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Review

ADAM33: a novel therapeutic target for asthma

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Pages 485-494 | Published online: 02 Mar 2005

Bibliography

  • GLOBAL INITIATIVE FOR ASTHMA: Global strategy for asthma management and prevention. National Institutes of Health, National Heart, Lung and Blood Institute (2002).
  • SHEFFER A: Global Initiative for asthma. NHLBI/WHO Workshop report. National Heart Lung and Blood Institute (1995).
  • CARROLL N, LEHMANN E, BARRET J et al.: Variability of airway structure and inflammation in normal subjects and in cases of nonfatal and fatal asthma. Pathol Res. Pratt (1996) 192:238–248.
  • JUNIPER EF, KLINE PA, VANZIELEGHEM MA et al.: Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics. Am. Rev Respir: Dis. (1990) 142:832–836.
  • JAMES AL, PARE PD, HOGG JC: The mechanics of airway narrowing in asthma. Am. Rev Respir Dis. (1989) 139:242–246.
  • WIGGS BR, MORENO R, HOGG JC, HILLIAM C, PARE PD: A model of the mechanics of airway narrowing. Appl. Physic] (1990) 69:849–860.
  • LAMBERT RK, WIGGS BR, KUWANO K, HOGG JC, PARE PD: Functional significance of increased airway smooth muscle in asthma and COPD. Appl. Physic] (1993) 74:2771–2781.
  • FREDBERG JJ: Airway smooth muscle in asthma: flirting with disaster. Eur. Respir. (1998) 12:1252–1256.
  • KLINKE DJ, LEWIS AK, WONG S-P, STOKES CL: Airway hyperresponsiveness: exploration of a mechanism using a dynamic, computer-based model of asthma. Am. Rev*: Grit. Care Med. (2001) 163:A832.
  • TOWNLEY RG, BEWTRA A, WILSON AF et al: Segregation analysis of bronchial response to methacholine inhalation challenge in families with and without asthma. I Allergy Chu. Immune] (1986) 77:101–107.
  • HOPP RJ, BEWTRA AK, BIVEN R, NAIR NM, TOWNLEY RG: Bronchial reactivity pattern in nonasthmatic parents of asthmatics. Ann. Allergy (1988) 61:184–186.
  • KONIG P, GODFREY S: Prevalence of exercise-induced bronchial lability in families of children with asthma. Arch. Dis. Child (1973) 48:513–518.
  • LONGO G, STRINATI R, POLI F, FUMI F: Genetic factors in nonspecific bronchial hyperreactivity. An epidemiologic study. Am. j Dis. Child. (1987) 141:331–334.
  • DAVIES DE, WICKS J, POWELL RM, PUDDICOMBE SM, HOLGATE ST: Airway remodeling in asthma: new insights. Allergy Chu. Immune] (2003) 111:215–225.
  • ••Comprehensive review of airwayremodelling in asthma.
  • PAYNE DN, ROGERS AV, ADELROTH E et al.: Early thickening of the reticular basement membrane in children with difficult asthma. Am. j Respir: Grit. Care Med. (2003) 167:78–82.
  • POHUNEK P, ROCHE WR, TARZIKOVA J, KURDMANN J, WARNER JO: Eosinophioic inflammation in the bronchial mucosa in children with bronchial asthma. Eur. Respir. j (2000) 11:S160.
  • DEZATEUX C, STOCKS J: Lung development and early origins of childhood respiratory illness. Br Med. Bull. (1997) 53:40–57.
  • PALMER LJ, RYE PJ, GIBSON NA et al:Airway responsiveness in early infancy predicts asthma, lung function, and respiratory symptoms by school age. Am. J Respir Grit. Care Med. (2001) 163:37–42.
  • BRYAN SA, O'CONNOR BJ, MATTI S et al: Effects of recombinant human interleukin-12 on eosinophils, airway hyperresponsiveness, and the late asthmatic response. Lancet (2000) 356:2149–2153.
  • PRETOLANI M, GOLDMAN M: IL-10: a potential therapy for allergic inflammation? Immunol. Today (1997) 18:277–280.
  • FLOOD-PAGE PT, MENZIES-GOW AN, KAY AB, ROBINSON DS: Eosinophifs role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. Am. j Respir. Grit. Care Med. (2003) 167:199–204.
  • LECKIE MJ, TEN BRINKE A, KHAN J et al: Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet (2000) 356:2144–2148.
  • BORISH LC, NELSON HS, LANZ MJ et al: Interleukin-4 receptor in moderate atopic asthma. A Phase I/II randomized, placebo-controlled trial. Am. I Respir Grit. Care Med. (1999) 160:1816–1823.
  • LIN K, ATEEQ HS, HSIUNG SH etal.: Selective, tight-binding inhibitors of integrin a4131 that inhibit allergic airway responses. Med. Chem. (1999) 42:920–934.
  • CRETICOS PS, REED CE, NORMAN PS et al: Ragweed immunotherapy in adult asthma. N Engl. j Med. (1996) 334:501–506.
