Bibliography
- BURRIS TP, MCCABE ERB: Nuclear Receptors and Genetic Disease. Academic Press, San Diego (2001).
- ••Book reviewing NRs and their role inhuman disease, with emphasis on mutations.
- STEINMETZ AC, RENAUD JP, MORAS D: Binding of ligands and activation of transcription by nuclear receptors. Anna. Rev Biophys. Biomol. Struct. (2001) 30:329–359.
- FREEDMAN LP: Increasing the complexity of coactivation in nuclear receptor signaling. Cell (1999) 97:5–8.
- ALBERT S, GAUDAN S, KNIGGE H et al.: Computer-assisted generation of a protein-interaction database for nuclear receptors. MM. Endocrinol (2003) 17:1555–1567.
- •A global view of protein interactions involving NRs.
- THOMPSON EB, KUMAR R: DNA binding of nuclear hormone receptors influences their structure and function. Biochem. Biophys. Res. Commun. (2003) 306:1–4.
- WONG CW, MCNALLY C, NICKBARG E, KOMM BS, CHESKIS BJ: Estrogen receptor-interacting protein that modulates its nongenomic activity-crosstalk with Src/Erk phosphorylation cascade. Proc. Natl. Acad. Sci.USA (2002) 99:14783–14788.
- SLADEK R, GIGUERE V: Orphan Nuclear Receptors: An Emerging Family of Metabolic Regulators. In: Hormones and Signalling. O'Malley BW (Ed.), Academic Press (2000):23–87.
- ••Excellent review on the so-called'orphan receptors'.
- KALLEN JA, SCHLAEPPI JM, BITSCH F et al.: X-ray structure of the hRORa LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORa. Structure (2002) 10:1697–1707.
- WISELY GB, MILLER AB, DAVIS RG et al.: Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids. Structure (2002) 10:1225–1234.
- DHE-PAGANON S, DUDA K, IWAMOTO M, CHI YI, SHOELSON SE: Crystal structure of the HNF4a ligand binding domain in complex with endogenous fatty acid ligand. Biol. Chem. (2002) 277:37973–37976.
- BILLAS IM, MOULINIER L, ROCHEL N, MORAS D: Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects. J. Biol. Chem. (2001) 276:7465–7474.
- GRESCHIK H, WURTZ JM et al: Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3. Ma Cell. (2002) 9:303–313.
- BAKER KD, SHEWCHUK LM, KOZLOVA T et al.: The Drosophila orphan nuclear receptor DHR38 mediates anatypical ecdysteroid signaling pathway. Cell (2003) 113:731–742.
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- WANSA KD, HARRIS JM, YANG, ORDENTLICH P, MUSCAT GE: The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine. J. Biol. Chem. (2003) 278:24776–24790.
- MITSIADES N, MITSIADES CS, RICHARDSON PG et al: Molecular sequelae of histone deacetylase inhibition in human malignant B cells. Blood (2003) 101:4055–4062.
- WATKINS RE, MAGLICH JM, MOORE LB et al: 2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin. Biochemistry (2003) 42:1430–1438.
- HONKAKOSKI P, SUEYOSHI T, NEGISHI M: Drug-activated nuclear receptors CAR and PXR. Ann. Med. (2003) 35:172–182.
- LEVINE M, TJIAN R: Transcription regulation and animal diversity. Nature (2003) 424:147–151.
- ••A global, yet concise, view of transcriptionregulation in animals.
Websites
- http://receptors.ucsEedu/NR NucleaRDB: an information system for nuclear receptors.
- •Emphasis on sequence alignments, structures and mutations.
- http://nrr.georgetown.edu/nrr/NRR.html The nuclear receptor resource.
- •General resource on NRs.
- www.ens-lyon.fr/LBMC/laudet/ nurebase.html Nuclear receptor database.
- •Nomenclature and evolution of the NR superfamily.