Advanced search
Publication Cover
Expert Opinion on Drug Safety Volume 2, 2003 - Issue 4
Submit an article Journal homepage
350
Views
18
CrossRef citations to date
0
Altmetric
Review

Haematological safety of antipsychotic drugs

RL Hall Department of Haematology, Southampton University Hospitals Trust, Southampton, Hampshire, SO16 6YD, UK. [email protected]
,
AG Smith Department of Haematology, Southampton University Hospitals Trust, Southampton, Hampshire, SO16 6YD, UK. [email protected]
&
J Guy Edwards Department of Haematology, Southampton University Hospitals Trust, Southampton, Hampshire, SO16 6YD, UK. [email protected]
Pages 395-399 | Published online: 03 Mar 2005

Bibliography

  • ARANA GW: An overview of side effects caused by typical antipsychotics. J. Clin. Psychiatry (2000) 61(S8):S5–S11.
  • EDWARDS JG: Unwanted effects of psychotropic drugs. I. Effects on human physiological systems. In: Seminars in Clinical Psychopharmacology. King DJ (Ed), Gaskell, London. In Press.
  • BALON MD, BERCHOU R: Hematologic side effects of psychotropic drugs. Psychosomatics (1986) 27(2):119–127.
  • •Good overview review article.
  • BALESTRIERI M, VAMPINI C, BELLANTUONO C: Efficacy and safety of novel antipsychotics: a critical review Hum. Psychopharmacol (2000) 15:499–512.
  • GEDDES J, FREEMANTLE N, HARRISON P, BEBBINGTON P: Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis. Br. Med J. (2000) 321:1371–1376.
  • KANE J, HONIGFELD G, SINGER J, MELTZER HY: Clozapine for the treatment-resistant schizophrenic: a double-blind comparison with chlorpromazine. Arch. Gen. Psychiatry (1988) 45:789–796.
  • MELTZER FLY, BASTANI B, KWON K et al.: A prospective study of clozapine in the treatment of resistant schizophrenic patients. Psychopharmacology (1989) 99:S68–S72.
  • MELTZER HY: Dimensions of outcome with clozapine. Br. J. Psychiatry (1992) 160\(Suppl. 17):46–53.
  • MELTZER FLY, ALPHS L, GREEN AI et al.: Clozapine treatment for suicidality in schizophrenia: International Suicide Prevention Trial (InterSePT). Arch. Gen. Psychiatry (2003) 60:82–91.
  • BARNES TRE, MCPHILLIPS MA: Critical analysis and comparison of the side-effect and safety profiles of the new antipsychotics. Br. J. Psychiatry (1999) 174(538):534–543.
  • LIEBERMAN JA, JOHNS CA, KANE JA et al.: Clozapine-induced agranulocytosis: non-cross-reactivity with other psychotropic drugs. J. Clin. Psychiatry (1988) 49(7):271–277.
  • •Particularly interesting as the case details are revealed.
  • ATKIN K, KENDALL F, GOULD D, FREEMAN H: Neutropenia and agranulocytosis in patients receiving clozapine in the UK and Ireland. Br. J. Psychiatry (1966) 169:483–488.
  • •Describes UK cases.
  • WAHLBECK K, CHEINE M, ESSALI MA, REZK E: Clozapine vs 'typical' neuroleptic medication for schizophrenia (Cochrane review). In: The Cochrane Library Issue 3. Update Software, Oxford (1998).
  • IDANPAAN-HEIKKILA J, ALHAVA E, OLKINUORA M, PALVA I: Clozapine and agranulocytosis. Lancet (1975) 2:611. Letter.
  • IDANPAAN-HEIKKILA J, ALHAVA E, OLKINUORA M, PALVA IP: Agranulocytosis during treatment with clozapine. Eur. J. Clin. Pharmacol. (1977) 11:193–198.
  • ANDERMAN B, GRIFFITH RW: Clozapine-induced agranulocytosis: a situation report up to August 1977. Eur. J. Clin. PharmacoL (1977) 11:199–201.
  • GRIFFITH RW, SAAMELI K: Clozapine and agranulocytosis. Lancet (1975) 2:657. Letter.
  • DE LA CHAPELLE A, KARI C, NURMINEN M, HERBERG S: Clozapine-induced agranulocytosis. A genetic and epidemiological study. Hum. Genet. (1977) 37:183–194.
  • EDWARDS JG: Withdrawal of psychotropic drugs from the market: I. From thalidomide to zimeldine. In: Human Psychopharmacology (Vol 6). Hindmarch I, Stonier PD (Eds), John Wiley, Chichester, UK (1997):199–214.
  • PISCIOTTA AV, KONINGS SA, CIESEMIER LL et al.: Cytotoxic activity in serum of patients with clozapine-induced agranulocytosis. J. Lab. Clin. Med. (1992) 119:254–266.
  • •Good insight into the mechanisms of the effects of the drug.
  • UETRECHT JP: Metabolism of clozapine by neutrophils. Drug Sal: (1992) 7(S1):S51–S56.
  • ALVIR JMJ, LIEBERMAN JA, SAFFERMAN AZ et al.: Clozapine-induced agranulocytosis: incidence and risk factors in the United States. N Engl J. Med (1993) 329(3):162–167.
  • PISCIOTTA AV: Drug-induced agranulocytosis peripheral destruction of polymorphonuclear leukocytes and their marrow precursors. Blood Rev. (1990) 4:226–237.
  • •Good overview review article.
  • VINCENT PC: Drug-induced aplastic anaemia and agranulocytosis: incidence and mechanisms. Drugs (1986) 31:52–63.
  • BARBUI C, CAMPOMORI A, BONATI M: Clozapine and blood dyscrasias different from agranulocytosis. Can. J. Psychiatry (1997) 42(9):981–982.
  • CHATTERTON R Eosinophilia after commencement of clozapine treatment. Aust. NZ J. Psychiatry (1997) 31:874–876.
  • WEIDE R, KOPPLER H, HEYMANNS J et al: Successful treatment of clozapine-induced agranulocytosis with granulocyte-colony stimulating factor (G-CSF). Br. J. Haematol (1992) 80:557–559.
  • MILLER DD: Review and management of clozapine side effects. J. Clin. Psychiatry (2000) 61(58):514–517.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.