Highly reproducible powder aerosolisation for lung delivery using powder-specific electromechanical vibration

Bibliography

• SUTHERLAND ER, CHERNIACK RM: Management of chronic obstructive pulmonary disease. N Engl. J. Med. (2004) 350(20:2689–2697.
   Google Scholar
• PRIME D, ATKINS PJ, SLATER A, SUMBY B: Review of dry powder inhalers. Adv. Drug Deliver. Rev. (1997) 26:51–58.
   Google Scholar
• CROWDER TM, LOUEY MD, SETHURAMAN VV, SMYTH HD, HICKEY AJ: 2001: an odyssey in inhaler formulations and design. Pharm. Tech. (2001) 25(7):99–113.
   Google Scholar
• CLARK AR, HOLLINGWORTH AM: The relationship between powder inhaler resistance and peak inspiratory conditions in healthy volunteers - implications for in vitro testing. J. Aerosol Med. (1993) 6(2):99–110.
   Google Scholar
• HINDLE M, BYRON PR: Dose emissions from marketed dry powder inhalers. Int. J. Pharm. (1995) 116:169–177.
   Google Scholar
• BOER AH, GJALTEMA D, HAGEDOORN P: Inhalation characteristics and their effects on in vitro drug delivery from dry powder inhalers. Part 2: effect of peak flow rate (PFIR) and inspiration time on the in vitro release from three different types of commercial dry powder inhalers. Int. J. Pharm. (1996) 138:45–56.
   Google Scholar
• CROWDER TM, ROSATI JA, SCHROETER JD, HICKEY AJ, MARTONEN TB: Fundamental effects of particle morphology on lung delivery: predictions of Stokes' law and the particular relevance to dry powder inhaler formulation and development. Pharm. Res. (2002) 19(3):239–245.
   Google Scholar
• ATKINS PJ, CROWDER TM: The design and development of inhalation drug delivery systems. In: Pharmaceutical Inhalation Aerosol Technology. AJ Hickey (Ed.), Marcel Dekker, New York, NY, USA (2004):279–309.
   Google Scholar
• PEART J, CLARKE MJ: New developments in dry powder inhaler technology. Am. Pharm. Rev. (2001) 4(3):37–45.
   Google Scholar
• HICKEY AJ, CONCESSIO NM, VAN OORT PLATZ RM: Factors influencing the dispersion of dry powders as aerosols. Pharm. Tech. (1994) 18(8):58–64.
   Google Scholar
• HICKEY AJ CONCESSIO NM: Chaos in rotating lactose powder beds. Part. Sci. TechnoL (1996) 14:15–25.
   Google Scholar
• HICKEY AJ, CONCESSIO NM: descriptors of irregular particle morphology and powder properties. Adv. Drug Deliver. Rev. (1997) 26:29–40.
   Google Scholar
• CONCESSIO NM, VAN OORT KNOWLES MR HICKEY AJ: Pharmaceutical dry powder aerosols: correlation of powder properties with dose delivery and implications for pharmacodynamic effect. Pharm. Res. (1999) 16(6):828–834.
   Google Scholar
• PHILLIPS CL, NAGLE HT: Digital Control System Analysis and Design. Prentice hall, Englewood Cliffs, NJ, USA (1995):685.
   Google Scholar
• CROWDER TM, FIELDS TB, HICKEY AJ: Signal processing and analysis applied to powder behavior in a rotating drum. Part. Part. Syst. Charact. (1999) 16(4):191–196.
   Google Scholar
• SOMMIER N, PORTON P, EVESQUE P et al.: Magnetic resonance imaging investigation of the mixing-segregation process in a pharmaceutical blender. Int. J. Pharm. (2001) 222:243–258.
   Google Scholar
• METCALFE G, SHINBROT T, MCCARTHY JJ, OTTINO JM: Avalanche mixing of granular solids. Nature (1995) 374:39–41.
   Google Scholar
• KHAKHAR DV, MCCARTHY JJ, GILCHRIST JF, OTTINO JM: Chaotic mixing of granular materials in two-dimensional tumbling mixers. Chaos (1999) 9(1):195–205.
   Google Scholar
• EVESQUE P: Analysis of the statistics ofsandpile avalanches using soil-mechanics results and concepts. Phys. Rev. A (1991) 43(6):2720–2740.
   Google Scholar
• JAEGER HM, LIU CH, NAGEL SR: Relaxation at the angle of repose. Phys. Rev. Lett. (1989) 62(1):40–43.
   Google Scholar
• BAK P, TANG C, WISENFELD K: Self-organized criticality: an explanation of 1/f noise. Phys. Rev. Lett. (1987) 59:381–384.
   Google Scholar
• BAUMANN G, WOLF DE: Self-organized criticality in a two-dimensional rotating drum model. Phys. Rev. E (1996) 54(5):R4504–R4507.
   Google Scholar
• MORALES-GAMBOA E, LOMNITZ-ADLER J, ROMERO-ROCHIN V, CHICHARRO-SERRA R, PERALTA-FABI R: Two-dimensional avalanches as stochastic markov processes. Phys. Rev. E (1993) 47(4):R2229–R2232.
   Google Scholar
• KAYE BH, GRATTON-LIIMATAINEN J, FADDIS N: Studying the avalanching behaviour of a powder in a rotating disc. Part. Part. Syst. Charact. (1995) 12:232–236.
   Google Scholar
• BAUMANN G, JÁNOSI IM, WOLF DE: Surface properties and flow of granular material in a two-dimensional rotating-drum model. Phys. Rev. E (1995) 51(3):1879–1888.
   Google Scholar
• TROWBRIDGE L, WILLIAMS AC, YORK P, DENNIS AB, WORTHINGTON VL: A Comparison of methods for determining powder flow: correlation with tableting performance. Pharm. Res. (1997) 14:S–415.
   Google Scholar
• FEELEY JC, YORK P, SUMBY BS, DICKS H: Determination of surface properties and flow characteristics of salbutamol sulfate, before and after micronization. Int. J. Pharm. (1998) 172:89–96.
   Google Scholar
• DOROGOVTSEV SN: Avalanche mixing of granular materials: time taken for the disappearance of the pure fraction. Tech. Phys. (1997) 42:1346–1348.
   Google Scholar
• DURY CM, RISTOW GH, NAKAGAWA M: Angle of repose in a rotating drum. In: Powders and Grains 97. AA Balkema, Durham, NC, USA (1997):507–510.
   Google Scholar
• KAWAI H: The piezoelectricity of poly(vinylidene fluoride). Japan J. Appl. Phys. (1969) 8:975–976.
   Google Scholar
• FRADEN J: Application of piezo/ pyroelectric films in medical transducers. J. Clinical Eng. (1988) 13(2):133–138.
   Google Scholar
• BROWN LF: Design considerations for piezoelectric polymer ultrasound transducers. IEEE Trans. Ultrasonics, Ferroelectrics and Freq. Control (2000) 47(6):1377–1396.
   Google Scholar