  • REDINGTON AE, HARDINGE FM, MADDEN J, HOLGATE ST, HOWARTH PH: Cyclosporin A treatment and airways inflammation in corticosteroid-dependent asthma. Allergy (1998) 53:94–98.
  • MILGROM H, FICK RB Jr, SU JQ et al:Treatment of allergic asthma with monoclonal anti-IgE antibody. rhuMAb-E25 Study Group. N Engl. j Med. (1999) 341:1966–1973.
  • DUFFY DL, MARTIN NG, BATTISTUTTA D, HOPPER JL, MATHEWS JD: Genetics of asthma and hay fever in Australian twins. Am. Rev Respir Dis. (1990) 142:1351–1358.
  • JENKINS MA, HOPPER JL, GILES GG:Regressive logistic modeling of familial aggregation for asthma in 7,394 population-based nuclear families. Genet. Epidemiol (1997) 14:317–332.
  • HOLLOWAY JW, JONGEPIER H, BEGHE B et al.: The genetics of asthma. Eur Respir. Mono. (2003) 8:26–56.
  • •Review of current knowledge on the genetic basis of asthma.
  • WANG Z, CHEN C, NIU T et al: Association of asthma with 13(2)-adrenergic receptor gene polymorphism and cigarette smoking. Am. J. Respir Grit. Care Med. (2001) 163:1404–1409.
  • HORIKAWA Y, ODA N, COX NJ et al.: Genetic variation in the gene encoding calpain-10 is associated with Type 2 diabetes mellitus. Nat. Genet. (2000) 26:163–175.
  • HUGOT JP, CHAMAILLARD M, ZOUALI H et al.: Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature (2001) 411:599–603.
  • VAN EERDEWEGH P, LITTLE RD, DUPUIS J et al.: Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature (2002) 418:426–430
  • ••Identification of ADAM33 as an asthmasusceptibility gene.
  • LANDER E, KRUGLYAK L: Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat. Genet. (1995) 11:241–247.
  • COOKSON WO, UBHI B, LAWRENCE R et al: Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci. Nat. Genet. (2001) 27:372–373.
  • XU J, MEYERS DA, OBER C et al: Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three US populations: collaborative study on the genetics of asthma. Am. j Hum. Genet. (2001) 68:1437–1446.
  • DE SANCTIS GT, MERCHANT M, BEIER DR et al: Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice. Nat. Genet. (1995) 11:150–154.
  • YOSHINAKA T, NISHII K, YAMADA K et al: Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity. Gene (2002) 282:227–236.
  • •Identification of the human ADAM33 gene.
  • HOWARD TD, MEYERS DA, AMPLEFORD EA etal.: Association of ADAM33 with asthma and associated phenotypes in ethnically diverse populations. Am. j Hum. Genet. (2002) 71(4 Suppl.):A1861.
  • GUNN TM, AZARANI A, KIM PH et al: Identification and preliminary characterization of mouse Adam33. BMC Genet. (2002) 3:2.
  • BLACK RA, WHITE JM: ADAMs: focus on the protease domain. Curr. Opin Cell Biol. (1998) 10:654–659.
  • PRIMAKOFF P, MYLES DG: The ADAM gene family: surface proteins with adhesion and protease activity. Trends Genet. (2000) 16:83–87.
  • VAN WART HE, BIRKEDAL-HANSEN H: The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family. Proc. Nat] Acad. ScL USA (1990) 87:5578–5582.
  • LOECHEL F, OVERGAARD MT, OXVIG C, ALBRECHTSEN R, WEWER UM: Regulation of human ADAM 12 protease by the prodomain. Evidence for a functional cysteine switch. Biol. Chem. (1999) 274:13427–13433.
  • BLACK RA, RAUCH CT, KOZLOSKY CJ et al.: A metalloproteinase disintegrin that releases tumour-necrosis factor-a from cells. Nature (1997) 385:729–733.
  • HOWARD L, ZHENG Y, HORROCKS M, MACIEWICZ RA, BLOBEL C: Catalytic activity of ADAM28. FEBS Lett. (2001) 498:82–86.
  • GARLISI CG, ZOU J, DEVITO KE et al.: Human ADAM33: protein maturation and localization. Biochem. Biophys. Res. Commun. (2003) 301:35–43.
  • PAN D, RUBIN GM: Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila 492 and vertebrate neurogenesis. Cell (1997) 90:271–280.
  • SHIRAKABE K, WAKATSUKI S, KURISAKI T, FUJISAWA-SEHARA A: Roles of Melain 3/ADAM19 in the processing of neuregulin. J. Biol. Chem. (2001) 276:9352–9358.
  • BRIDGES LC, TANI PH, HANSON KR et al.: The lymphocyte metalloprotease MDC-L (ADAM 28) is a ligand for the integrin a4131. _J. Biol. Chem. (2002) 277:3784–3792.
  • ETO K, PUZON-MCLAUGHLIN W SHEPPARD D et al: RGD-independent binding of integrin a9l31 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction. J. Biol. Chem. (2000) 275:34922–34930.
  • IBA K, ALBRECHTSEN R, GILPIN B et al.: The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to 131 integrin-dependent cell spreading. J. Cell Biol. (2000) 149:1143–1156.
