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Review

Why is the Plasmodium falciparum hexose transporter a promising new drug target?

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Pages 593-602 | Published online: 02 Mar 2005

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  • ••One of two papers that provide the firststructural insight for the major facilitator superfamily of transporters, for which crystal structures have been hitherto lacking. The lactose permease has been one of the most intensively studied transporters and will provide great insight into the structural and functional aspects of hexose transporters from other organisms. Similar remarks apply to the solution of the glycerol-3-phosphate transporter of Escherichia coli
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  • ••One of two papers that provide the firststructural insight for the major facilitator superfamily of transporters, for which crystal structures have been hitherto lacking. The lactose permease has been one of the most intensively studied transporters and will provide great insight into the structural and functional aspects of hexose transporters from other organisms. Similar remarks apply to the solution of the glycerol-3-phosphate transporter of Escherichia coli.

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