sequences from single-copy genes in human blood. Cancer Epidemiol Biomarkers Prev 1994;3(1):67-71
  • Vasioukhin V, Anker P, Maurice P, et al. Point mutations of the n-ras gene in the blood plasma DNA of patients with myelodysplastic syndrome or acute myelogenous leukaemia. Br J Haematol 1994;86(4):774-9
  • Holdenrieder S, Stieber P. Clinical use of circulating nucleosomes. Crit Rev Clin Lab Sci 2009;46(1):1-24
  • Semeraro F, Ammollo CT, Morrissey JH, et al. Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet tlr2 and tlr4. Blood 2011;118(7):1952-61
  • Remijsen Q, Vanden Berghe T, Wirawan E, et al. Neutrophil extracellular trap cell death requires both autophagy and superoxide generation. Cell Res 2011;21(2):290-304
  • Steinberg BE, Grinstein S. Unconventional roles of the nadph oxidase: signaling, ion homeostasis, and cell death. Sci STKE 2007;2007(379):pe11
  • AbiAbdallah DS, Denkers EY. Neutrophils cast extracellular traps in response to protozoan parasites. Front Immunol 2012;3:382
  • Brinkmann V, Zychlinsky A. Beneficial suicide: why neutrophils die to make nets. Nat Rev Microbiol 2007;5(8):577-82
  • Fuchs TA, Abed U, Goosmann C, et al. Novel cell death program leads to neutrophil extracellular traps. J Cell Biol 2007;176(2):231-41
  • Papayannopoulos V, Zychlinsky A. Nets: a new strategy for using old weapons. Trends Immunol 2009;30(11):513-21
  • Wang Y, Li M, Stadler S, et al. Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol 2009;184(2):205-13
  • vonBruhl ML, Stark K, Steinhart A, et al. Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. J Exp Med 2012;209(4):819-35
  • Fuchs TA, Brill A, Duerschmied D, et al. Extracellular DNA traps promote thrombosis. Proc Natl Acad Sci USA 2010;107(36):15880-5
  • Clark SR, Ma AC, Tavener SA, et al. Platelet tlr4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med 2007;13(4):463-9
  • Gupta AK, Joshi MB, Philippova M, et al. Activated endothelial cells induce neutrophil extracellular traps and are susceptible to netosis-mediated cell death. FEBS Lett 2010;584(14):3193-7
  • Massberg S, Grahl L, von Bruehl ML, et al. Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases. Nat Med 2010;16(8):887-96
  • Saffarzadeh M, Juenemann C, Queisser MA, et al. Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones. PLoS One 2012;7(2):e32366
  • Okrent DG, Lichtenstein AK, Ganz T. Direct cytotoxicity of polymorphonuclear leukocyte granule proteins to human lung-derived cells and endothelial cells. Am Rev Respir Dis 1990;141(1):179-85
  • Pereira LF, Marco FM, Boimorto R, et al. Histones interact with anionic phospholipids with high avidity; its relevance for the binding of histone-antihistone immune complexes. Clin Exp Immunol 1994;97(2):175-80
  • Kleine TJ, Gladfelter A, Lewis PN, Lewis SA. Histone-induced damage of a mammalian epithelium: the conductive effect. Am J Physiol 1995;268(5 Pt 1):C1114-25
  • Sporn LA, Marder VJ, Wagner DD. Inducible secretion of large, biologically potent von willebrand factor multimers. Cell 1986;46(2):185-90
  • Fuchs TA, Bhandari AA, Wagner DD. Histones induce rapid and profound thrombocytopenia in mice. Blood 2011;118(13):3708-14
  • Watson K, Gooderham NJ, Davies DS, Edwards RJ. Nucleosomes bind to cell surface proteoglycans. J Biol Chem 1999;274(31):21707-13
  • Clejan L, Menahem H. Binding of deoxyribonucleic acid to the surface of human platelets. Acta Haematol 1977;58(2):84-8
  • Dorsch CA. Binding of single-strand DNA to human platelets. Thromb Res 1981;24(1-2):119-29
  • Higuchi DA, Wun TC, Likert KM, Broze GJ Jr. The effect of leukocyte elastase on tissue factor pathway inhibitor. Blood 1992;79(7):1712-19
  • Borissoff JI, Joosen IA, Versteylen MO, et al. Elevated levels of circulating DNA and chromatin are independently associated with severe coronary atherosclerosis and a prothrombotic state. Arterioscler Thromb Vasc Biol 2013;33(8):2032-40
  • de Boer OJ, Li X, Teeling P, et al. Neutrophils, neutrophil extracellular traps and interleukin-17 associate with the organisation of thrombi in acute myocardial infarction. Thromb Haemost 2013;109(2):290-7
  • Boulaftali Y, Hess PR, Getz TM, et al. Platelet itam signaling is critical for vascular integrity in inflammation. J Clin Invest 2013;123(2):908-16
  • Ho-Tin-Noe B, Demers M, Wagner DD. How platelets safeguard vascular integrity. J Thromb Haemost 2011;9(Suppl 1):56-65
  • Hottz ED, Lopes JF, Freitas C, et al. Platelets mediate increased endothelium permeability in dengue through nlrp3-inflammasome activation. Blood 2013;122(20):3405-14
  • Bulut D, Becker V, Mugge A. Acetylsalicylate reduces endothelial and platelet-derived microparticles in patients with coronary artery disease. Can J Physiol Pharmacol 2011;89(4):239-44
  • Mause SF, Ritzel E, Liehn EA, et al. Platelet microparticles enhance the vasoregenerative potential of angiogenic early outgrowth cells after vascular injury. Circulation 2010;122(5):495-506
  • Chatterjee M, Gawaz M. Platelet-derived cxcl12 (sdf-1alpha): basic mechanisms and clinical implications. J Thromb Haemost 2013;11(11):1954-67
  • Risitano A, Beaulieu LM, Vitseva O, Freedman JE. Platelets and platelet-like particles mediate intercellular rna transfer. Blood 2012;119(26):6288-95
  • Cecchetti L, Tolley ND, Michetti N, et al. Megakaryocytes differentially sort mrnas for matrix metalloproteinases and their inhibitors into platelets: a mechanism for regulating synthetic events. Blood 2011;118(7):1903-11
  • Voora D, Cyr D, Lucas J, et al. Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events. J Am Coll Cardiol 2013;62(14):1267-76
  • Jain S, Pitoc GA, Holl EK, et al. Nucleic acid scavengers inhibit thrombosis without increasing bleeding. Proc Natl Acad Sci USA 2012;109(32):12938-43
  • Brill A, Fuchs TA, Savchenko AS, et al. Neutrophil extracellular traps promote deep vein thrombosis in mice. J Thromb Haemost 2012;10(1):136-44

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.