  • HUOVILA AE ALMEIDA EA, WHITE JM: ADAMs and cell fusion. Curr. Opin. Cell Biol. (1996) 8:692–699.
  • KANG Q, CAO Y, ZOLKIEWSKA A: Metalloprotease-disintegrin ADAM 12 binds to the 5H3 domain of Src and activates Src tyrosine kinase in C2C12 cells. Biochem. J. (2000) 352(3):883–892.
  • HUANG L, FENG L, YANG L et al: Screen and identification of proteins interacting with ADAM19 cytoplasmic tail. Mai Biol. Rep. (2002) 29:317–323.
  • ASAKURA M, KITAKAZE M, TAKASHIMA S etal.: Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy. Nat. Med. (2002) 8:35–40.
  • •Study showing role of GPCRs in ADAM activation and the role of ADAM12 in cardiac hypertrophy.
  • MOHAN MJ, SEATON T, MITCHELL J et al.: The tumor necrosis factor-a converting enzyme (TACE): a unique metalloproteinase with highly defined substrate selectivity. Biochemistry (Mosc) (2002) 41:9462–9469.
  • MOSS ML, WHITE JM, LAMBERT MH, ANDREWS RC: TACE and other ADAM proteases as targets for drug discovery. Drug Discov. Today (2001) 6:417–426.
  • HAMILTON LM, TORRES-LOZANO C, PUDDICOMBE SM etal.: The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma. Clin. Exp. Allergy (2003) 33:233–240.
  • TAKEYAMA K, FAHY JV, NADEL JA: Relationship of epidermal growth factor receptors to goblet cell production in human bronchi. Am. J. Respir. Grit. Care Med. (2001) 163:511–516.
  • YAN Y, SHIRAKABE K, WERB Z: The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptors. J. Cell Biol. (2002) 158:221–226.
  • ASAI M, HATTORI C, SZABO B et al: Putative function of ADAM9, ADAM10, and ADAM17 as APP a-secretase. Biochem. Biophys. Res. Commun. (2003) 301:231–235.
  • TANG BL: ADAMTS: a novel family of extracellular matrix proteases. Int. J. Biochem. Cell Biol. (2001) 33:33–44.
  • LEVY GG, NICHOLS WC, LIAN EC etal.: Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature (2001) 413:488–494.
  • KOKAME K, MATSUMOTO M, SOEJIMA K etal.: Mutations and common polymorphisms in ADAIVITS13 gene responsible for von Willebrand factor-cleaving protease activity. Proc Natl. Acad. Sci. USA (2002) 99:11902–11907.
  • COLIGE A, SIERON AL, LI SW et al: Human Ehlers-Danlos syndrome Type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene. Am. J. Hum. Genet. (1999) 65:308–317.
  • HOLGATE ST, LACKIE PM, HOWARTH PH et al.: Activation of the epithelial mesenchymal trophic unit in the pathogenesis of asthma. Int. Arch. Allergy Immunol (2001) 124:253–258.
  • RICHTER A, PUDDICOMBE SM, LORDAN JL et al.: The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma. Am. J. Respir. Cell Mal Biol. (2001) 25:385–391.
  • ZHANG S, SMARTT H, HOLGATE ST, ROCHE WR: Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: an in vitro co-culture model of airway remodeling in asthma. Lab. Invest. (1999) 79:395–405.
  • PUDDICOMBE SM, POLOSA R, RICHTER A et al: Involvement of the epidermal growth factor receptor in epithelial repair in asthma. FASEB J. (2000) 14:1362–1374.
  • JOHNSON PR, ROTH M, TAMM M et al.: Airway smooth muscle cell proliferation is increased in asthma. Am. J. Respir Grit. Care Med. (2001) 164:474–477.
  • POWELL RM, WICKS J, HOLLOWAY JW, DAVIES DE, HOLGATE ST: Identification and quantification of novel splice variants of ADAM33 reveal distinct tissue expression profiles. Am. J. Respir. Grit. Care Med. (2003) 167(7):A440.
  • GILPIN BJ, LOECHEL F, MATTEI MG et al.: A novel, secreted form of human ADAM 12 (meltrin a) provokes myogenesis in vivo. J. Biol. Chem. (1998) 273:157–166.
  • •Study showing how ADAMs can play a role in myogenesis.
  • OLSON GE, WINFREY VE MATRISIAN PE, NAGDAS SK, HOFFMAN LH: Blastocyst-dependent upregulation of metalloproteinasehlisintegrin MDC9 expression in rabbit endometrium. Cell Tissue Res. (1998) 293:489–498.
  • NAMBA K, NISHIO M, MORI K et al:Involvement of ADAM9 in multinucleated giant cell formation of blood monocytes. Cell. Immunol (2001) 213:104–113.
  • OGURA Y, BONEN DK, INOHARA N et al: A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature (2001) 411:603–606.
  • PROKUNINA L, CASTILLEJO-LOPEZ C, OBERG F et al: A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat. Genet. (2002) 32:666–669.

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